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Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/445
  • A61K-031/44
  • C07D-211/00
출원번호 US-0825073 (2001-04-03)
발명자 / 주소
  • Hrabie, Joseph A.
  • Keefer, Larry K.
출원인 / 주소
  • The United States of America as represented by the Department of Health and Human Services
대리인 / 주소
    Leydig, Voit & Mayer, Ltd.
인용정보 피인용 횟수 : 44  인용 특허 : 2

초록 ▼

The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine and enamine derived diazeniumdiolate

대표청구항 ▼

The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine and enamine derived diazeniumdiolate

이 특허에 인용된 특허 (2)

  1. Keefer Larry K. (Bethesda MD) Wink David A. (Frederick MD) Dunams Tambra M. (Frederick MD) Hrabie Joseph A. (Frederick MD), Antihypertensive compositions and use thereof.
    상세보기
  2. Keefer Larry K. (Bethesda MD) Hrabie Joseph A. (Frederick MD), Complexes of nitric oxide with polyamines.
    상세보기

이 특허를 인용한 특허 (44)

  1. Shami, Paul J.; Kosack, Ken M., Activated nitric oxide donors and methods of making and using thereof.
    상세보기
  2. Shami, Paul J.; Kosak, Ken M., Activated nitric oxide donors and methods of making and using thereof.
    상세보기
  3. Fossel, Eric T., Beneficial effects of increasing local blood flow.
    상세보기
  4. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  5. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  6. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  7. Stenzler, Alex, Device and method for treatment of surface infections with nitric oxide.
    상세보기
  8. Stenzler, Alex; Miller, Christopher C., Device and method for treatment of surface infections with nitric oxide.
    상세보기
  9. Stenzler, Alex; Miller, Chris C, Device and method for treatment of wounds with nitric oxide.
    상세보기
  10. Shami, Paul, In vivo use of glutathione S-transferase activated nitric oxide donors.
    상세보기
  11. Stenzler, Alex; Miller, Christopher C.; McMullin, Bevin, Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing.
    상세보기
  12. Bauman, Susanne; Stasko, Nathan A., Methods of decreasing sebum production in the skin.
    상세보기
  13. Schoenfisch, Mark; Riccio, Daniel; Nugent, Julia; Stasko, Nathan, Nitric oxide-releasing S-nitrosothiol-modified silica particles and methods of making the same.
    상세보기
  14. Hrabie, Joseph A.; Citro, Michael L.; DeRosa, Frank; Keefer, Larry K., Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof.
    상세보기
  15. Hrabie, Joseph A.; DeRosa, Frank; Keefer, Larry K., Nitric oxide-releasing diazeniumdiolated compounds.
    상세보기
  16. Hrabie, Joseph A.; Keefer, Larry K., Nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based polymers, and compositions, medical devices, and uses thereof.
    상세보기
  17. Schoenfisch, Mark H.; Shin, Jae Ho; Stasko, Nathan, Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications.
    상세보기
  18. Schoenfisch, Mark H.; Shin, Jae Ho; Stasko, Nathan, Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications.
    상세보기
  19. Schoenfisch, Mark H.; Shin, Jae Ho; Stasko, Nathan, Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications.
    상세보기
  20. Schoenfisch, Mark H.; Shin, Jae Ho; Stasko, Nathan, Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications.
    상세보기
  21. Schoenfisch, Mark H.; Shin, Jae Ho; Stasko, Nathan, Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications.
    상세보기
  22. Arnold, Ernst V.; Doletski, Blaine G.; Raulli, Robert E., Nitric oxide-releasing polymers.
    상세보기
  23. Arnold, Ernst V.; Doletski, Blaine G.; Raulli, Robert E., Nitric oxide-releasing polymers.
    상세보기
  24. Miranda, Katrina M.; Wink, David A.; Salmon, Debra J.; Basudhar, Debashree; Keefer, Larry K.; Saavedra, Joseph E.; Andrei, Daniela, Nitroxyl (HNO) releasing compounds and uses thereof in treating diseases.
    상세보기
  25. Smith, Daniel J., Stabilization and ionic triggering of nitric oxide release.
    상세보기
  26. Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
    상세보기
  27. Schoenfisch, Mark; Riccio, Daniel, Tertiary S-nitrosothiol-modified nitric—oxide-releasing xerogels and methods of using the same.
    상세보기
  28. Fossel, Eric T., Topical composition containing ibuprofen.
    상세보기
  29. Fossel, Eric T., Topical composition containing naproxen.
    상세보기
  30. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
    상세보기
  31. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
    상세보기
  32. Stasko, Nathan; Bauman, Susanne; Joshi, Pranav R., Topical gels and methods of using the same.
    상세보기
  33. Stasko, Nathan; Bauman, Susanne; Joshi, Pranav R., Topical gels and methods of using the same.
    상세보기
  34. Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
    상세보기
  35. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  36. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  37. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  38. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  39. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  40. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  41. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  42. Miller, Christopher C.; Hole, Douglas R.; Murray, Bruce R; Perry, Bryan, Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant.
    상세보기
  43. Hole, Douglas; Miller, Christopher C., Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma.
    상세보기
  44. Stasko, Nathan; Bauman, Susanne; Joshi, Pranav R., Wound dressings, methods of using the same and methods of forming the same.
    상세보기

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