A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): AmB(1-m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or
A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): AmB(1-m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or larger and smaller than 1: wherein n has a value of 0 to 10, k has a value of 3 or 5, and R is at least one group selected from the group consisting of groups represented by General Formulae (5) to (7): in Formula (5) R1 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and q is an integer selected from 1 to 8; in Formula (6) R2 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and r is an integer selected from 1 to 8; in Formula (7) R3 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and s is an integer selected from 1 to 8. The efficient production methods are also provided.
대표청구항▼
A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): AmB(1-m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or
A polyhydroxyalkanoate having a monomer unit composition represented by General Formula (1): AmB(1-m) (1) wherein A is represented by General Formula (2), B is at least one selected from the group consisting of monomer units represented by General Formula (3) or (4), and m has a value of 0.01 or larger and smaller than 1: wherein n has a value of 0 to 10, k has a value of 3 or 5, and R is at least one group selected from the group consisting of groups represented by General Formulae (5) to (7): in Formula (5) R1 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and q is an integer selected from 1 to 8; in Formula (6) R2 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and r is an integer selected from 1 to 8; in Formula (7) R3 is a group selected from the group consisting of a hydrogen atom (H), halogen atoms, --CN, --NO2,--CF3,--C2F5and --C3F7; and s is an integer selected from 1 to 8. The efficient production methods are also provided. ethanolamine coupled through a lipid amine group. 13. A composition according to claim 8, wherein said lipid is a phospholipid having two acyl carbon chains which have at least one unsaturated bond. 14. A composition according to claim 8, wherein said lipid is a phospholipid having two acyl carbon chains, said acyl carbon chains being saturated. 15. A composition according to claim 8, wherein B is a phosphatidylethanolamine coupled through a lipid amine group, n is 8 and m is 4. 16. A composition according to claim 5, wherein said liposome contains about 10 to 40 mole percent cholesterol, about 40 to 85 mole percent of a neutral phospholipid, and about 5 to 15 mole percent of a phospholipid derivatized with a compound having the formula wherein: R1is member selected from the group consisting of hydrogen and alkyl; A is a member selected from the group consisting of hydrogen, alkyl, acyl and a ligand; or, optionally, R1,A, and the nitrogen to which they are bound form an azido moiety; R2is a member of the group selected from hydrogen, optionally substituted alkyl, optionally substituted aryl and a side chain of an amino acid; B is a member selected from the group consisting of hydrogen, halogen, hydroxy, alkoxy, amino, NR4R5wherein R4and R5are independently hydrogen or alkyl, mercapto, hydrazino, diacylglycerolyl, dialkylglycerolyl, N,N-dialkylamino, 1,2-diacyloxy-3-aminopropane, 1,2-dialkyloxy-3-aminopropane and a ligand; n is 4 to 80; m is 2 to 6; p is 1 to 4; and q is 0 or 1. 17. A composition according to claim 5, wherein said liposome contains one or more bioactive agents. 18. A composition according to claim 17, wherein said bioactive agent is an anti-tumor compound. 19. A composition according to claim 17, wherein said bioactive agent is a gene construct or an oligonucleotide for therapeutic use. 20. A composition according to claim 8, wherein B is coupled via an esterase- or peptidase-sensitive linkage. 21. A composition according to claim 5, wherein said liposome comprises a surface-bound ligand which is effective to bind specifically and with high affinity to ligand-binding molecules carried on the surface of specific cells. 22. A composition according to claim 21, wherein said surface-bound ligand is an antibody effective to bind specifically and with high affinity to an antigen which is expressed in a cell in a disease state. 23. A lipid-based composition comprising a steric barrier of defined length. 24. A composition according to claim 23 wherein said steric barrier is a compound of Formula II: wherein: R1is member selected from the group consisting of hydrogen and alkyl; R2is a member of the group selected from hydrogen, optionally substituted alkyl, optionally substituted aryl and a side chain of an amino acid; A is a member selected from the group consisting of hydrogen, alkyl, acyl and a ligand; or, optionally, R1,A, and the nitrogen to which they are bound form an azido moiety; B is a member selected from the group consisting of hydrogen, halogen, hydroxy, alkoxy, amino, NR4R5,wherein R4and R5are independently hydrogen or alkyl, mercapto, hydrazino, diacylglycerolyl, dialkylglycerolyl, N,N-dialkylamino, 1,2-diacyloxy-3-aminopropane, 1,2-dialkyloxy-3-aminopropane, and a ligand; n is 4 to 80; m is 2 to 6; p is 1 to 4; and q is 0 or 1. 25. A composition comprising a compound of Formula IV: wherein: A is selected from the group consisting of hydrogen, alkyl, acyl and a ligand; R1and R2are independently selected from the group consisting of hydrogen and alkyl; R6and R7are independently selected from the group consisting of hydrogen, optionally substituted alkyl and optionally substituted aryl, wherein the substituents include aryl, amine, carboxyl, thiol and hydroxy groups; B is a me
Anderson Alistair J. (Hull GB2) Dawes Edwin A. (Humberside GB2) Haywood Geoffrey W. (Hull GB2) Byrom David (Cleveland GB2), Microbiological production of polyesters having C8and/or C10monomer repeat units.
Holmes Paul A. (Middlesbrough GB2) Willmouth Frank M. (Royston GB2) Newton Alan B. (Welwyn Garden City GB2), Polymer blends containing polymer of b
상세보기
Witholt Bernard (Eelde NLX) Lageveen Roland G. (Groningen NLX), Process for producing polyesters by fermentation: a process for producing optically active carboxylic acids and esters:.
Nomoto, Tsuyoshi; Yano, Tetsuya, Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same.
Nomoto, Tsuyoshi; Yano, Tetsuya, Isogenic strain line of bacterium for producing polyhydroxyalkanoate in which polyhydroxyalkanoate synthase gene is disrupted and method for producing polyhydroxyalkanoate using the same.
Kenmoku,Takashi; Sugawa,Etsuko; Yano,Tetsuya; Imamura,Takeshi; Honma,Tsutomu, Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule.
Kenmoku,Takashi; Yano,Tetsuya; Mihara,Chieko; Kozaki,Shinya; Honma,Tsutomu; Fukui,Tatsuki; Imamura,Takeshi; Sugawa,Etsuko, Polyhydroxy alkanoate copolymer including within molecule unit having vinyl group or carboxyl group in side chain, and producing method therefor.
Honma,Tsutomu; Kozaki,Shinya; Imamura,Takeshi; Kenmoku,Takashi; Fukui,Tatsuki; Sugawa,Etsuko; Yano,Tetsuya, Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same.
Kozaki,Shinya; Honma,Tsutomu; Yano,Tetsuya, Polyhydroxyalkanoate synthesizing microorganism and process of producing polyhydroxyalkanoate using the same.
Fukui,Tatsuki; Yano,Tetsuya; Mihara,Chieko; Kozaki,Shinya; Honma,Tsutomu; Kenmoku,Takashi, Polyhydroxyalkanoate, process for preparing the same, and resin composition containing the polyhydroxyalkanoate.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.