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Emulsion vehicle for poorly soluble drugs 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-025/00
출원번호 US-0003173 (1998-01-05)
발명자 / 주소
  • Karel J. Lambert
  • Panayiotis P. Constantinides
  • Steven C. Quay
출원인 / 주소
  • Sonus Pharmaceuticals, Inc.
대리인 / 주소
    Christensen O'Connor Johnson Kindness PLLC
인용정보 피인용 횟수 : 110  인용 특허 : 30

초록 ▼

An emulsion of .alpha.-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylat

대표청구항 ▼

1. A pharmaceutical composition, comprising a chemotherapeutic agent, wherein the chemotherapeutic agent is at least one of a taxoid, a taxane, or a taxine; a tocopherol; tocopherol polyethylene glycol succinate; polyethylene glycol; a surfactant; and an aqueous phase; wherein the composition is an

이 특허에 인용된 특허 (30)

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  4. Janoff Andrew S. (Yardley PA) Bolcsak Lois E. (Lawrenceville NJ) Weiner Alan L. (Lawrenceville NJ) Tremblay Paul A. (Hamilton NJ) Bergamini Michael V. W. (Cupertino CA) Suddith Robert L. (Robbinsvill, Entrapment of water-insoluble compound in alpha tocopherol-based vesicles.
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  16. Kovacs Istvan (Debrecen HUX) Jusztin Marta (Debrecen HUX) Takacs Erzsebet (Debrecen HUX) Balazs Zoltan (Debrecen HUX) Kiss Ildiko (Ebes HUX) Varga Zsolt (Debrecen HUX) Jancso Sandor (Debrecen HUX) He, Oral pharmaceutical preparation.
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  25. Hendler Sheldon S. (La Jolla CA) Sanchez Robert (Carlsbad CA), Tocopherol-based antiviral agents and method of using same.
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  26. Peat, Raymond F., Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols.
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  27. Meybeck Alain (Courbevoie FRX) Bonte Frederic (Courbevoie FRX) Marechal Christian (Paris FRX), Use of a 상세보기
  • Stillman, Theodore, Vitamin E compositions and methods.
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