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A transdermal administrating device is provided which includes an active electrode having a conductive electrode layer and a conductive drug layer applied on the bottom surface of the conductive electrode layer. The bottom surface of the conductive drug layer is capable of being placed in contact wi

A transdermal administrating device is provided which includes an active electrode having a conductive electrode layer and a conductive drug layer applied on the bottom surface of the conductive electrode layer. The bottom surface of the conductive drug layer is capable of being placed in contact with skin. The device also includes an inert electrode capable of being placed in contact with skin and spaced from the active electrode, a set of conductive electrode layers each having a different standard single electrode potential, and a controller for measuring an internal resistance of the skin tissue under the region between the conductive electrode layers and for controlling an electric current passing between the active electrode and the inert electrode based on the variation in the internal resistance. In addition, a dermocontact mechanism is provided for keeping the active electrode, the inert electrode, and the set of conductive electrode layers in contact with skin.

대표청구항 ▼

A transdermal administrating device is provided which includes an active electrode having a conductive electrode layer and a conductive drug layer applied on the bottom surface of the conductive electrode layer. The bottom surface of the conductive drug layer is capable of being placed in contact wi

A transdermal administrating device is provided which includes an active electrode having a conductive electrode layer and a conductive drug layer applied on the bottom surface of the conductive electrode layer. The bottom surface of the conductive drug layer is capable of being placed in contact with skin. The device also includes an inert electrode capable of being placed in contact with skin and spaced from the active electrode, a set of conductive electrode layers each having a different standard single electrode potential, and a controller for measuring an internal resistance of the skin tissue under the region between the conductive electrode layers and for controlling an electric current passing between the active electrode and the inert electrode based on the variation in the internal resistance. In addition, a dermocontact mechanism is provided for keeping the active electrode, the inert electrode, and the set of conductive electrode layers in contact with skin. bata, 257/777 , and the second exciting electrode is formed on the second principal plane. 4. The piezoelectric element according to claim 3, wherein the first and second principal planes are X planes of the piezoelectric substrate, and the side wall in the longitudinal direction is parallel to a plane obtained by rotating an XY plane of the piezoelectric substrate for 56° to 58° clockwise about an X-axis. 5. The piezoelectric element according to claim 4, wherein the direction of the normal line is a direction obtained by rotating Y-axis of the piezoelectric substrate for 47° to 56° clockwise on a YZ plane. 6. The piezoelectric element according to claim 5, wherein the width W and the thickness H of the piezoelectric substrate satisfy the relationship 2.9≤W/H≤3.1 or 3.7≤W/H≤3.9. 7. The piezoelectric element according to claim 6, wherein the piezoelectric substrate includes first and second piezoelectric substrates, and the first piezoelectric substrate and the second piezoelectric substrate are stacked in such a manner that their polarization directions are opposite to each other. 8. The piezoelectric element according to claim 6, wherein the side wall in the longitudinal direction is a plane cleaved by laser irradiation. 9. The piezoelectric element according to claim 2, wherein the piezoelectric substrate is formed of LiTaO3single crystal, the pair of electrodes includes an input electrode and an output electrode, the input electrode and the output electrode are formed on the first principal plane of the piezoelectric substrate, the piezoelectric element further comprises a ground electrode formed on the second principal plane, the side wall is a side wall in a longitudinal direction of the piezoelectric substrate, and a normal line of an edge of the input electrode and a normal line of an edge of the output electrode are parallel to each other and are nonparallel to the side wall in the longitudinal direction. 10. The piezoelectric element according to claim 9, wherein the first and second principal planes are X planes of the piezoelectric substrate, and the side wall of the piezoelectric substrate is parallel to a plane obtained by rotating an XY plane of the piezoelectric substrate for 56° to 58° clockwise about an X-axis. 11. The piezoelectric element according to claim 10, wherein the direction of the normal line is a direction obtained by rotating a Y-axis of the piezoelectric substrate for 47° to 56° clockwise on a YZ plane. 12. The piezoelectric element according to claim 11, wherein the width W and the thickness H of the piezoelectric substrate satisfy the relationship 2.9≤W/H≤3.1 or 3.7≤W/H≤3.9. 13. The piezoelectric element according to claim 12, wherein the piezoelectric substrate includes a first piezoelectric substrate and a second piezoelectric substrate, and the first piezoelectric substrate and the second piezoelectric substrate are stacked in such a manner that their polarization directions are opposite to each other. 14. The piezoelectric element according to claim 12, wherein the side wall in the longitudinal direction is a plane cleaved by laser irradiation. 15. A mobile communication device comprising the piezoelectric element according to claim 1.