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A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-she

A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-sheet layers sintered together. The substantially monolithic structure has defined therein a means for heating the DNA amplification chamber and a means for cooling the DNA amplification chamber. The means for heating and means for cooling operate to cycle the temperature of the DNA amplification chamber as required for performing a DNA amplification process, such as PCR.

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A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-she

A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-sheet layers sintered together. The substantially monolithic structure has defined therein a means for heating the DNA amplification chamber and a means for cooling the DNA amplification chamber. The means for heating and means for cooling operate to cycle the temperature of the DNA amplification chamber as required for performing a DNA amplification process, such as PCR. Hearts Preserved with University of Wisconsin Solution", Circulation, Supplement II, (Nov. 1992) pp. II-333-II-338, vol. 86, No. 5. A. G. Upadhya Et Al., "Evidence of a Role for Matrix Metalloproteinases in Cold Preservation Injury of the Liver in Humans and in the Rat", Hepatology (1997), vol. 20, No. 4. G. A. Upadhya and S. M. Strasberg, "Glutathione, Lactobionate, and Histidine: Cryptic Inhibitors of Matrix Metalloproteinases Contained in University of Wisconsin and Histidine/Tryptophan/Ketoglutarate Liver Preservation Solutions", Hepatology (May 2000) pp. 1115-1121, vol. 31, No. 5.