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Foamable microspheres with a foaming agent enclosed in the shell of a polymer, wherein the average particle diameter of the microspheres is within a range of 3 to 100 μm, and the coefficient of variation of the particle diameter distribution thereof is at most 1.50%, and production process of foamab

Foamable microspheres with a foaming agent enclosed in the shell of a polymer, wherein the average particle diameter of the microspheres is within a range of 3 to 100 μm, and the coefficient of variation of the particle diameter distribution thereof is at most 1.50%, and production process of foamable microspheres by a suspension polymerization process.

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Foamable microspheres with a foaming agent enclosed in the shell of a polymer, wherein the average particle diameter of the microspheres is within a range of 3 to 100 μm, and the coefficient of variation of the particle diameter distribution thereof is at most 1.50%, and production process of foamab

Foamable microspheres with a foaming agent enclosed in the shell of a polymer, wherein the average particle diameter of the microspheres is within a range of 3 to 100 μm, and the coefficient of variation of the particle diameter distribution thereof is at most 1.50%, and production process of foamable microspheres by a suspension polymerization process. 14-membered aromatic heterocyclic group containing 1 to 4 hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms in addition to carbon atoms, which group may be substituted by 1 to 5 substituents selected from the group consisting of halogen atoms, C1-3alkylenedioxy, nitro, cyano, optionally halogenated C1-6alkyl, optionally halogenated C3-6cycloalkyl, optionally halogenated C1-6alkoxy, optionally halogenated C1-6alkylthio, hydroxy, amino, mono-C1-6alkylamino, di-C1-6alkylamino, 5- to 7-membered saturated cyclic amino, formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10aryloxy-carbonyl, C7-16aralkyloxy-carbonyl, 5- or 6-membered heterocycle carbonyl, mono-C1-6alkyl-carbamoyl, di-C1-6alkyl-carbamoyl, C6-10aryl-carbamoyl, 5- or 6-membered heterocycle carbamoyl, C1-6alkylsulfonyl, C6-10arylsulfonyl, formylamino, C1-6alkyl-carboxamido, C6-10aryl-carboxamido, C1-6alkoxy-carboxamido, C1-6alkylsulfonylamino, C1-6alkyl-carbonyloxy, C6-10aryl-carbonyloxy, C1-6alkoxy-carbonyloxy, mono-C1-6alkyl-carbamoyloxy, di-C1-6alkyl-carbamoyloxy, C6-10aryl-carbamoyloxy, nicotinoyloxy and C6-10aryloxy; R8is (a) a hydrogen atom, (b) a C1-6alkyl, C2-6alkenyl, C2-6alkynyl, C3-6cycloalkyl being optionally condensed with one benzene ring, C6-14aryl or C7-19aralkyl group which may be substituted by 1 to 5 substituents selected from the group consisting of (1) halogen atoms, (2) C1-3alkylenedioxy, (3) nitro, (4) cyano, (5) optionally halogenated C1-6alkyl, (6) optionally halogenated C3-6cycloalkyl, (7) optionally halogenated C1-6alkoxy, (8) optionally halogenated C1-6alkylthio, (9) hydroxy, (10) amino, (11) mono-C1-6alkylamino, (12) di-C1-6alkylamino, (13) formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10aryloxy-carbonyl, C7-16aralkyloxy-carbonyl, 5- or 6-membered heterocycle carbonyl, mono-C1-6alkyl-carbamoyl, di-C1-6alkyl-carbamoyl, C6-10aryl-carbamoyl, 5- or 6-membered heterocycle carbamoyl, C1-6alkylsulfonyl or C6-10arylsulfonyl, (14) formylamino, C1-6alkyl-carboxamido, C6-10aryl-carboxamido, C1-6alkoxy-carboxamido or C1-6alkylsulfonylamino, (15) C1-6alkyl-carbonyloxy, C6-10aryl-carbonyloxy, C1-6alkoxy-carbonyloxy, mono-C1-6alkyl-carbamoyloxy, di-C1-6alkyl-carbamoyloxy, C6-10aryl-carbamoyloxy or nicotinoyloxy, (16) 5- to 7-membered saturated cyclic amino, (17) sulfo, (18) a phenyl or 5- or 6-membered aromatic heterocyclic group containing 1 to 4 hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms in addition to carbon atoms, each of which may be substituted by 1 to 5 substituents selected from the group consisting of halogen atoms, C1-3alkylenedioxy, nitro, cyano, optionally halogenated C1-6alkyl, optionally halogenated C3-6cycloalkyl, optionally halogenated C1-6alkoxy, optionally halogenated C1-6alkylthio, hydroxy, amino, mono-C1-6alkylamino, di-C1-6alkylamino, 5- to 7-membered saturated cyclic amino, formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10aryloxy-carbonyl, C7-16aralkyloxy-carbonyl, 5- or 6-membered heterocycle carbonyl, mono-C1-6alkyl- carbamoyl, di-C1-6alkyl-carbamoyl, C6-10aryl-carbamoyl, 5- or 6-membered heterocycle carbamoyl, C1-6alkylsulfonyl, C6-10arylsulfonyl, formylamino, C1-6alkyl-carboxamido, C6-10aryl-carboxamido, C1-6alkoxy-carboxamido, C1-6alkylsulfonylamino, C1-6alkyl-carbonyloxy, C6-10aryl-carbonyloxy, C1-6alkoxy-carbonyloxy, mono-C1-6alkyl-carbamoyloxy, di-C1-6alkyl-carbamoyloxy, C6-10aryl-carbamoyloxy, nicotinoyloxy and C6-10aryloxy, (19) an aromatic ring assembly group which is composed of two or three rings selected from the group consisting of a C6-14aromatic hydrocarbon, a C6-14quinone and a 5- to 14-membered aromatic heterocyclic ring containing 1 to 4 hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen atoms in addition to carbon atoms, are directly bonded to each other via a single bond, and which group may be substituted by 1 to 5 substituents selected from the group consisting of halogen atoms, C1-3alkylenedioxy, nitro, cyano, optionally halogenated C1-6alkyl, optionally halogenated C3-6cycloalkyl, optionally halogenated C1-6alkoxy, optionally halogenated C1-6alkylthio, hydroxy, amino, mono-C1-6alkylamino, di-C1-6alkylamino, 5- to 7-membered saturated cyclic amino, formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10aryloxy-carbonyl, C7-16aralkyloxy-carbonyl, 5- or 6-membered heterocycle carbonyl, mono-C1-6alkyl-carbamoyl, di-C1-6alkyl-carbamoyl, C6-10aryl-carbamoyl, 5- or 6-membered heterocycle carbamoyl, C1-6alkylsulfonyl, C6-10arylsulfonyl, formylamino, C1-6alkyl-carboxamido, C6-10aryl-carboxamido, C1-6alkoxy-carboxamido, C1-6alkylsulfonylamino, C1-6alkyl-carbonyloxy, C6-10aryl-carbonyloxy, C1-6alkoxy-carbonyloxy, mono-C1-6alkyl-carbamoyloxy, di-C1-6alkyl-carbamoyloxy, C6-10aryl-carbamoyloxy, nicotinoyloxy and C6-10aryloxy, and (20) a fused bi- or tn-cyclic C10-14aryl or 9- to 14-membered aromatic heterocyclic group containing 1 to 4 hetero atoms selected from the group consisting of nitrogen, oxygen and sulfur atoms in addition to carbon atoms, which group may be substituted by 1 to 5 substituents selected from the group consisting of halogen atoms, C1-3alkylenedioxy, nitro, cyano, optionally halogenated C1-6alkyl, optionally halogenated C3-6cycloalkyl, optionally halogenated C1-6alkoxy, optionally halogenated C1-6alkylthio, hydroxy, amino, mono-C1-6alkylamino, di-C1-6alkylamino, 5- to 7-membered saturated cyclic amino, formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10aryloxy-carbonyl, C7-16aralkyloxy-carbonyl, 5- or 6-membered heterocycle carbonyl, mono-C1-6alkyl-carbamoyl, di-C1-6alkyl-carbamoyl, C6-10aryl-carbamoyl, 5- or 6-membered heterocycle carbamoyl, C1-6alkylsulfonyl, C6-10arylsulfonyl, formylamino, C1-6alkyl-carboxamido, C6-10aryl-carboxamido, C1-6alkoxy-carboxamido, C1-6alkylsulfonylamino, C1-6alkyl-carbonyloxy, C6-10aryl-carbonyloxy, C1-6alkoxy-carbonyloxy, mono-C1-6alkyl-carbamoyloxy, di-C1-6alkyl-carbamoyloxy, C6-10aryl-carbamoyloxy, nicotinoyloxy and C6-10aryloxy, or (c) formyl, carboxy, carbamoyl, C1-6alkyl-carbonyl, C1-6alkoxy-carbonyl, C6-10aryl-carbonyl, C6-10