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Methods for fine powder formation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
출원번호 US-0543309 (2000-04-05)
발명자 / 주소
  • Robert Feldstein
  • Solomon S. Steiner
출원인 / 주소
  • Pharmaceutical Discovery Corporation
대리인 / 주소
    Holland & Knight LLP
인용정보 피인용 횟수 : 69  인용 특허 : 9

초록

Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizin

대표청구항

1. A method of making fine particles of a therapeutic or diagnostic material consisting of(a) dissolving a therapeutic or diagnostic material in a solvent to form a dilute solution; (b) forming particles which are gelled or chelated; and (c) removing the solvent from the therapeutic or diagnostic ma

이 특허에 인용된 특허 (9)

  1. Platz Robert M. ; Brewer Thomas K. ; Boardman Terence D., Dispersible macromolecule compositions and methods for their preparation and use.
  2. Oyler ; Jr. James R. (2801 Ocean Dr. Vero Beach FL 32963), Liquid substances freeze-drying systems and methods.
  3. Patton John S. ; Platz Robert M., Method and device for delivering aerosolized medicaments.
  4. Burke Paul A., Method for fabricating polymer-based controlled-release devices.
  5. Ozawa Yasuo (Ageo JPX) Koyama Ikuo (Hasuda JPX) Shimano Kimihide (Ageo JPX), Method of producing fine coated pharmaceutical preparation.
  6. Patton John S. ; Foster Linda ; Platz Robert M., Methods and compositions for pulmonary delivery of insulin.
  7. Rhim Won-Kyu (Pasadena CA) Hyson Michael T. (Glendale CA) Chung Sang-Kun (Diamond Bar CA) Colvin Michael S. (Malibu CA) Chang Manchium (Los Angeles CA), Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops.
  8. Bystrom Katarina,SEX ; Nilsson Per-Gunnar,SEX, Powders for inhalation.
  9. Gombotz Wayne R. (Lexington MA) Healy Michael S. (E. Bridgewater MA) Brown Larry R. (Newton MA), Very low temperature casting of controlled release microspheres.

이 특허를 인용한 특허 (69)

  1. Alfille, Jean-Pascal, Apparatus and method for laser cutting with a laser implementing gas pulses, the frequency or pressure of which is controlled.
  2. Adamo, Benoit; Polidoro, John M.; Overfield, Dennis; Sahi, Carl R.; Laurenzi, Brendan; Smutney, Chad C.; Kinsey, P. Spencer, Apparatus and method for simulating inhalation efforts.
  3. Adamo, Benoit; McLean, Scott; Smutney, Chad C.; Polidoro, John M.; Sahi, Carl R., Apparatus, system and method for measuring resistance of an inhaler.
  4. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
  5. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
  6. Lander, Cynthia; Brophy, Colleen, Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition.
  7. Lander, Cynthia; Brophy, Colleen, Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition.
  8. Richardson, Peter; Baughman, Robert A.; Leone-Bay, Andrea; Costello, Donald, Delivery of active agents.
  9. Antunovich, Jason J.; Hamfeldt, Arthur T.; Woods, Rodney J.; Shum, Sam C., Determining percent solids in suspension using Raman spectroscopy.
  10. Antunovich, Jason J.; Hamfeldt, Arthur T.; Woods, Rodney J.; Shum, Sam C., Determining percent solids in suspension using Raman spectroscopy.
  11. Antunovich, Jason J.; Hamfeldt, Arthur T.; Woods, Rodney J.; Shum, Sam C., Determining percent solids in suspension using raman spectroscopy.
  12. Grant, Marshall L.; Stowell, Grayson W.; Menkin, Paul, Diketopiperazine microparticles with defined specific surface areas.
  13. Grant, Marshall L.; Stowell, Grayson W.; Menkin, Paul, Diketopiperazine microparticles with defined specific surface areas.
  14. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
  15. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
  16. Smutney, Chad C.; Adamo, Benoit; Laurenzi, Brendan F.; Kinsey, P. Spencer, Dry powder drug delivery system and methods.
  17. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl; Billings, Christine; Marino, Mark T., Dry powder drug delivery system and methods.
  18. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  19. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony; He, Tom; Mann, Alfred, Dry powder inhaler and system for drug delivery.
  20. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
  21. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
  22. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfiled, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
  23. Fabio, Karine; Guarneri, Joseph J.; Curley, Kieran; Grant, Marshall L.; Leone-Bay, Andrea, Heat-stable dry powder pharmaceutical compositions and methods.
  24. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
  25. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
  26. Hokenson, Mark; Oberg, Keith A., Increasing drug affinity for crystalline microparticle surfaces.
  27. Smutney, Chad C.; Leone-Bay, Andrea; Galarza, Jose M.; Munoz, Hector; Martin, George R.; Grant, Marshall L., Inhalable vaccine compositions and methods.
  28. Poole, Trent; Steiner, Solomon S., Inhalation apparatus.
  29. Steiner, Solomon S.; Pohl, Roderike; Li, Ming; Hauser, Robert, Insulin formulations for rapid uptake.
  30. Overfield, Dennis; Sahi, Carl R.; Adamo, Benoit; Kinsey, P. Spencer; McLean, Scott; Polidoro, John M.; Smutney, Chad C., Interactive apparatus and method for real-time profiling of inhalation efforts.
  31. Leone-Bay, Andrea; Stowell, Grayson W.; Guarneri, Joseph J.; Carlson, Dawn M.; Grant, Marshall; Smutney, Chad C., Method and composition for treating migraines.
  32. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Method for delivery of monomeric or dimeric insulin complexed to diketopiperazine microparticles.
  33. Steiner, Solomon S.; Feldstein, Robert; Lian, Huiling; Rhodes, Christopher A.; Shen, Gregory S., Method for drug delivery to the pulmonary system.
  34. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  35. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  36. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  37. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
  38. Boss, Anders Hasager; Petrucci, Richard; Howard, Campbell; Mann, Alfred, Method of controlling glycemia by ultrarapid acting insulin without adjusting an insulin dose for meal content.
  39. Hokenson, Mark; Oberg, Keith A., Method of drug formulation.
  40. Hokenson, Mark; Oberg, Keith A., Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces.
  41. Hokenson, Mark; Oberg, Keith A., Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces.
  42. Hokenson, Mark; Oberg, Keith A., Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces.
  43. Oberg, Keith A., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  44. Oberg, Keith A.; Sulner, Joseph, Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  45. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  46. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
  47. Hokenson, Mark; Oberg, Keith A., Method of drug formulation of compositions comprising crystalline microparticle surfaces.
  48. Richardson, Peter; Baughman, Robert A.; Costello, Donald, Method of preventing adverse effects by GLP-1.
  49. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Method of treating diabetes type 2 by administering ultrarapid acting insulin.
  50. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Method of treating diabetes type 2 by metformin and an ultrarapid acting insulin.
  51. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Methods and compositions for delivering peptides.
  52. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Methods and compositions for delivering peptides.
  53. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  54. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  55. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
  56. Feldstein, Robert; Steiner, Solomon S., Methods for fine powder formation.
  57. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
  58. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
  59. Wang, Zhaolin; Finlay, Warren H., Powder formation by atmospheric spray-freeze drying.
  60. Steiner, Solomon S.; Pohl, Roderike, Rapid acting and long acting insulin combination formulations.
  61. Steiner, Solomon S.; Pohl, Roderike, Rapid acting and long acting insulin combination formulations.
  62. Pohl, Roderike; Steiner, Solomon S., Rapid acting injectable insulin compositions.
  63. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  64. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  65. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  66. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
  67. Lander, Cynthia; Brophy, Colleen; Peterson, Caryn; Luber, Andrew, Use of MKS inhibitor peptide-containing compositions for treating non-small cell lung cancer with same.
  68. Boss, Anders Hasager; Petrucci, Richard; Howard, Campbell; Mann, Alfred, Use of ultrarapid acting insulin.
  69. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Use of ultrarapid acting insulin.
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