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A method and apparatus for treating patients with neuropsychiatric disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable neurostimulator with a

A method and apparatus for treating patients with neuropsychiatric disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable neurostimulator with at least one operatively coupled nerve electrode to apply the pulse signal to the selected nerve branch at a location in the vicinity of the patient's diaphragm, either slightly above or slightly below the diaphragm. The implantable neurostimulator is programmable to enable physician programming of electrical and timing parameters of the pulse signal, to generate the desired therapy regimen for alleviating the disorder. Patient activation of the device is permitted in the case of treating a neuropsychiatric disorder such as depression, where the patient is able to sense a symptom of a disorder.

대표청구항 ▼

A method and apparatus for treating patients with neuropsychiatric disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable neurostimulator with a

A method and apparatus for treating patients with neuropsychiatric disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable neurostimulator with at least one operatively coupled nerve electrode to apply the pulse signal to the selected nerve branch at a location in the vicinity of the patient's diaphragm, either slightly above or slightly below the diaphragm. The implantable neurostimulator is programmable to enable physician programming of electrical and timing parameters of the pulse signal, to generate the desired therapy regimen for alleviating the disorder. Patient activation of the device is permitted in the case of treating a neuropsychiatric disorder such as depression, where the patient is able to sense a symptom of a disorder. unable Filter and Laser based on Two-mode Fiber", Optics Letters, Jan. 1996, vol. 21, No. 1, pp. 27-29. Yun, S.H. et al, "Suppression of Polarization Dependence in a Two-Mode Fiber Acousto-Optic Device", Optics Letters, Jun. 15, 1996, vol. 21, No. 12, pp. 908-910. Kim, H.S. et al, "Longitudinal Mode Control in Few-Mode Erbium-Doped Fiber Lasers", Optics Letters, Aug. 1, 1996, vol. 21, No. 15, pp. 1144-1146. Jeon, M.Y. et al, "An Electronically Wavelength-Tunable Mode-Locked Fiber Laser Using an All-Fiber Acoustooptic Tunable Filter", IEEE Photonics Technology Letters, Dec. 1996, vol. 8, No. 12, pp. 1618-1620. Kim, H.S. et al, "All-fiber acousto-optic tunable notch filter with electronically controllable spectral profile", Optics Letters, Oct. 1, 1997, vol. 22, No. 19, pp. 1476-1478. Yun, S.H. et al, "Wavelength-Swept Fiber Laser with Frequency Shifted Feedback and Reasonantly Swept Intra-Cavity Acoustooptic Tunable Filter", IEEE Journal of Selected Topics in Quantum Electronics, Aug. 1997, vol. 3, No. 4, pp. 1087-1096 (Invited Paper). Jeon, M.Y. et al, "Harmonically mode-locked fiber laser with an acoutso-optic modulator in a Sagnac loop and Faraday rotating mirror cavity", Optics Communications, Apr. 15, 1998, vol. 149, pp. 312-316. Kim, H.S. et al, "Actively gain-flattened erbium-do