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Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-013/00
  • A61L-015/00
출원번호 US-0737829 (2000-12-14)
발명자 / 주소
  • Luo, Eric C.
  • Hsu, Tsung-Min
출원인 / 주소
  • Dermatrends, Inc.
대리인 / 주소
    Reed, Dianne E.Eberle, Shelley P.Reed & Eberle LLP
인용정보 피인용 횟수 : 21  인용 특허 : 36

초록 ▼

A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered androgenic drugs. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the androgenic drug through a body surface while m

대표청구항 ▼

A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered androgenic drugs. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the androgenic drug through a body surface while m

이 특허에 인용된 특허 (36)

  1. Mantelle Juan A. (Miami FL), Compositions and methods for topical administration of pharmaceutically active agents.
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  2. Schmirler Dennis Lee ; Portman Edward Malcolm ; Christensen Michael S., Compositions, methods and devices for the transdermal delivery of drugs.
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  3. Oloff Horst (Berlin DEX) Tack Johannes-Wilhelm (Berlin DEX) Windt Fred (Berlin DEX) Zimmermann Ingfried (Berlin DEX), Device for transdermal administration of active medicinal agents.
    상세보기
  4. Therriault Donald J. (York PA) Rodgers Kenneth W. (York PA), Drug flux enhancer-tolerant pressure sensitive adhesive composition.
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  5. Ron Eyal S. ; Bromberg Lev ; Temchenko Marina, End modified thermal responsive hydrogels.
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  7. Scholz Matthew T. ; Asmus Robert A. ; Hedenstrom John C., Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents.
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  8. Yamanaka Akihito,JPX ; Kinoshita Takashi,JPX ; Sunami Masaki,JPX, Medicated plaster containing basic physiologically active agents and/or salts thereof.
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  9. Ebert Charles D. (Salt Lake City UT) Patel Dinesh (Murray UT) Heiber Werner (Salt Lake City UT), Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective level.
    상세보기
  10. Foldvari Marianna,CAX, Method for preparing biphasic multilamellar lipid vesicles.
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  11. Curtis Ernest S. ; Kalafsky Robert ; Kaplan Elinor R., Method of treating the skin with organic acids in anhydrous microsphere delivery systems.
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  12. Parab Prakash ; Yu Cheng Der Tony ; Patel Bhiku, Methods and compositions for enhancing skin permeation of drugs using permeation enhancers, when drugs and/or permeation enhancers are unstable in combination during long-term storage.
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  13. Lee Vincent H. (Monterey Park CA) Yen Wan-Ching (Columbus OH), Methods and compositions to enhance epithelial drug transport.
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  14. Ebert Charles D. (Salt Lake City UT) Patel Dinesh C. (Murray UT) Mazer Norman A. (Salt Lake City UT) Venkateshwaran Srinivasan (Salt Lake City UT), Methods for providing testosterone and optionally estrogen replacement therapy to women.
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  15. Yamazaki Chika,JPX ; Sato Tadao,JPX ; Nagano Tatsuo,JPX, Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof.
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  16. Ptchelintsev Dmitri ; Scancarella Neil ; Kalafsky Robert, Oxa acids and related compounds for treating skin conditions.
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  17. Ptchelintsev Dmitri ; Scancarella Neil ; Kalafsky Robert, Oxa diacids and related compounds for treating skin conditions.
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  18. Wolter Karin (Melsbach DEX) Mller Walter (Neuwied DEX) Simon Gnter (Hillesheim DEX) Nalbach Christa (Leutesdorf DEX) Hoffmann Hans-Rainer (Neuwied DEX), Patch for transdermal administration of volatile pharmaceutically active ingredients of chemically basic nature and a pr.
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  19. Lerner E. Itzhak,ILX ; Rosenberger Vered,ILX ; Flashner Moshe,ILX, Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity.
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  20. Venkateshwaran Srinivasan ; Fikstad David ; Ebert Charles D., Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
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  21. Scarborough Robert M. ; Zhu Bing-Yan ; Su Ting, Selective factor Xa inhibitors.
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  22. Miranda Jesus (Miami FL) Sablotsky Steven (Miami FL), Solubility parameter based drug delivery system and method for altering drug saturation concentration.
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  23. Perricone Nicholas V., Topical administration of catecholamines and related compounds to subcutaneous muscle tissue using percutaneous penetra.
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  24. Durif Franck (Durtol FRX) El-Rashidy Ragab (Deerfield IL), Transdermal administration of apomorphine.
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  25. Durif Franck,FRX ; El-Rashidy Ragab, Transdermal administration of apomorphine.
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  26. Lhila Ramesh (South Windsor CT) Ganslaw Stuart (Simsbury CT) Serra Eleanor (West Springfield MA), Transdermal delivery of appetite suppressant drug.
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  27. Hedenstrom John C. ; Husberg Michael L. ; Wilking Shari L. ; Scholz Matthew T., Transdermal device for the delivery of testosterone.
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  28. Lee Eun S. (Redwood City CA) Yum Su I. (Los Altos CA), Transdermal drug delivery device.
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  29. Song Suk-Zu (Flanders NJ) Mehta Surendra C. (Randolph NJ) Rashidbaigi Zahra A. (Nutley NJ) Nesbitt Russell U. (Somerville NJ) Fawzi Mahdi B. (Flanders NJ), Transdermal matrix system.
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  30. Therriault Donald J. ; Zajaczkowski Michael J. ; Stutzman Barbara A., Transdermal pressure sensitive adhesive drug delivery system.
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  31. Gupte Arun R. (Ingelheim am Rhein DEX) Rohr Uwe (Gau Algesheim DEX) Zierenberg Bernd (Bingen DEX), Transdermal system for the administration of pharmacological compounds under pH-controlled conditions.
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  32. Yamada Masayuki (Kawanishi JPX) Nonomura Muneo (Suita JPX) Nishikawa Kohei (Kyoto JPX), Transdermal therapeutic composition.
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  33. Campbell Patricia S. (Palo Alto CA) Eckenhoff James B. (Los Altos CA), Transdermal therapeutic system having improved delivery characteristics.
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  34. Majeti Satyanarayana (Cincinnati OH), Treatment of nicotine craving and/or smoking withdrawal symptoms.
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  35. Sawanishi Hiroyuki (Kanazawa JPX) Ito Yasuo (Katsuyama JPX) Kato Hideo (Fukui JPX) Koshinaka Eiichi (Katsuyama JPX) Ogawa Nobuo (Katsuyama JPX) Morikawa Kouji (Katsuyama JPX), Tricyclic compounds and method for treating allergic diseases.
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  36. Hsu Tsung-Min ; Chen Tung Fen, Two-phase matrix for sustained release drug delivery device.
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  1. Bar-Or, David, Method for treatment of diseases.
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  2. Bar-Or, David, Method for treatment of diseases.
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  3. Bar-Or, David, Methods and products for treatment of diseases.
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  4. Bar-Or, David, Methods and products for treatment of diseases.
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  5. Bar-Or, David, Methods of treatment of diseases.
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  6. Bar-Or, David, Methods of treatment of diseases.
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  7. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
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  8. Dudley, Robert E.; Drouin, Dominique, Pharmaceutical composition and method for treating hypogonadism.
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  9. Crowley, Michael M.; Keen, Justin M.; Koleng, John J.; Zhang, Feng, Process for the preparation of a hot-melt extruded laminate.
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  10. Crowley, Michael M.; Keen, Justin M.; Koleng, John J.; Zhang, Feng, Stabilized compositions containing alkaline labile drugs.
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  11. Crowley, Michael M.; Keen, Justin M.; Koleng, John J.; Zhang, Feng, Stabilized compositions containing alkaline labile drugs.
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  12. Crowley, Michael M.; Keen, Justin M.; Koleng, John J.; Zhang, Feng, Stabilized compositions containing alkaline labile drugs.
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  13. Crowley, Michael W.; Keen, Justin M.; Koleng, John J.; Zhang, Feng, Stabilized compositions containing alkaline labile drugs.
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  14. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
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  15. Malladi, Ramana; Miller, Jodi, Testosterone gel and method of use.
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  16. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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  17. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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  18. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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  19. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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  20. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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  21. Malladi, Ramana; Stahlman, Jodi, Testosterone gel and method of use.
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