초록 ▼

A device and method for providing a suspended agent such as a contrast agent without mechanical resuspension. A volume of agent is divided into sub-volumes in a network of tubes, cells, sponges, grooves, etc. A propellant fluid flows through the network to release the suspended agent. The network ma

A device and method for providing a suspended agent such as a contrast agent without mechanical resuspension. A volume of agent is divided into sub-volumes in a network of tubes, cells, sponges, grooves, etc. A propellant fluid flows through the network to release the suspended agent. The network may be internal to a container for the propellant fluid. Alternatively, the network may be adjacent an exit port of a container for the propellant fluid, or may be in-line between a propellant fluid container and a patient. The invention reduces sedimentation of agents into one or a few aggregates and eliminates a mechanical mixing step. The invention thus provides a uniformly suspended agent, improving patient health and safety and increasing cost and time savings.

대표청구항 ▼

1. A device for providing a volume of an agent with a propellant fluid, comprising: a single syringe consisting of a side wall defining an interior space, an exit port, a plunger positioned in the interior space and having a sealing engagement with the side wall, the entire interior space between

1. A device for providing a volume of an agent with a propellant fluid, comprising: a single syringe consisting of a side wall defining an interior space, an exit port, a plunger positioned in the interior space and having a sealing engagement with the side wall, the entire interior space between The plunger and the exit port containing the propellant fluid, and the plunger being movable in the interior space toward the exit port, and a helical tubular body defining a continuously open and uninterrupted fluid passageway within said interior space of said syringe, said helical tubular body being located between said plunger and said exit port and containing an agent, the fluid passageway having an outlet coupled in fluid communication with said exit port of said syringe and an inlet opening into said interior space, the inlet receiving propellant fluid when the plunger is moved so that the propellant fluid flows through said fluid passageway in direct contact with the agent and said outlet directing the agent contacted by the flow of the propellant fluid to said exit port. 2. The device of claim 1 wherein said agent is an imaging contrast agent. 3. The device of claim 1 wherein said agent is a microbubble preparation. 4. The device of claim 1 wherein said agent is a colloid. 5. The device of claim 1 wherein said propellant fluid is biocompatible. 6. The device of claim 1 wherein said passageway has a helical configuration. 7. A device for providing a volume of an agent with a propellant fluid, comprising: only one syringe, said syringe having a side wail defining an interior space, an exit port, and a plunger positioned in the interior space and having a sealing engagement with the side wall, the entire interior space between the plunger and the exit port containing the propellant fluid, and the plunger being movable in the interior space toward the exit port, and a helical tubular body defining a continuously open and uninterrupted fluid passageway within said interior space of said syringe, said helical tubular body being located between said plunger and said exit port and containing the agent, the fluid passageway having an outlet coupled in fluid communication with said exit port of said syringe and an inlet opening into said interior space, the inlet receiving propellant fluid when the plunger is moved so that the propellant fluid flows through said fluid passageway in direct contact with the agent and said outlet directing the agent contacted by the flow of the propellant fluid to said exit port.