초록 ▼

The present invention encompasses methods of treating patients for essential hypertension. The invention also includes related pharmaceutical compositions of nitroxides. Specific drugs, such as 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol) are disclosed. These compositions are also contemp

The present invention encompasses methods of treating patients for essential hypertension. The invention also includes related pharmaceutical compositions of nitroxides. Specific drugs, such as 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol) are disclosed. These compositions are also contemplated for use in the treatment of oxidative stress and modulation of blood pressure.

대표청구항 ▼

The present invention encompasses methods of treating patients for essential hypertension. The invention also includes related pharmaceutical compositions of nitroxides. Specific drugs, such as 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol) are disclosed. These compositions are also contemp

The present invention encompasses methods of treating patients for essential hypertension. The invention also includes related pharmaceutical compositions of nitroxides. Specific drugs, such as 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol) are disclosed. These compositions are also contemplated for use in the treatment of oxidative stress and modulation of blood pressure. each finger section having a tip length less than the actual length of the finger of the hand, the finger sections defining a hand width; an open base at the distal end, the open base having a width that is larger than the hand width; at least one tie affixed to the mit at the distal end and adjacent to the base, the tie having a tie length. 7. The item of wearing apparel of claim 6 wherein the mit is made of a pliable material. 8. The item of wearing apparel of claim 6 wherein the inward flare angle is between 10 degrees and 35 degrees. 9. The item of wearing apparel of claim 6 wherein the outward flare angle is between 10 degrees and 35 degrees. 10. The item of wearing apparel of claim 6 wherein the mit has two ties which are located at the distal end and adjacent to the base on opposite sides of the mit. 11. A method for using an item of wearing apparel to retrieve and dispose of waste debris, comprising the steps of: providing a self-contained mit having a hand portion and a heel portion, and further defining an exterior side and an interior side, the hand portion and the heel portion being formed along a flared portion; the hand portion having a hand width and further defining a plurality of finger sections disposed at one end of the hand portion, the plurality of finger sections each having a finger length for receiving a tip of a corresponding finger of a hand, the finger length of each finger section having a tip length less than the actual length of the finger of the hand; the heel portion having a heel width and further defining an open base disposed at one end of the heel portion located opposite the finger sections of the hand portion, the heel width being larger than the hand width; the flared portion tapering inwardly at an inward flare angle from the hand portion to the heel portion and tapering outwardly at an outward flare angle from the heel portion to the base; the inward flare angle being substantially equal to the outward flare angle on one side of the mit and the inward flare angle being substantially equal to twice the outward flare angle on the other side of the mit: and at least one tie being affixed to the base of the heel portion; inserting a hand into the open base of the of the mit, the hand being received through the heel portion and into the hand portion such that the tips of the fingers of the hand are individually received by the corresponding finger sections; retrieving the waste debris within the hand portion on the exterior side of the mit; reversing the mit into a bag such that the exterior side of the mit holding the waste debris becoming a new interior side of the bag to hold the waste debris and the interior side of the mit becoming a new exterior side of the bag; removing the hand from the bag; securing the bag using the at least one tie; and disposing of the bag containing the waste debris. 12. A method for using an item of wearing apparel to retrieve and dispose of waste debris, comprising the steps of: providing a mit having a proximal end and a distal end separated by a mit length and further defining a flared portion extending from the proximal end of the mit to the distal end, the flared portion tapering inwardly at an inward flare angle from the proximal end to a convex point and tapering outwardly at an outward flare angle from the convex point to the distal end; the inward flare angle being substantially equal to the outward flare angle on one side of the mit and the inward flare angle being substantially equal to twice the outward flare angle on the other side of the mit; a plurality of finger sections at the proximal end, the plurality of finger sections each having a finger length for receiving a tip of a corresponding finger of a hand, the finger length of each finger section having a tip length less than the actual length of the finger of the hand, the finger sections defining a hand width; an open base at the distal end, the open base having a width that