IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0590593
(2000-06-09)
|
발명자
/ 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
20 인용 특허 :
10 |
초록
▼
A method of setting user control preferences where a personal communication device communicates user control preferences to a control device. The control device controls the controllable attributes of a location in accordance with the user control preferences. In addition, general control preference
A method of setting user control preferences where a personal communication device communicates user control preferences to a control device. The control device controls the controllable attributes of a location in accordance with the user control preferences. In addition, general control preferences can be communicated to the control device followed by manual adjustment of the controllable attributes where the adjusted controllable attributes are communicated to the personal communication device and stored therein.
대표청구항
▼
A method of setting user control preferences where a personal communication device communicates user control preferences to a control device. The control device controls the controllable attributes of a location in accordance with the user control preferences. In addition, general control preference
A method of setting user control preferences where a personal communication device communicates user control preferences to a control device. The control device controls the controllable attributes of a location in accordance with the user control preferences. In addition, general control preferences can be communicated to the control device followed by manual adjustment of the controllable attributes where the adjusted controllable attributes are communicated to the personal communication device and stored therein. c field to said tissue of said treatment site, and wherein at least one needle electrode of said pair of needle electrodes allows for injection of an agent to said tissue of said treatment site. 7. The apparatus of claim 6, wherein one of said pair of needle electrodes is configured to receive a first charge and the other of said pair of needle electrodes is configured to receive a second charge different from said first charge. 8. The apparatus of claim 6, wherein said electric field increases the permeability of the cell membranes of cells at said treatment site. 9. The apparatus of claim 6, wherein said catheter assembly comprises at least one inflatable balloon. 10. The apparatus of claim 6, wherein said needle electrodes are located at a distal tip of said catheter assembly. 11. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein said electric field is a pulsed field of between 1 and approximately 100 pulses per second. 12. The method of claim 4, wherein said pulses are of a duration of between approximately 10 microseconds to approximately 100 milliseconds per pulse. 13. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein said electric field has a field strength of between approximately 10 V/cm and approximately 20 KV/cm. 14. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein said treatment site is an atherosclerotic lesion in a blood vessel. 15. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein the said treatment site is a restenotic lesion in a blood vessel. 16. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle ele ctrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein the cells are smooth muscle cells. 17. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein said agent is selected from a group of extracellular matrix modulators, apoptosis inducers, anti-angiogenesis agents, matrix metalloproteinases (MMPs), and reperfusion injury inhibitors and combinations thereof. 18. A method of intracellular delivery of an agent, comprising: positioning a catheter having a pair of needle electrodes thereon at a treatment site; causing said needle electrodes to penetrate in tissues of said treatment site; introducing an agent through at least one of said needle electrodes to said treatment site; and applying an electric field to said treatment site by said pair of needle electrodes to increase permeability of the cell membranes of the cells at said treatment site to allow said agent to pass through the cell membranes into the cells, wherein said agent is selected from a group of nucleic acids, peptides and polypeptides. 19. An intraluminal apparatus for introducing an agent to a treatment site, comprising: a catheter assembly for accessing a treatment site through an anatomical lumen; and a pair of needle electrodes integrated with said catheter assembly; wherein said pair of needle electrodes are capable of being in electrical communication with a generator for applying an electric field to said treatment site, and wherein at least one needle electrode of said pair of needle electrodes allows for injection of an agent to said treatment site, and wherein said electric field has a field strength of between approximately 10 V/cm and approximately 20 KV/cm. 20. An intraluminal apparatus for introducing an agent to a treatment site, comprising: a catheter assembly for accessing a treatment site through an anatomical lumen; and a pair of needle electrodes integrated with said catheter assembly; wherein said pair of needle electrodes are capable of being in electrical communication with a generator for applying an electric field to said treatment site, and wherein at least one needle electrode of said pair of needle electrodes allows for injection of an agent to said treatment site, and wherein said apparatus is used for intracellular delivery of an agent to an atherosclerotic region of a blood vessel. 21. An intraluminal apparatus for introducing an agent to a treatment site, comprising: a catheter assembly for accessing a treatment site through an anatomical lumen; and a pair of needle electrodes integrated with said catheter assembly; wherein said pair of needle electrodes are capable of being in electrical communication with a generator for applying an electric field to said treatment site, and wherein at least one needle electrode of said pair of needle electrodes allows for injection of an agent to said treatment site, and wherein said apparatus is used for intracellular delivery of an agent to a restenotic region of a blood vessel. 22. An intraluminal apparatus for introducing an agent to a treatment site, comprising: a catheter assembly for accessing a treatment site through an anatomical lumen; and a pair of needle electrodes integrated with said catheter assembly; wherein said pair of needle electrodes are capable of being in electrical communication with a generator for applying an el
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