초록 ▼

An electrode assembly and a method of forming an anhydrous reservoir layer of an electrode assembly in an electrotransport transdermal agent delivery device are provided. The reservoir layer is adapted to be placed in agent-transmitting relation with a body surface and an electrode in electrical con

An electrode assembly and a method of forming an anhydrous reservoir layer of an electrode assembly in an electrotransport transdermal agent delivery device are provided. The reservoir layer is adapted to be placed in agent-transmitting relation with a body surface and an electrode in electrical contact with a power source and the reservoir layer. The method includes the steps of dissolving a beneficial agent in a solvent, applying the solvent and dissolved beneficial agent to a surface of a hydrophilic polymer filtration membrane, removing the solvent from the surface of the filtration membrane, and disposing the beneficial agent/filtration membrane within the electrode assembly.

대표청구항 ▼

1. A multilaminate dry state electrode assembly for an electrically powered electrotransport agent delivery device, the electrode assembly having a reservoir layer and an electrode layer the reservoir layer being adapted to be placed in agent-transmitting relation with a body surface, the reservoir

1. A multilaminate dry state electrode assembly for an electrically powered electrotransport agent delivery device, the electrode assembly having a reservoir layer and an electrode layer the reservoir layer being adapted to be placed in agent-transmitting relation with a body surface, the reservoir layer comprising a substantially non-hydrated hydratable matrix for containing an agent to be delivered, said matrix having a body surface distal side and a body surface proximal side, said reservoir further comprising a hydrating material layer, said hydrating material layer located either between the electrode layer and the matrix or on the body surface proximal side of the matrix, and the electrode layer being in electrical contact with the reservoir layer and adapted to be placed in electrical contact with a power source, the reservour layer formed by the process of:dissolving the agent in a solvent; applying the solvent and dissolved agent to a surface of a hydrophilic polymer fitration membrane; removing the solvent from the surface of the hydrophilic polymer filtration membrane; disposing the agent/polymer filtration membrane within the electrode assembly.