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[미국특허] Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-025/34
  • A61F-013/00
  • A61F-009/02
  • A61L-015/16
출원번호 US-0594294 (2000-06-15)
발명자 / 주소
  • Michael A. Repka
  • Staci L. Repka
  • James W. McGinity
대리인 / 주소
    Rick Matos
인용정보 피인용 횟수 : 126  인용 특허 : 11

초록 ▼

The present invention includes a hot-melt extruded film and method of preparation thereof. The film is made from a precursor composition containing at least a water soluble or water swellable thermoplastic polymer, preferably HPC and/or PEO, and a bioadhesive polymer. The film can also contain a the

대표청구항 ▼

1. A hot-melt extruded composition comprising:about 30-95% wt. of one or more water-soluble or water-swellable thermoplastic polymers; about 1-25% wt. of polycarbophil; about 1-60% wt. of poly(ethylene oxide); about 0.1-10% wt. of an organic acid; about 0.01-10% wt. of an antioxidant; and about 0-50

이 특허에 인용된 특허 (11) 인용/피인용 타임라인 분석

  1. Scholz Matthew T. ; Scherrer Robert A. ; Marecki Nelda M. ; Chen Yen-Lane ; Barkhaus Joan K., Bioadhesive composition and patch.
    상세보기
  2. Schiraldi Michael T. (East Brunswick NJ) Perl Martin M. (Brooklyn NY) Rubin Howard (Rockaway NJ), Bioadhesive extruded film for intra-oral drug delivery and process.
    상세보기
  3. Gurtler Florian,CHX ; Gurny Robert,CHX, Bioadhesive ophthalmic insert.
    상세보기
  4. Repka Michael A. ; Gerding Thomas G., Bioadhesive polyethylene glycol ointment for medicaments.
    상세보기
  5. Mooney Mark T. ; Schiraldi Michael T., Extrudable compositions for topical or transdermal drug delivery.
    상세보기
  6. Tapolsky Gilles H. ; Osborne David W., Pharmaceutical preparation applicable to mucosal surfaces and body tissues.
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  7. Suzuki Yoshiki (Hino JPX) Ikura Hiroshi (Hino JPX) Noguchi Toshihide (Tokyo JPX) Izumizawa Katsunori (Yokohama JPX) Kinoshita ; deceased Shiro (late of Tokyo JPX by Kimiko Kinoshita ; Atsuhiro Kinosh, Pharmaceutical preparation for remedy of periodontal disease and process for production thereof.
    상세보기
  8. Repka Michael A. (Pleasanton TX) Gerding Thomas G. (Georgetown TX), Polyethylene glycol ointment for apthous ulcers.
    상세보기
  9. Trenzeluk Theodore (Manville NJ), Skin therapeutic mixture containing eupatorium extract.
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  10. Pinkus A. George, Tablets or biologically acceptable implants for long-term antiinflammatory drug release.
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  11. Biegajski James E. (Foster City CA) Venkatraman Subbu S. (Palo Alto CA) Scott Ann M. (Mountain View CA), Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavi.
    상세보기

이 특허를 인용한 특허 (126) 인용/피인용 타임라인 분석

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