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Compositions and methods for the treatment of anorectal disorders 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/55
  • A61K-031/50
  • A61K-031/40
  • A61K-031/13
출원번호 US-0595390 (2000-06-14)
발명자 / 주소
  • Thomas P. Parks
  • Vivien Mak
  • Jung-Chung Lee
  • Charles Lee
출원인 / 주소
  • Cellergy Pharmaceuticals, Inc.
대리인 / 주소
    Townsend and Townsend and Crew LLP
인용정보 피인용 횟수 : 120  인용 특허 : 6

초록 ▼

Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2-) scavengers, .beta.-adrenergic agonists, cAMP-dependent protein kinase activators, .alpha.1-adrenergic antagonists, L-type Ca2+ channel blockers,

대표청구항

1. A method of treating an anorectal disorder, and for controlling the pain associated therewith, the method comprising administering to a subject in need of such treatment a therapeutically effective amount of a topical composition comprising a cGMP modulating phosphodiesterase inhibitor.

이 특허에 인용된 특허 (6)

  1. Pasricha Pankai J. (5007 Southern Star Ter. Columbia MD 21044) Kalloo Anthony N. (10708 Forestgate Pl. Glenndale MD 20769), Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction.
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  2. Fogel Barry S., Method for treating painful conditions of the anal region and compositions therefor.
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  3. Gorfine Stephen R. (New York NY), Nitric oxide donor composition and method for treatment of anal disorders.
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  4. Garvey David S. ; Schroeder Joseph D. ; Saenz de Tejada Inigo,ESX, Nitrosated and nitrosylated .alpha.-adrenergic receptor antagonist compounds, compositions and their uses.
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  5. Garvey David S. ; Saenz de Tejada Inigo,ESX, Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses.
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  6. Singh Amarjit,INX ; Jain Rajesh,INX ; Singla Anil Kumar,INX, Pharmaceutical composition for the control and treatment of anorectal and colonic diseases.
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