Topical application of stable hydroalcoholic compositions for maintaining or improving skin conditions, and delivering fragrance to skin
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IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-025/00
A61K-007/00
A61K-007/40
C11D-013/00
출원번호
US-0075893
(2002-02-14)
발명자
/ 주소
Scholz, Matthew T.
Asmus, Robert A.
Charpentier, Jill R.
출원인 / 주소
3M Innovative Properties Company
대리인 / 주소
Lambert, Nancy M.
인용정보
피인용 횟수 :
48인용 특허 :
52
초록▼
Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thi
Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23° C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.
대표청구항▼
Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thi
Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23° C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation. d 5-bromovinyldeoxyuridine. 4. The method of claim 1, wherein said target cells are selected from the group consisting of tumor cells and virally infected cells. , 6: 639-646 (1987). Kim, et al., "The Influence of Enzymes and Inflammation on Absorption of Experimentally Induced Vitreous Hemorrhage", Dept. of Ophthalmology, Korea Univ. Medical Journal, 9(1):87-97 (1972). 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Results and Complications of Pars Plana Vitrectomy", Archives of Ophthalmology, 98 : 1248-1252 (1980). Gibbons, et al., "Retinal Damage from Suprathreshold Q-switch Laser Exposure", Health Physics, 35 : 461-469 (1978). Greer, et al., "A Study of Stimulated Vitreous Hemorrhage Using Labeled Blood", Archives of Ophthalmology, 79: 755-758 (1968). Holmes,e t al., "Intravitreal Urokinase in the Management of Vitreous Haemorrhage", Transcript of Ophthalmological Socities of the United Kingdom, 94: 591-596 (1974). Koziol, et al., "Urokinase in Experimental Vitreous Hemorrhage", Ophthalmic Surgery, 6 : 79-82 (1975). Maberley, et al., "The Effect of a Fibrinolytic Agent on Vitreous Hemorrhage in Rabbits", Canadian Journal of Ophthalmology, 5: 55-63 (1970). Machemer, et al., "Pars Plana Vitrectomy", Transactions of the American Academy of Ophthalmology and Otolary ngology, 81: 350-351 (1976). Machemer, et al., "A New Concept for Vitreous Surgery, Indications and Results", American Journal of Ophthalmology, 74 : 1034-1056 (1972). Mandelcorn, et al., "Pars Plana Vitrectomy for the Mangement of Severe Diabetic Retinopathy", American Journal of Ophthalmology, 81 : 561-570 (1976). Peyman, et al., "One Hundred Consecutive Pars Plana Vitrectomies Using the Vitrophage", American Journal of Ophthalmology, 81 : 263-271 (1976). Pierse, et al., "Urokinase in Ophthalmology", LANCET, 2: 1143-1144 (1963). Pierse, et al., "Use of Urokinase in the Anterior Chamber of the Eye", Journal of Clinical Pathology, 17:362 (1964). Rakusin, et al., "Urokinase in the Treatment of Traumatic Hyphaema", British Journal of Ophthalmology, 55:826-832 (1971). Tow, et al., "Urokinase in Pulmonary Embolism", New England Journal of Medicine, 277: 1161-1167, (1967). Williamson, et al., "Urokinase in the Treatment of Vitreous Haemorrhage", LANCET, 2:488 (1972). 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Oshima et al., "Cloning, Sequencing, And Expression Of cDNA For Human β-Glucuronidase," Proc. Natl. Acad. Sci. USA, Vol. 84, pp. 685-689 (1987). Bosslet et al., "Quantitative Considerations Supporting The Irrelevance Of Circulating Serum CEA For The Immunoscintigraphic Visualization Of CEA Expressing Carcinomas," Eur. J. Nucl. Med., Vol. 14, pp. 523-528 (1988). Walter et al., "Anti-Idiotypic Antibodies: Powerful Tools In Diagnosis And Therapy," Behring Inst. Mitt., Vol. 82, pp. 182-192 (1988). Seemann, G., et al., "Antibody Enzyme Fusion Protein For Antibody Directed Enzyme Prodrug Therapy--Carcinoembryonic Antigen-Specific Monoclonal Antibody And β-Glucuronidase Fusion Protein," Biotechnology Abstracts, Abstract No. 92-14076 (1991). Daniels et al., "Purification and Characterization of a Cytosolic Broad Specificity β-Glucosidase from Human Liver," J. of Biol. Chem., Vol. 256, 1981, pp. 13004-13013. Clark, William R., "The Experimental Foundation of Modern Immunology", pp. 458-462. 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