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특허 상세정보

Devices and methods for applying a mixture of two or more liquid components to form a biomaterial

국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61B-017/08   
미국특허분류(USC) 606/214; 606/213
출원번호 US-0970291 (1997-11-14)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    John M. Kilcoyne
인용정보 피인용 횟수 : 17  인용 특허 : 17
초록

Novel methods and devices which provide enhanced mixing and application of two liquid components to form a biomaterial with minimized aerosols is achieved using air flow rates below about 1.25 liters/minute in combination with a ratio of air flow to total liquid flow of from about 150:1 up to about 1500:1. Preferably the air flow is below about 1 liter/minute and the ratio of air flow to total liquid flow is from about 200:1 to about 1200:1. The parameters are ideally suited for the spray application of components which form a surgical sealant, e.g., a f...

대표
청구항

1. An applicator system for applying two or more liquids to a desired site including a fibrin monomer liquid and a liquid solution for polymerizing the fibrin monomer, which liquids form a biomaterial upon mixing comprising;a) a source of said liquids comprising a discrete container for each of said liquids; b) fluid transferring means for transferring fluid, said fluid transferring means having a first end and a second end, said first end being connected to said containers wherein said fluid tranferring means includes discrete channels or lumen for each...

이 특허에 인용된 특허 (17)

  1. Redl Heinz (Vienna ATX) Habison Georg (Vienna ATX). Apparatus for applying a tissue adhesive. USP1986124631055.
  2. Redl Heinz (Vienna ATX) Kriwetz Gert (Graz ATX). Apparatus for applying a tissue adhesive on the basis of human or animal proteins. USP1982114359049.
  3. Reidel Guillermo (Marburg DEX) Weitzel Dietmar (Marburg DEX) Grothoff Hans (Dortmund DEX). Apparatus for spraying a mixture of two components. USP1997025605255.
  4. Fukunaga Nobuto (Tamana JPX) Kawakami Katsumi (Kumamoto JPX) Uchida Takanori (Kumamoto JPX) Ishihara Yoshimitsu (Kikuchi-gun JPX). Applicator for applying a biocompatible adhesive. USP1996125582596.
  5. Eibl Johann (Vienna ATX) Seelich Thomas (Vienna ATX) Redl Heinz (Vienna ATX) Habison Georg (Vienna ATX). Arrangement for applying a tissue adhesive. USP1988044735616.
  6. Capozzi Emil E. (Costa Mesa CA) Cooksten H. Stephen (Malibu CA). Biological syringe system. USP1992055116315.
  7. Capozzi Emil E. (Costa Mesa CA) Cookston H. Stephen (Pacific Palisades CA). Biological syringe system. USP1990124978336.
  8. Miller Curtis H. (Burnsville MN) Arenberg I. Kaufman (Englewood CO) Altshuler John H. (Englewood CO). Fibrin glue delivery system. USP1989104874368.
  9. Holm Niels-Erik (Birkerod DKX). Fibrin sealant applicatoor. USP1997025605541.
  10. Marx Gerard. Fibrin sealant glue-gun. USP1998065759169.
  11. Avoy Donald R. (Los Gatos CA). Fibrinogen dispensing kit. USP1990024902281.
  12. Epstein Gordon H. (135 Kootenai Dr. Fremont CA 94539). Method and apparatus for preparing fibrinogen adhesive from whole blood. USP1993075226877.
  13. Burgener John A. (944 Meadow Wood Rd. Mississauga ; Ontario L5J 2S6 CAX). Parallel path induction pneumatic nebulizer. USP1995055411208.
  14. Zimmermann Josef (Sulzbach DEX). Spray head for the administration of a multi-component material by means of gas. USP1990054925108.
  15. Lonneman Alan (Plymouth MN) Miller Curtis H. (Burnsville MN). Sprayer assembly for physiologic glue. USP1994115368563.
  16. Coelho Philip H. ; Wolf Terry L. ; Menke Peter ; Alcone Jerry M.. Sprayer for fibrin glue. USP1998065759171.
  17. Salerno Tomas A. (Toronto UT CAX) Fox Douglas G. (Holladay UT). Surgical site visualization wand. USP1994085336170.

이 특허를 인용한 특허 피인용횟수: 17

  1. Gertner, Michael E.. Aerosol device to deliver bioactive agent. USP2009067544177.
  2. Ducharme, Richard W.; Sugg, David E.. Apparatus and methods for containing and delivering therapeutic agents. USP2013018361054.
  3. Ducharme, Richard W.. Apparatus and methods for delivering therapeutic agents. USP2017129839772.
  4. Redl, Heinz; Khakpour, Zafar; Ariagno, Scott R.; Kellner, Andreas; Zakarija, Lillian G.. Hand triggered tissue sealant spray apparatus and system. USP2009057537174.
  5. Fech, Andreas; Fischer, Klaus; Enderle, Markus; Szyrach, Mara. Nozzle for the supply of biological material, in particular cells, medical device with such a nozzle, use of a nozzle, method for mixing fluids and apparatus. USP2018019878126.
  6. von Lehe, Cathleen; Sirivong, Sengkham. Rapid exchange catheters and embolic protection devices. USP2016109456889.
  7. Brunk, Donald H.; Dimaio, Jr., William Gerald. Self-contained hand-held yoke-connected device for dispensing a two-part adhesive aerosol. USP2014038678238.
  8. Leopold, Phillip M.; Roberts, Allan. Spray devices and methods. USP2012108287566.
  9. Campbell, Patrick Kenneth; Driscoll, Arthur J.; Guest, Tom. Spray for fluent materials. USP2009117611494.
  10. Campbell, Patrick Kenneth; Driscoll, Arthur J.; Guest, Tom. Spray for fluent materials. USP2014118888749.
  11. Campbell, Patrick Kenneth; Driscoll, Arthur J; Guest, Thomas. Spray for fluent materials. USP2012048152777.
  12. Ducharme, Richard W. Systems and methods for delivering therapeutic agents. USP2015089101744.
  13. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene E.; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2016069375533.
  14. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2014058728032.
  15. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2012028118777.
  16. Gittard, Shaun D.. Therapeutic agents for delivery using a catheter and pressure source. USP2018019867931.
  17. Redl, Heinz; Khakpour, Zafar; Ariagno, Scott R.; Kellner, Andreas; Zakarija, Lillian G.. Tissue sealant applicator system. USP2013068469289.