초록 ▼

Systems and method for sealing vascular penetrations rely on placement of a temporary barrier on the posterior side of the penetration. Penetrations are then sealed by delivering a hemostatic gel to a region over the penetration, where the barrier both inhibits loss of the gel and promotes back flow

Systems and method for sealing vascular penetrations rely on placement of a temporary barrier on the posterior side of the penetration. Penetrations are then sealed by delivering a hemostatic gel to a region over the penetration, where the barrier both inhibits loss of the gel and promotes back flow of blood into the gel. A combination of natural clotting factors in the blood and hemostatic agents in the gel promote rapid and effective sealing of the vascular penetration. Specific systems for performing the method include a barrier carrier for temporary placement of the barrier within the blood vessel and a gel delivery tube which may be positioned within a tissue tract or line of penetration simultaneously with the barrier carrier to deliver the hemostatic gel.

대표청구항 ▼

Systems and method for sealing vascular penetrations rely on placement of a temporary barrier on the posterior side of the penetration. Penetrations are then sealed by delivering a hemostatic gel to a region over the penetration, where the barrier both inhibits loss of the gel and promotes back flow

Systems and method for sealing vascular penetrations rely on placement of a temporary barrier on the posterior side of the penetration. Penetrations are then sealed by delivering a hemostatic gel to a region over the penetration, where the barrier both inhibits loss of the gel and promotes back flow of blood into the gel. A combination of natural clotting factors in the blood and hemostatic agents in the gel promote rapid and effective sealing of the vascular penetration. Specific systems for performing the method include a barrier carrier for temporary placement of the barrier within the blood vessel and a gel delivery tube which may be positioned within a tissue tract or line of penetration simultaneously with the barrier carrier to deliver the hemostatic gel. olyimide. 14. The balloon catheter according to claim 12, wherein said catheter shaft comprises a plurality of tubular members each having at least one lumen, rigidities of the proximal part and distal part of said catheter shaft mutually differ, said proximal part is formed from a metal material, and said distal part is formed from a polymer material. 15. The balloon catheter according to claim 12, 13, or 14, wherein a hydrophilic coating is applied to the distal end of said catheter shaft, and the area to be coated with said hydrophilic coating is established to extend to the proximal part of said catheter shaft that contacts said distal part. 16. The balloon Catheter according to claim 12, 13, or 14, wherein a hydrophilic coating is applied to distal end of said catheter shaft, and scope of said hydrophilic coating is established to extend to proximal part of said catheter shaft configured with a larger diameter than said distal part. 17. The balloon catheter according to any one of claims 12 to 14, wherein flexibility of said catheter shaft is made to vary, either in multiple stages or continuously, from the distal part to the proximal part thereof. 18. The balloon catheter according to any one of claims 12 to 14 wherein outer diameter of said catheter shaft is made to vary, either in multiple stages or continuously, from the distal part to the proximal part thereof. 19. The balloon catheter according to claim 1, having a guide wire lumen through which a guide wire is passed and which is formed with a limitation from the distal end of said balloon to midway along the length of said catheter shaft, wherein a hydrophilic coating is applied to the outer surface of said catheter shaft from the leading end of said balloon catheter to a location on the proximal side of the back end opening in said guide wire lumen. 20. The balloon catheter according to claim 19, wherein said hydrophilic coating is applied in a range extending from the most distal end of said balloon catheter towards the proximal side for more than 300 mm. 21. The balloon catheter according to claim 1, wherein a hydrophilic coating is applied to said balloon and catheter shaft in the distal part of said balloon catheter, and the thickness of the hydrophilic coating layer on said catheter shaft is adjusted to be greater than the thickness of the hydrophilic coating layer on said balloon and in vicinity of said balloon. 22. The balloon catheter according to claim 1, wherein a hydrophilic coating is applied at least to the catheter shaft at the distal part of said balloon catheter, and the friction resistance when hydrophilic coating layer on said catheter shaft is wetted is adjusted to be smaller than friction resistance of the balloon and at the vicinity of said balloon. 23. The balloon catheter according to claim 22, wherein said hydrophilic coating is applied only to said catheter shaft at the distal part of said balloon catheter. 24. The balloon catheter according to claim 21 or 22, wherein the thickness of said hydrophilic coating layer on said catheter shaft is 2 μm or greater. 25. The balloon catheter according to claim 1, wherein a metal tubular member is used for at least one of a plurality of tubular members constituting said catheter shaft, and the bending angle produced in said metal tubular member when released after said metal tubular member was held for 1 minute in a condition where the metal tubular member was bent 90 degrees with a radius of curvature 50 times the outer diameter thereof is 15 degrees or less. 26. The balloon catheter according to claim 1, wherein a metal tubular member is used for at least one of a plurality of tubular members constituting said catheter shaft, and the bending angle produced in said metal tubular member when released after said metal tubular member was held for 1 minute in a condition where the metal tubular member was bent 90 degrees with a radius of curvature 35 times the outer diameter thereof is 30 degrees or l