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Chewable tablets containing mannitol and Aspartame 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/46
  • A61K-009/20
출원번호 US-0811494 (2001-03-19)
발명자 / 주소
  • Valentine, William
  • Valentine, William K.
출원인 / 주소
  • Advanced Technology Pharmaceuticals Corporation
대리인 / 주소
    DeLio & Peterson, LLC
인용정보 피인용 횟수 : 31  인용 특허 : 24

초록

Chewable tablets and particulate food and pharmaceutical products are disclosed which are made from agglomerates comprising an alcohol sugar such as mannitol and a high intensity sweetener such as Aspartame from which agglomerate tablets may be directly compressed, and processes for making the agglo

대표청구항

1. A chewable tablet containing an intense sweetener comprising a compressed particulate agglomerate, wherein the agglomerate comprises, by weight, about 80% to about 97% of an alcohol sugar, about 1% to 10% high intensity sweetener and up to about 10% binder, and the particulate agglomerate has voi

이 특허에 인용된 특허 (24)

  1. Chavkin Leonard ; Mackles Leonard, Chewable molded tablet containing medicinally active substances.
  2. Valentine William (Lawrenceville GA) Valentine William K. (Lawrenceville GA), Defoaming composition.
  3. Gole Dilip J. (Ann Arbor MI) Levinson R. Saul (Saline MI) Carbone James (Belleville MI) Davies J. Desmond (Grosse Pointe Farms MI), Delivery matrices prepared by solid-state dissolution.
  4. Serpelloni Michel (Beuvry les Bethune FRX) Croisier Alain (Locon FRX), Directly compressible pulverulent composition and a process for obtaining the same.
  5. Cherukuri Subraman R. (10 Jean Dr. Towaco NJ 07082) Raman Krishna P. (5 Marre Dr. Randolph NJ 07869) Mansukhani Gul (97 Petrus Ave. Staten Island NY 10312) Orama Angel M. (19 Elizabeth Ave. Stanhope , Encapsulated flavor with bioadhesive character in pressed mints and confections.
  6. Makino Tadashi,JPX ; Yamada Masayuki,JPX ; Kikuta Jun-ichi,JPX, Fast dissolving tablet and its production.
  7. Iles Martin C. (7 Cartwright Drive Shaw ; Swindon ; Wiltshire GBX) Atherton Angela D. (170 ; Windsor Drive Chelsfield ; Orpington ; Kent GBX) Copping Neil M. (8 Lautrec Way Haydon Hill ; Aylesbury ; , Freeze-dried dosage forms and methods for preparing the same.
  8. Upson James G. (Springdale OH) Russell Carmelita M. (Cincinnati OH), Ingestible pharmaceutical compositions for treating upper gastrointestinal tract distress.
  9. Eoga Anthony B. ; Valia Kirti H., Method for making fast-melt tablets.
  10. Hayward Marshall,GBX, Palatable pharmaceutical compositions.
  11. Serpelloni Michel (Beuvry les Bethune FRX) Croisier Alain (Locon FRX), Partially melt co-crystallized xylitol/sorbitol and a process for obtaining the same.
  12. Reiner Alberto,ITX ; Seneci Alessandro,ITX, Pharmaceutical compositions based on chewing gum and a method for the preparation thereof.
  13. Bolt Ian James,GBX ; Merrifield David Roy,GBX ; Carter Paul Laurence,GBX, Pharmaceutical formulation with effervescent couple.
  14. Courteille Frdric (Cachan FRX) Vanhoeve Magali (Savigny s/Orge FRX), Porous pharmaceutical form and its preparation.
  15. Seyffert Ina,DEX ; Uhlemann Hans,DEX ; Walter Reinhard,DEX ; Maasz Joachim Martin, Process and apparatus for the agglomeration of hydrolytically sensitive substances by means of steam.
  16. Fuisz Richard C. ; Cherukuri Subraman R. ; Kota Suresh B. ; Stewart James L., Process for forming chewable quickly dispersing multi-vitamin preparation and product therefrom.
  17. Serpelloni Michel (Beuvry les Bethune FRX) Boonaert Jean-Philippe (Laventie FRX), Pulverulent mannitol of moderate friability and process for its preparation.
  18. Valentine William (Rocky Hill CT), Quick-liquifying, chewable tablet.
  19. Pebley Walter S. (Albany OR) Jager Norman E. (Albany OR) Thompson Sally J. (Albany OR), Rapidly distintegrating tablet.
  20. Roche, Edward J.; Reo, Joseph P., Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets.
  21. Juch Rolf-Dieter (Wangen CHX) Birrenbach Gerd (Kappel CHX) Pflugshaupt Christian (Haegendorf CHX), Solid, fast-soluble pharmaceutical preparation containing S-(carboxymethyl)-L-cysteine and/or N-acetylcysteine.
  22. Tsau Josef H. (Skokie IL) Damani Nalinkant C. (Cincinnati OH), Taste masking compositions.
  23. Mehta Atul M. (Ramsey NJ), Taste-masked pharmaceutical compositions.
  24. Kuncewitch Thomas J. (Long Valley NJ) Silva Jose (Woodside NY) Orlandi Daniel A. (Flushing NY) Glass Michael (Fairlawn NJ) Zamudio-Tena Jose F. (Morristown NJ), Zein as a moisture barrier for sugarless edible compositions and method for preparing same.

이 특허를 인용한 특허 (31)

  1. Pearson, Matthew M.; Valentine, William; Valentine, William K., (citric) acid/maltodextrin co-agglomerate.
  2. Dewis, Mark L.; Huber, Michelle E.; Cossette, Michael V.; Agyemang, David O.; Conklin, Garry; Pei, Tao, Alkyldienamides exhibiting taste and sensory effect in flavor compositions.
  3. Dewis,Mark L.; Huber,Michelle E.; Cossette,Michael V.; Agyemang,David O., Alkyldienamides exhibiting taste and sensory effect in flavor compositions.
  4. Prakash, Indra; DuBois, Grant E., Condiments with high-potency sweetener.
  5. Dewis,Mark L.; John,Thumplasseril V.; Eckert,Markus A.; Colstee,Jan Herman; Da Costa,Neil C.; Pei,Tao, Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof.
  6. John, Thumplasseril V.; Eckert, Markus A.; Dewis, Mark L.; Colstee, Jan Herman; da Costa, Neil C., Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof.
  7. Dewis,Mark L.; Huber,Michelle E., E2, E4, Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same.
  8. Dewis,Mark L.; Huber,Michelle E., E2,E4,Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same.
  9. Stella, Mark Edward; Entwisle, John Richard; Newlon, Jason William; Naykki, Christine Louis, Effervescent dosage form.
  10. Stella, Mark Edward; Entwisle, John Richard; Newlon, Jason William; Naykki, Christine Louis, Effervescent dosage form.
  11. Venkatesh, Gopi M.; Vishnupad, Krishna S.; Percel, Phillip J., Extended release dosage forms of propranolol hydrochloride.
  12. Mapelli, Luigi; Fabiani, Flavio; Boltri, Luigi; Gatti, Paolo; Serratoni, Mauro; Cassanmagnago, Roberto, Fexofenadine microcapsules and compositions containing them.
  13. Mapelli, Luigi; Fabiani, Flavio; Boltri, Luigi; Gatti, Paolo; Serratoni, Mauro; Cassanmagnago, Roberto, Fexofenadine microcapsules and compositions containing them.
  14. Mapelli, Luigi; Fabiani, Flavio; Boltri, Luigi; Gatti, Paolo; Serratoni, Mauro; Cassanmagnago, Roberto, Fexofenadine microcapsules and compositions containing them.
  15. Prakash, Indra; DuBois, Grant E., High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith.
  16. Ohta, Motohiro; Hayakawa, Eiji; Ito, Kunio; Tokuno, Sanji; Morimoto, Kiyoshi; Watanabe, Yasushi, Intrabuccally rapidly disintegrating tablet and a production method of the tablets.
  17. Ohta, Motohiro; Hayakawa, Eiji; Ito, Kunio; Tokuno, Sanji; Morimoto, Kiyoshi; Watanabe, Yasushi, Intrabuccally rapidly disintegrating tablet and a production method of the tablets.
  18. Ohta, Motohiro; Hayakawa, Eiji; Ito, Kunio; Tokuno, Sanji; Morimoto, Kiyoshi; Watanabe, Yasushi, Intrabuccally rapidly disintegrating tablet and a production method of the tablets.
  19. Dewis, Mark L.; Huber, Michelle E.; Cossette, Michael V., Menthyl half acid ester derivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials.
  20. Venkatesh, Gopi M.; Harmon, Troy M.; Taylor, John, Orally disintegrating tablets of atomoxetine.
  21. Dewis, Mark L.; Conkiln, Garry; Pei, Tao; Smith, Catherine Marie; Janczuk, Adam Jan, Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions.
  22. Dewis,Mark L.; Conklin,Garry; Pei,Tao, Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions.
  23. Venkatesh, Gopi M., Taste-masked pharmaceutical compositions.
  24. Venkatesh, Gopi M., Taste-masked pharmaceutical compositions.
  25. Venkatesh, Gopi M., Timed, pulsatile release systems.
  26. Venkatesh, Gopi M., Timed, pulsatile release systems.
  27. Venkatesh, Gopi M., Timed, pulsatile release systems.
  28. Venkatesh, Gopi M., Timed, pulsatile release systems.
  29. Venkatesh, Gopi M., Timed, pulsatile release systems.
  30. Percel, Phillip J.; Vishnupad, Krishna S.; Venkatesh, Gopi M., Timed, sustained release systems for propranolol.
  31. Percel, Phillip J.; Vishnupad, Krishna S.; Venkatesh, Gopi M., Timed, sustained release systems for propranolol.
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