초록 ▼

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be app

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.

대표청구항 ▼

1. A method of applying an adhesive to a work surface on a subject, the method comprising applying to said work surface a suction force from a remote vacuum source connected with a suction channel, to prepare the work surface for the application of adhesive, the suction channel being a component of

1. A method of applying an adhesive to a work surface on a subject, the method comprising applying to said work surface a suction force from a remote vacuum source connected with a suction channel, to prepare the work surface for the application of adhesive, the suction channel being a component of an applicator device, followed by depositing said adhesive from said applicator device via a dispensing channel, the dispensing channel also being a component of said applicator device, onto said work surface, wherein the suction channel is disposed adjacent the dispensing channel and interferes neither visually nor functionally with the dispensing of adhesive from the dispensing channel, and wherein the amount of adhesive dispensed is measured audibly.