초록 ▼

An optical detection and orientation device is provided comprising housing having an excitation light source, an optical element for reflecting the excitation light to an aspherical lens and transmitting light emitted by a fluorophore excited by said excitation light, a focussing lens for focusing t

An optical detection and orientation device is provided comprising housing having an excitation light source, an optical element for reflecting the excitation light to an aspherical lens and transmitting light emitted by a fluorophore excited by said excitation light, a focussing lens for focusing the emitted light onto the entry of an optical fiber, which serves as a confocal aperture, and means for accurately moving said housing over a small area in relation to a channel in a microfluidic device. The optical detection and orientation device finds use in identifying the center of the channel and detecting fluorophores in the channel during operations involving fluorescent signals.

대표청구항 ▼

1. An optical detection and orientation system for irradiating a fluorescent sample in a microchannel and detecting light emanating from a solid substrate and fluorescence emitted from said channel, wherein said microchannel is in a solid substrate, said system comprising:a movable optical train com

1. An optical detection and orientation system for irradiating a fluorescent sample in a microchannel and detecting light emanating from a solid substrate and fluorescence emitted from said channel, wherein said microchannel is in a solid substrate, said system comprising:a movable optical train comprising a source of excitation light and means for directing said light onto said solid substrate; means for receiving said light emanating from said solid substrate and transferring said emanating light for analysis; and means for moving said optical train and excitation light across the surface of said solid substrate comprising said microchannel and centering said optical train over said microchannel in response to the changes in light emanating from said solid substrate.