초록 ▼

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer oating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embod

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer oating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embodiment the biologically active material is delivered through lumens in the micro-needles. Another embodiment of the invention is an apparatus for delivery of biologically active materials comprising a catheter with a balloon disposed thereon and a shockwave generator for producing a shockwave for delivering the biologically active material to a body lumen. Methods for delivery of biologically active materials are also disclosed.

대표청구항 ▼

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer oating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embod

An apparatus for delivery of biologically active materials comprises a catheter and balloon having micro-needles or pores. In the apparatus, the balloon can have a polymer oating containing the biologically active material, and the apparatus can include a sheath surrounding the balloon. In one embodiment the biologically active material is delivered through lumens in the micro-needles. Another embodiment of the invention is an apparatus for delivery of biologically active materials comprising a catheter with a balloon disposed thereon and a shockwave generator for producing a shockwave for delivering the biologically active material to a body lumen. Methods for delivery of biologically active materials are also disclosed. essure, pressurized fluid, and gas. 17. The device of claim 13, wherein said motor is an electric motor. 18. The device of claim 13, wherein said motor is of a type driven by negative pressure. 19. The device of claim 13, wherein said motor is of a type driven by fluid under pressure. 20. The device of claim 13, wherein said cannula shaft is provided at the distal end thereof with a series of scalloped edges or geometric edges. 21. The device of claim 13, additionally including a counter rotating component for canceling rotational torque of the cannula shaft. 22. The device of claim 13, additionally including means for generating concomitant ultrasonic vibration at least in the distal end of the cannula shaft. 23. The device of claim 13, additionally including a member extending through said cannula shaft and attached to an ultrasonic source for generating ultrasonic vibration through the cannula shaft. 24. The device of claim 13, additionally including a counter-rotating gearing arrangement mounted to said motor.