초록 ▼

A hemofiltration system is provided in which ultrafiltrate is purified by reverse osmosis for reinfusion. Non-sterile infusate concentrate is dialyzed into the purified ultrafiltrate and combined with cleared blood which is returned to the patient. In another system, a hemofilter is used to steriliz

A hemofiltration system is provided in which ultrafiltrate is purified by reverse osmosis for reinfusion. Non-sterile infusate concentrate is dialyzed into the purified ultrafiltrate and combined with cleared blood which is returned to the patient. In another system, a hemofilter is used to sterilize essentially pure, non-sterile water for dilution of sterile infusate concentrate, then the hemofilter is used to filter blood, the infusate concentrate being combined with cleared blood for return to the patient.

대표청구항 ▼

1. A system for processing blood from an individual comprising a draw path coupled to the individual to convey blood from the individual, a blood treatment unit communicating with the draw path comprising a hemofiltration membrane operating to remove waste fluid comprising water and at least one

1. A system for processing blood from an individual comprising a draw path coupled to the individual to convey blood from the individual, a blood treatment unit communicating with the draw path comprising a hemofiltration membrane operating to remove waste fluid comprising water and at least one ionic species from the blood, a waste outlet operating to convey the waste fluid from the blood treatment unit, and a treated blood outlet operating to convey treated blood from the blood treatment unit following removal of the waste fluid, a non-sterile source of at least one replacement ionic species, a replacement fluid generation assembly comprising a waste treatment unit coupled to the waste outlet operating to remove ionic species from the waste fluid to create essentially pure sterile water, and a pure water outlet operating to convey the essentially pure sterile water from the waste treatment unit, and a replenishment unit coupled to the pure water outlet and the non-sterile source and including a semipermeable membrane to convey by ionic transport the at least one replacement ionic species from the non-sterile source into the essentially pure sterile water to form an essential sterile replacement fluid, and a replacement fluid outlet operating to convey the essentially sterile replacement fluid from the replenishment unit, and a return path coupled to the individual and communicating with the treated blood outlet and the replenishment fluid outlet to convey treated blood and the essentially sterile replacement fluid to the individual. 2. A system for processing blood from an individual comprising a draw path coupled to the individual to convey blood from the individual, a blood treatment unit communicating with the draw path comprising a hemofiltration membrane operating to remove waste fluid comprising water and at least one ionic species from the blood, a waste outlet operating to convey the waste fluid from the blood treatment unit, and a treated blood outlet operating to convey treated blood from the blood treatment unit following removal of the waste fluid, a sterile source of at least one replacement ionic species, a replacement fluid generation assembly comprising a waste treatment unit coupled to the waste outlet operating to remove ionic species from the waste fluid to create essentially pure sterile water, and a pure water outlet operating to convey the essentially pure sterile water from the waste treatment unit, and a replenishment unit coupled to the pure water outlet and the sterile source and including a semipermeable membrane to convey by ionic transport the at least one replacement ionic species from the sterile source into the essentially pure sterile water to form an essential sterile replacement fluid, and a replacement fluid outlet operating to convey the essentially sterile replacement fluid from the replenishment unit, and a return path coupled to the individual and communicating with the treated blood outlet and the replenishment fluid outlet to convey treated blood and the essentially sterile replacement fluid to the individual. 3. A system according to claim 1 or 2 wherein the waste treatment unit includes a reverse osmosis membrane.