[미국특허]
Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C12Q-001/70
G01N-033/543
G01N-033/569
출원번호
US-0963842
(1997-11-04)
발명자
/ 주소
Stewart, Sandy J.
출원인 / 주소
Syngenta Investment Corporation
대리인 / 주소
Bruce Vrana
인용정보
피인용 횟수 :
26인용 특허 :
20
초록▼
The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously with the formation of the primary antigen-tes
The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously with the formation of the primary antigen-test substance complex. The primary antigen-test substance complex is then captured in a solid phase format having a plurality of interstitial spaces which facilitate rapid and efficient detection. The immunoassay of the present invention works over a wide range of environmental conditions and is simple enough to be used in the absence of laboratory facilities.
대표청구항▼
The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously with the formation of the primary antigen-tes
The present invention is drawn to an immunoassay capable of the rapid detection of a variety of test substances that may be present in a test sample. One feature of the invention is that extraction or isolation of the test substance occurs simultaneously with the formation of the primary antigen-test substance complex. The primary antigen-test substance complex is then captured in a solid phase format having a plurality of interstitial spaces which facilitate rapid and efficient detection. The immunoassay of the present invention works over a wide range of environmental conditions and is simple enough to be used in the absence of laboratory facilities. . Ferguson, R., et al., "Pattern-Dependent Correction of Mask Topography Effects for Alternating Phase-Shifting Masks", IBM Microelectronics, University of California Berkeley (12 pages). Toublan, O., et al., "Phase and Transmission Errors Aware OPC Solution for PSM: Feasibility Demonstration", Mentor Graphics Corp. (7 pages). Yanagishita, Y., et al., "Phase-Shifting Photolithography Applicable to Real IC Patterns", Fujitsu Limited (11 pages). Levenson, M., et al., "The Phase-Shifting Mask II: Imaging Simulations and Submicrometer Resist Exposures", IEEE Transactions on Electron Devices, vol. ED-31, No. 6, pp. 753-763, Jun. 1984. IBM, "Method to Produce Sizes in Openings in Photo Images Smaller Than Lithographic Minimum Size", IBM Technical Disclosure Bulletin, vol. 29, No. 3, p. 1328, Aug. 1986. Buraschi, M., et al., "Optical-Diffraction-Based Modulation of Photoresist Profile or Microlithography Applications", Optical Engineering, vol. 28, No. 6, pp. 654-658, Jun. 1989. Nitayama, A., et al., "New Phase Shifting Mask
Yamazaki Hiroshi (Nepean CAX) Blais Burton W. (Ottawa CAX), Antibodies or antigens bound to a macroporous hydrophobic synthetic polymer cloth for immunological techniques.
Yamazaki Hiroshi (Nepean CAX) Blais Burton W. (Ottawa CAX), Enzyme immunoassay with a macroporous hydrophobic synthetic polymer cloth containing an immobilized antibody or antigen.
Lankow Richard K. (Cinnaminson NJ) Miller Sally A. (Pennsauken NJ) Grothaus G. David (Delran NJ) Petersen Frank P. (Beverly NJ) Stocker Dennis R. (Yardley PA) Papa Stephanie L. (Merchantville NJ) Don, Method and a kit for diagnosing plant diseases.
Klose Sigmar (Berg DEX) Pasch Manfred (Tutzing DEX) Schlumberger Helmut (Polling DEX) Kleemann Wolfgang (Tutzing DEX) Vieth Friedhelm (Haunshofen DEX), Process and device for carrying out analytical determinations.
Stewart Sandy J. (Durham NC), Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic r.
Todd William J. (Baton Rouge LA) Barstad Paul A. (Frederick MD), Single incubation immuno sorbent assay method using particle labels to detect test antigen specific antibodies in presen.
Whitney, Scott E.; Wilkinson, Steven; Muller, Rolf, Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures.
Whitney, Scott E.; Ghirmai, Senait; Muller, Rolf, Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures.
Whitney, Scott E.; Wilkinson, Steven; Muller, Rolf, Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures.
Whitney, Scott E.; De Los Rios, Stephanie; Ghirmai, Senait; Muller, Rolf; Liberal, Vasco; Wilkinson, Steven P., Formulations and methods for stabilizing PCR reagents.
Battrell,C. Frederick; Shen,Mingchao; Weigl,Bernhard H.; Houkal,Jeffrey M.; Lancaster,Christy A.; Breidford,Wayne, Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing.
Barnhizer, Bret T.; Gazenko, Sergey, Methods and devices for rapid detection and identification of live microorganisms by aptamers and/or antibodies immobilized on permeable membranes.
Johnson, Brandon T.; Zappia, Thomas M.; Vogler, David A., Methods of preparing and operating portable, point-of-care, user-initiated fluidic assay systems.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.