초록 ▼

A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacle

A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacles. Multiple receptacles are coupled to one another by a connecting rib structure that defines straight shoulders along opposite sides of the reaction receptacle apparatus, and the shoulders support the apparatus within reaction receptacle apparatus carrying structures. A contact-limiting element holding structure for holding contact-limiting elements, such as protective tips for tubular elements, is associated with each individual receptacle and holds a contact-limiting element in an operative orientation so as to be operatively engageable by the tubular element of the substance transfer device. A receptacle apparatus manipulating structure permits the reaction receptacle apparatus to be moved from one location to another by a robotic manipulating device, and an information panel presents a surface on which human and/or machine readable information may be placed.

대표청구항 ▼

A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacle

A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacles. Multiple receptacles are coupled to one another by a connecting rib structure that defines straight shoulders along opposite sides of the reaction receptacle apparatus, and the shoulders support the apparatus within reaction receptacle apparatus carrying structures. A contact-limiting element holding structure for holding contact-limiting elements, such as protective tips for tubular elements, is associated with each individual receptacle and holds a contact-limiting element in an operative orientation so as to be operatively engageable by the tubular element of the substance transfer device. A receptacle apparatus manipulating structure permits the reaction receptacle apparatus to be moved from one location to another by a robotic manipulating device, and an information panel presents a surface on which human and/or machine readable information may be placed. composition identified by this method. A further aspect of the present invention is a method to identify a therapeutic. A further aspect of the present invention is a method of testing a therapeutic for therapeutic activity and toxicology by identifying a therapeutic using a method of the present invention and monitoring the toxicology and efficacy of the therapeutic in an in vivo model. rein the sterilant sensor includes a gas-detecting semiconductor element and a heater to elevate the temperature of the semiconductor gas-detecting element. 11. A sterilant monitoring assembly in accordance with claim 1, wherein the sterilant sensor provides output signals corresponding to detected levels of hydrogen peroxide vapor. 12. A sterilant monitoring assembly in accordance with claim 1, further comprising a temperature sensor positioned to provide output signals corresponding to detected temperature within the interior sensor chamber. 13. A sterilant monitoring assembly in accordance with claim 1, further comprising a data collection circuit operatively coupled to the sterilant sensor to receive output signals from the sterilant sensor as collected data. 14. A sterilant monitoring assembly in accordance with claim 13, wherein the data collection circuit includes an electronic memory to create a readable memory of the data collected during a selected time interval, and a signal connector to allow transfer of signals representative of the collected data from said electronic memory to a remote communication unit in communication with the signal connector. 15. A sterilant monitoring assembly in accordance with claim 13, wherein the data collection circuit includes a transmitter to transmit signals representative of the collected data to a remote communication unit. 16. A sterilization apparatus comprising: a sterilant supply conduit to supply a sterilant to a sterilization station for sterilization of at least one article; and a sterilant monitoring assembly joined in fluid communication with the sterilant supply conduit, the sterilant monitoring assembly including an external housing defining an inlet and an outlet, the external housing further defining an internal flow path therethrough for sterilant flow between the inlet and the outlet, an internal housing located within the external housing, the internal housing defining an interior sensor chamber therein, the internal housing including a valve arrangement to join the interior sensor chamber selectively in fluid communication with the internal flow path of the external housing, the valve arrangement capable of being operated between an open position and a closed position, the open position allowing sterilant to flow from the internal flow path to the interior sensor chamber, the closed position precluding the sterilant from flowing from the internal flow path to the interior sensor chamber; and a sterilant sensor positioned to provide output signals corresponding to detected levels of sterilant within the interior sensor chamber. 17. A sterilization apparatus in accordance with claim 16, wherein the internal housing of the sterilant monitoring assembly includes a base portion and a cover portion, the base portion and the cover portion mounted for relative movement therebetween to define the valve arrangement of the internal housing, at least one portion capable of being moved relative the other portion between the open position and the closed position. 18. A sterilization apparatus in accordance with claim 17, wherein the base portion of the sterilant monitoring assembly includes an isolation plate spaced from an interior surface of the exterior housing to allow sterilant flow therebetween. 19. A method of monitoring concentrations of a sterilant flowing through an apparatus, said method comprising the steps of: providing a sterilant monitoring assembly including an external housing defining an inlet and an outlet, the external housing further defining an internal flow path therethrough for sterilant flow between the inlet and the outlet, an internal housing located within the external housing, the internal housing defining an interior sensor chamber therein, the internal housing including a valve arrangement to join the interior sensor chamber selectively in fluid communication with the internal flow path of the external housing, the valve arrangement c