초록 ▼

The present invention relates to a combination for surface treatment of a substrate, e.g. a nonwoven web, used in personal care product applications. The surface treatment combination not only provides adequate fluid handling properties, but also provides a topical delivery system effective in depos

The present invention relates to a combination for surface treatment of a substrate, e.g. a nonwoven web, used in personal care product applications. The surface treatment combination not only provides adequate fluid handling properties, but also provides a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a botanical extract on skin by an aqueous emulsion mediated dissolution of the agent from a substrate with subsequent transfer and deposition onto the skin. Coatings of the botanical extract on the skin resist removal, thereby preventing damage to the natural skin barrier and providing a protective barrier against chemically- and biochemically-induced skin damage.

대표청구항 ▼

The present invention relates to a combination for surface treatment of a substrate, e.g. a nonwoven web, used in personal care product applications. The surface treatment combination not only provides adequate fluid handling properties, but also provides a topical delivery system effective in depos

The present invention relates to a combination for surface treatment of a substrate, e.g. a nonwoven web, used in personal care product applications. The surface treatment combination not only provides adequate fluid handling properties, but also provides a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a botanical extract on skin by an aqueous emulsion mediated dissolution of the agent from a substrate with subsequent transfer and deposition onto the skin. Coatings of the botanical extract on the skin resist removal, thereby preventing damage to the natural skin barrier and providing a protective barrier against chemically- and biochemically-induced skin damage. e Protein GMP-140", J. Biol. Chem. 264:7768-7771 (1989). Hemmerich et al., "Structure of the O-Glycans in BlyCAM-1, and Endothelial-derived Ligand for L-selectin", The Journal of Biological Chemistry 270(20):12035-12047 (1995). Hoff et al., "Increased Expression of Sialyl-Dimeric LexAntigen in Liver Metastases of Human Colorectal Carcinoma", Cancer Research, 49:6883-6888 (1989). Hollengaugh et al., "Interaction of P-Selectin (CD62) and Its Cellular Ligand: Analysis of Critical Residues" Biochemistry, 32:2960-2966 (1993). Huang et al., "A Lymphocyte Homing Receptor (L-Selectin) Mediates the In Vitro Attachment of Lymphocytes to Myelinated Tracts of the Central Nervous System", J. Clin. Invest., 88:1778-1783 (1991). Jewell et al., "Cytokine Induction of Leucocyte Adhesion Molecules-1 (LAM-1) Expression on Chronic Lymphocytic Leukaemia Cells", Leukemia 6(5):400-404 1992). Johnston et al., "Cloning of GMP-140: Chromosomal Localization, Molecular Heterogeneity and Identification of cDNAs Predicting Both Membrane Bound and Soluble Proteins", Blood Suppl., 72:327a (1988). Johnston et al., "Cloning of GMP-140, a Granule Membrane Protein of Platelets and Endothelium: Sequence Similarity to Proteins Involved in Cell Adhesion and Inflammation", Cell, 56:1033-1044 (1989). Johnston et al., "Structural and Biosynthetic Studies of the Granule Membrane Protein, GMP-140, from Human Platelets and Endothelial Cells", The Journal of Biological Chemistry, 264:1-8 (1989). Johnston et al., Structure and Biosynthesis of the Platelet α-Granule Membrane Protein, GMP-140, Platelets, p. 352a, abstract #1264, Nov. 1987. Johnston et al., "Structure of the Human Gene Encoding Granule Membrane Protein-140, a member of the Selectin Family of