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Apparatus and methods for capture and analysis of particulate entities 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/553
출원번호 US-0381795 (1999-09-23)
국제출원번호 PCT/US98/05911 (1998-03-24)
국제공개번호 WO98/43067 (1998-10-01)
발명자 / 주소
  • Terstappen, Leon W. M. M.
  • Rao, Galla C.
출원인 / 주소
  • Immunivest Corporation
대리인 / 주소
    Dann Dorfman Herrell and Skillman
인용정보 피인용 횟수 : 64  인용 특허 : 27

초록

Apparatus and methods are disclosed which facilitate immobilization of magnetically labelled particulate entities, e.g., cells, preferably in a defined pattern, on a collection surface via binding between specific binding pair members, as an aid to particle analysis.

대표청구항

Apparatus and methods are disclosed which facilitate immobilization of magnetically labelled particulate entities, e.g., cells, preferably in a defined pattern, on a collection surface via binding between specific binding pair members, as an aid to particle analysis. is principally gamma manganese o

이 특허에 인용된 특허 (27)

  1. Terstappen Leon W. M. M. (Huntingdon Valley PA) Rao Galla C. (Princeton NJ) Gohel Dhanesh I. (Levittown PA) Feeley Brian P. (Easton PA) Gross Steven (Ambler PA) Church Ellen S. (Trenton NJ) Liberti P, Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population th.
  2. Liberti Paul A. (Churchville) Feeley Brian P. (Easton) Gohel Dhanesh I. (Philadelphia PA), Apparatus and methods for magnetic separation.
  3. Liberti Paul A. (Churchville PA) Wang Yuzhou (Wayne PA) Tang Weixin (Devon PA) Feeley Brian P. (Easton PA) Gohel Dhanesh I. (Philadelphia PA), Apparatus and methods for magnetic separation featuring external magnetic means.
  4. Liberti Paul A. (Churchville PA) Feeley Brian P. (Easton PA) Gohel Dhanesh I. (Philadelphia PA), Apparatus for magnetic separation featuring external magnetic means.
  5. Liberti Paul A., Detection of bound analyte by magnetic partitioning and masking.
  6. Babon Jeff,AUX ; Youil Rima,AUX ; Stoerker Jay ; Huff Anne ; Cotton Richard G. H.,AUX, Detection of mismatches by resolvase cleavage using a magnetic bead support.
  7. Lansdorp Peter (Vancouver CAX) Thomas Terry (Vancouver CAX), Device for separating magnetically labelled cells.
  8. Jou Yi-Her (Libertyville IL) Stroupe Stephen D. (Libertyville IL) Markese James J. (Libertyville IL), Devices for performing ion-capture binding assays.
  9. Ugelstad John,NOX ; Stenstad Per,NOX ; Kilaas Lars,NOX ; Berge Arvid,NOX, Immobilization and separation of cells and other particles.
  10. Uzan Michel,FRX ; Gicquel Thierry,FRX ; Lentwojt Edouard,FRX ; Marminio Dario,FRX, Immunodiagnostic reagent for carrying out a multi-stage immunoassay of at least one biological substance in a plurality.
  11. Kausch Albert P. (Stonington CT) Narayanswami Sandya (Irvine CA) Manning Jerry E. (San Clemente CA) Hamkalo Barbara A. (Laguna Beach CA), Isolation of biological materials using magnetic particles.
  12. Matte Claude (Paris FRX) Muller Anne (Gif/Yvette FRX), Magnetic device for immunological analysis of a solid phase.
  13. Liberti Paul A. ; Wang Yuzhou, Magnetic immobilization and manipulation of biological entities.
  14. Wang Yuzhou ; Tang Weixin ; Liberti Paul A., Magnetic separation apparatus.
  15. Miltenyi Stefan (Bergisch Gladbach DEX) Dority Douglas Bryan (Mill Valley CA) Phi-Wilson Janette (Los Altos Hills CA), Magnetic separation apparatus and method.
  16. Liberti Paul A. (Churchville PA) Gohel Dhanesh I. (Philadelphia PA), Manipulation of colloids for facilitating magnetic separations.
  17. Colin Bruno,FRX ; Theretz Alain,FRX, Method and device for the determination of an analyte using super paramagnetic reactive particles.
  18. Wang Yuzhou (Wayne PA) Tang Weixin (Landsdale PA) Cronin William J. (Matawan NJ) Liberti Paul A. (Huntingdon Valley PA), Method for magnetic separation featuring magnetic particles in a multi-phase system.
  19. Senyei Andrew E. (Chicago IL) Widder Kenneth J. (Chicago IL), Method of magnetic separation of cells and the like, and microspheres for use therein.
  20. Rossomando Edward F. (West Hartford CT) Hadjimichael Jane (Simsbury CT), Method of using magnetic particles for isolating, collecting and assaying diagnostic ligates.
  21. Liberti Paul A. (Huntingdon Valley PA) Wang Yozhou (Media PA), Methods and devices for manipulation of magnetically collected material.
  22. Leland John K. ; Shah Haresh P. ; Kenten John H. ; Goodman Jack E. ; Lowke George E. ; Namba Yuzaburo,JPX ; Blackburn Gary F. ; Massey Richard J., Methods for improved particle electrochemiluminescence assays.
  23. Liberti Paul A. ; Wang Yuzhou, Methods for magnetic immobilization and manipulation of cells.
  24. Liberti Paul A. (Huntingdon Valley PA) Rao Galla C. (Princeton NJ) Chiarappa Joseph N. (Flemington NJ), Methods for the manufacture of magnetically responsive particles.
  25. Terstappen Leon W. M. M. ; Liberti Paul A., Quantitative cell analysis methods employing magnetic separation.
  26. Civin Curt I. (Baltimore MD), Release of cells from affinity matrices.
  27. Rao Galla Chandra (Princeton NJ) Liberti Paul A. (Huntingdon Valley PA), Surface immobilization of magnetically collected materials.

이 특허를 인용한 특허 (64)

  1. Wang, Shan X.; Osterfeld, Sebastian J.; Yu, Heng; Pourmand, Nader; White, Robert L., Analyte detection with magnetic sensors.
  2. Dryga, Sergey A.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Esch, Victor C., Analyzing bacteria without culturing.
  3. Dryga, Sergey A.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Esch, Victor C., Analyzing bacteria without culturing.
  4. Browne, Douglas; Straus, Don; Mace, Chad, Cassette containing growth medium.
  5. Aviles, Robert C.; Michaud, Devin T.; Browne, Douglas J., Cassette for sterility testing.
  6. Zaugg, Frank; Tobias, Renee; McManus-Munoz, Silvia; Kernen, Peter; Ruiz-Taylor, Laurence; Wagner, Peter, Cell assay kit and method.
  7. Zaugg, Frank; Tobias, Renee; McManus-Munoz, Silvia; Kernen, Peter; Ruiz-Taylor, Laurence; Wagner, Peter, Cell assay kit and method.
  8. Zaugg, Frank; Tobias, Renee; McManus-Munoz, Silvia; Kernen, Peter; Ruiz-Taylor, Laurence; Wagner, Peter, Cell assay kit and method.
  9. Handique, Kalyan; Gogoi, Priyadarshini; Siemer, Christopher; Javdani, Saedeh Sepehri, Cell capture system and method of use.
  10. Handique, Kalyan; Gogoi, Priyadarshini; Siemer, Christopher; Javdani, Saedeh Sepehri, Cell capture system and method of use.
  11. Handique, Kalyan; Gogoi, Priyadarshini; Siemer, Christopher; Javdani, Saedeh Sepehri, Cell capture system and method of use.
  12. Fernando, Rohan M.; Ryan, Wayne L.; Hunsley, Brad, Compositions and methods for stabilizing circulating tumor cells.
  13. Dryga, Sergey A.; Esch, Victor C.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Ung, Thearith H.; Sitdikov, Ravil A., Compositions for isolating a target analyte from a heterogeneous sample.
  14. Fernando, M. Rohan, Devices and compositions for preservation of cell-free nucleic acids.
  15. Esch, Victor C.; Dryga, Sergey A.; Clarizia, Lisa-Jo Ann, Extracting low concentrations of bacteria from a sample.
  16. Humphries, David E; Pollard, Martin J; Elkin, Christopher J, High performance hybrid magnetic structure for biotechnology applications.
  17. Humphries,David E.; Pollard,Martin J.; Elkin,Christopher J., High performance hybrid magnetic structure for biotechnology applications.
  18. Ryan, Wayne L.; Grunkemeyer, James A, Inactivated virus compositions and methods of preparing such compositions.
  19. Yellen, Benjamin B.; Friedman, Gennady, Magnetic fluid manipulators and methods for their use.
  20. Yellen, Benjamin B.; Friedman, Gennady, Magnetic fluid manipulators and methods for their use.
  21. Yellen, Benjamin B.; Friedman, Gennady, Magnetic fluid manipulators and methods for their use.
  22. Wang, Shan X.; White, Robert L.; Webb, Chris D.; Li, Guanxiong, Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules.
  23. Wang, Shan X.; White, Robert L.; Webb, Chris D.; Li, Guanxiong, Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules.
  24. Garcia Gros, Luis Miguel; Talmer, Mark; Schroeder, Gerhardt P.; Dahlstrom, Paul C.; Serra Domènech, Jose, Magnetic particle washing station.
  25. Abrams, Ezra; Gite, Sadanand; Shinefeld, Lisa; Straus, Don; Siek, Gordon; Yantz, Greg, Method for detecting analytes.
  26. Bukshpan,Shmuel; Zilberstein,Gleb, Method for sorting and separating living cells.
  27. Dryga, Sergey A., Methods for degrading nucleic acid.
  28. Dryga, Sergey A.; Esch, Victor C.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Ung, Thearith H.; Sitdikov, Ravil A., Methods for isolating a target analyte from a heterogeneous sample.
  29. Dryga, Sergey A.; Esch, Victor C.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Ung, Thearith H.; Sitdikov, Ravil A., Methods for isolating a target analyte from a heterogeneous sample.
  30. Dryga, Sergey A.; Esch, Victor C.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Ung, Thearith H.; Sitdikov, Ravil A., Methods for isolating a target analyte from a heterogeneous sample.
  31. Dryga, Sergey A.; Esch, Victor C.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Ung, Thearith H.; Sitdikov, Ravil A., Methods for isolating a target analyte from a heterogenous sample.
  32. Fernando, M. Rohan, Methods for preservation of cell-free nucleic acids.
  33. Dykes, Colin; Dryga, Sergey A.; Clarizia, Lisa-Jo Ann; Adams, Eddie W.; Norvell, Meghan, Methods for raising antibodies.
  34. Dykes, Colin, Methods for universal target capture.
  35. Achrol, Achal Singh; Sethu, Palaniappan, Microfluidic method and system for isolating particles from biological fluid.
  36. Adolphi, Natalie Louise; McDowell, Andrew Frederick, NMR, instrumentation, and flow meter/controller continuously detecting MR signals, from continuously flowing sample material.
  37. Fernando, M. Rohan, Preservation of cell-free RNA in blood samples.
  38. Fernando, M. Rohan, Preservation of cell-free RNA in blood samples.
  39. Fernando, M. Rohan, Preservation of cell-free RNA in blood samples.
  40. Fernando, M. Rohan, Preservation of cell-free nucleic acids.
  41. Straus, Don, Rapid and sensitive detection of cells and viruses.
  42. Straus, Don, Rapid and sensitive detection of molecules.
  43. Straus, Don, Rapid detection of replicating cells.
  44. Straus, Don, Rapid detection of replicating cells.
  45. Smith, Michael John, Sample card holder.
  46. Macemon, James H., Sample entry.
  47. Dryga, Sergey A.; Esch, Victor C.; Saul, Richard G.; McDowell, Andrew F., Separating target analytes using alternating magnetic fields.
  48. Pagano, Paul; Zhang, Yanting; Qian, Jiangrong Karen; Soh, Hyongsok Tom; Dempsey, Paul W.; De Fusco, Andre′ , Sheath flow devices and methods.
  49. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Siemer, Christopher; Zhou, Yi, System and method for capturing and analyzing cells.
  50. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Siemer, Christopher; Zhou, Yi, System and method for capturing and analyzing cells.
  51. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Siemer, Christopher; Zhou, Yi, System and method for capturing and analyzing cells.
  52. Handique, Kalyan; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Zhou, Yi, System and method for capturing and analyzing cells.
  53. Handique, Kalyan; Gogoi, Priyadarshini; Zhou, Yi; Javdani, Saedeh Sepehri, System and method for capturing and analyzing cells.
  54. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Siemer, Christopher; Zhou, Yi, System for capturing and analyzing cells.
  55. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Siemer, Christopher; Zhou, Yi; Sepehri, Saedeh Javdani, System for capturing and analyzing cells.
  56. Handique, Kalyan; Gleason, Kyle; Payne, Austin; Gogoi, Priyadarshini; Siemer, Christopher; Zhou, Yi; Sepehri, Saedeh Javdani, System for capturing and analyzing cells.
  57. Handique, Kalyan; Gleason, Kyle; Siemer, Christopher; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Parunak, Gene; Kehrer, Aaron; Meines, Jon, System for imaging captured cells.
  58. Handique, Kalyan; Gleason, Kyle; Siemer, Christopher; Gogoi, Priyadarshini; Javdani, Saedeh Sepehri; Parunak, Gene; Kehrer, Aaron; Meines, Jon, System for imaging captured cells.
  59. Handique, Kalyan; Gogoi, Priyadarshini; Zhou, Yi; Sepehri, Saedeh; Siemer, Christopher, System for isolating cells.
  60. Osterfeld, Sebastian J.; Wang, Shan X., Systems and methods for high-throughput detection of an analyte in a sample.
  61. Osterfeld, Sebastian J.; Wang, Shan X., Systems and methods for high-throughput detection of an analyte in a sample.
  62. Osterfeld, Sebastian J.; Wang, Shan Xiang, Systems and methods for high-throughput detection of an analyte in a sample.
  63. Sitdikov, Ravil A.; Adams, Eddie W.; Torrance, Magdalena A.; Aley, David K.; Smith, Erik J.; Esch, Victor C., Target capture system.
  64. Norvell, Meghan, Target detection.
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