초록

Hollow particles having a shell substantially composed of calcium-phosphate, methods for preparing the same, and methods of use are disclosed. The particles are obtained by differential immersion of silica-based, calcium and phosphate containing glass particles.

대표청구항 ▼

1. A hollow particle having an intact nanoporous calcium phosphate shell, said nanoporous calcium phosphate shell further comprising up to about 9.3% silicon, and having an outer diameter of up to about 5 mm, said hollow particle prepared by the process comprising the step of immersing bioactive gla

1. A hollow particle having an intact nanoporous calcium phosphate shell, said nanoporous calcium phosphate shell further comprising up to about 9.3% silicon, and having an outer diameter of up to about 5 mm, said hollow particle prepared by the process comprising the step of immersing bioactive glass particles comprising from about 40% to about 100% SiO, in an aqueous solution undersaturated in soluble silica for a period sufficient to allow from about 80% to about 100% of the silicon to dissolve from said bioactive glass particles.