초록 ▼

A bone marrow collection kit is provided comprising a collection container for receiving a bone marrow containing fluid having a body that defines an interior and an inlet opening and an outlet opening and including a prefilter that extends from the outlet opening into the interior of the collection

A bone marrow collection kit is provided comprising a collection container for receiving a bone marrow containing fluid having a body that defines an interior and an inlet opening and an outlet opening and including a prefilter that extends from the outlet opening into the interior of the collection container so that fluid must flow through the prefilter to exit the collection container through the outlet opening. A first inline filter member is coupled to the outlet opening of the collection container, the first inline filter member having a flexible plastic body that defines an interior, and an inlet opening and an outlet opening and the interior including a filter so constructed and arranged that fluid that enters the inlet opening must flow through the filter to exit the first inline filter member through the outlet opening. A container for receiving a resultant filtered bone marrow containing fluid having an interior in fluid communication with the outlet opening of the first inline filter member is also provided. Methods for processing the bone marrow and constructing the inline filter are also provided.

대표청구항 ▼

1. An inline filter for filtering biological suspensions comprising: a body defined by two flexible sheets of plastic sealed along edges thereof to form an interior having an inlet and an outlet opening; and a filter comprising a screen that is sealed along the edges of the sheets so as to exten

1. An inline filter for filtering biological suspensions comprising: a body defined by two flexible sheets of plastic sealed along edges thereof to form an interior having an inlet and an outlet opening; and a filter comprising a screen that is sealed along the edges of the sheets so as to extend across and for an entire length of the interior and divide the interior into a first section and a second section, the screen being so located that the inlet opening is in the first section and the outlet opening is in the second section and fluid entering the interior from the inlet must flow through the screen prior to entering the outlet opening. 2. The inline filter of claim 1 wherein the screen is constructed from a fluorocarbon plastic. 3. The inline filter of claim 1 wherein the plastic comprises polyvinyl chloride. 4. The inline filter of claim 1 wherein the body and the screens each have a circular cross-sectional shape. 5. The inline filter of claim 1 wherein the body and the screens each have a square cross-sectional shape. 6. The inline filter of claim 1 wherein the biological suspension is a bone marrow containing fluid. 7. The inline filter of claim 1 wherein the two flexible sheets are sufficiently flexible to allow manual manipulation of the filter through the sheets. 8. The inline filter of claim 1 wherein the two flexible sheets have a thickness of approximately 0.005 inches to approximately 0.030 inches. 9. A method for manufacturing an inline filter comprising the steps of: placing a screen between two sheets of a plastic material; sealing the sheets of plastic together along a resultant seal line having a width to seal edges thereof to create an interior including the screen and to trap a perimeter of the screen within a portion of the width of the resultant seal line between the sheets of plastic so that the screen extends across the entire interior, the screen not extending for the entire width of the resultant seal line; and locating an inlet opening and an outlet opening on opposite sides of the screen. 10. The method of claim 9 wherein the screen is constructed from a fluorocarbon plastic. 11. The method of claim 9 wherein the plastic sheets are constructed from polyvinyl chloride. 12. The method of claim 9 wherein the sheets are R/F welded together. 13. The method of claim 9 including the step of sterilizing the inline filter using radiation. 14. The method of claim 9 wherein the screen is insert molded creating a plastic frame around the screen. 15. An inline filter for filtering a biological fluid comprising: a body constructed from a polyvinyl chloride containing flexible plastic material and having a first side, a second side, and defining an interior having an inlet and an outlet opening; and a filter screen that is sealed within the interior along a seal line between the first side and second side of the body to create the interior, a perimeter of the screen being trapped within a portion of the width of the seal line between the first side and second side of the flexible plastic so that the screen extends across an entire length and width of the interior, the screen does not extend for the entire width of the seal line. 16. The inline filter of claim 15 wherein the body and the filter screen each have a circular cross-sectional shape. 17. The inline filter of claim 15 wherein the body and the filter screen each have a square cross-sectional shape. 18. The inline filter of claim 15 wherein the first and second sides comprise separate sheets of flexible plastic. 19. The inline filter of claim 15 wherein the biological suspension is a bone marrow containing fluid. 20. The inline filter of claim 15 wherein the flexible plastic is sufficiently flexible to allow manual manipulation of the filter screen through the sheets. 21. The inline filter of claim 15 wherein the filter screen is constructed from a fluorocarbon plastic.