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Self-contained device integrating nucleic acid extraction, amplification and detection 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12P-019/34
  • C12M-001/34
  • C07H-021/04
  • G01N-030/96
  • G01N-030/02
출원번호 US-0705043 (2000-11-02)
발명자 / 주소
  • Kozwich, Diane L.
  • Gerdes, John C.
출원인 / 주소
  • Xtrana, Inc.
대리인 / 주소
    Petersen, Steven C.O'Rourke, Sarah S.Hogan & Hartson LLP
인용정보 피인용 횟수 : 32  인용 특허 : 14

초록

Self-contained devices are described that integrate nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequen

대표청구항

Self-contained devices are described that integrate nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequen

이 특허에 인용된 특허 (14)

  1. Zaun Peter (Libertyville IL) Bouma Stanley R. (Grayslake IL) Gordon Julian (Lake Bluff IL) Kotlarik John J. (Vernon Hills IL), Apparatus and method for amplifying and detecting target nucleic acids.
  2. Reinhartz Avraham (Rehovot ILX) Alajem Sarah (Kfar Hanagid ILX) Paper Thierry (Paris FRX) Herzberg Max (Satariya ILX), Apparatus and method for transport of nucleic acid sequences by capillary action on a solid support and detection of the.
  3. Rabson Arthur L. (Chester NJ) Palmieri Thomas (Paramus NJ) Olson Douglas R. (Doylestown PA), Centrifuge vessel with coaxial waste chamber having cap to prevent waste fluid transfer from the chamber into the vessel.
  4. Neri Bruce P. ; Curtis John S.,GB2 ; Collins Mark L. ; Ryan Danahey, Closed vessel for isolating target molecules and for performing amplification.
  5. Gerdes John C., Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles.
  6. Stanley Christopher J. (Cambridgeshire GBX), Device for analytical determinations.
  7. Columbus Richard L. (Rochester NY), Gravity assisted collection device.
  8. Cottingham Hugh V. (Caldwell NJ), Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay.
  9. McMahon Michael E. (Libertyville IL) Gordon Julian (Lake Bluff IL), Method and device for improved reaction kinetics in nucleic acid hybridizations.
  10. Snitman David L. (Boulder CO) Stroupe Stephen D. (Libertyville IL), Method and kit for performing nucleic acid hybridization assays.
  11. Rosemeyer Viola,DEX ; Seibl Rudolf,DEX, Method for the detection of target nucleic acid.
  12. Cole Francis X. (Stow MA) Sigillo Eric C. (Methuen MA) MacDonnell Paul C. (Bedford MA) Cicia Nancy J. (Wakefield MA), Porous strip form assay device method.
  13. Gerdes John C. ; Jankovsky Lynn D. ; Kozwich Diane L., Self-contained device integrating nucleic acid extraction amplification and detection.
  14. Kozwich Diane L. ; Gerdes John C., Self-contained device integrating nucleic acid extraction, amplification and detection.

이 특허를 인용한 특허 (32)

  1. Tang, Hamilton R.; De La Zerda, Adam; Li, Kenneth I.; Limtao, Kevin M.; Baldwin, Alan D.; Loney, Gregory C., Cartridge-based thermocycler.
  2. Finehout, Erin Jean; Puleo, Christopher Michael; Lenigk, Ralf; Nichols, Jason M.; Nelson, John, Detection of nucleic acid amplification in a porous substrate.
  3. Kelly, Colin, Detection window for molecular diagnostic device.
  4. Reed, Michael W.; Nanassy, Oliver Z., Device and method for extraction and analysis of nucleic acids from biological samples.
  5. Reed, Michael W.; Nanassy, Oliver Z., Device and method for extraction and analysis of nucleic acids from biological samples.
  6. Reed, Michael W.; Nanassy, Oliver Z.; Haydock, Paul V.; Sharma, Nigel Rudra; Bardell, Ronald L.; Hargrave, Perry, Device and method for extraction and analysis of nucleic acids from biological samples.
  7. Lee, Helen Hwai-an; Dineva, Magda Anastassova; Wisniewski, Craig Alan; Stankus, Phillip John, Device, system and method for processing a sample.
  8. Wisniewski, Craig, Device, system and method for processing a sample.
  9. Andreyev, Boris; Chu, Steven; Ciopyk, Brian; De La Zerda, Adam; Huang, Helen; Loney, Gregory; Swenson, David D., Devices and methods for molecular diagnostic testing.
  10. Andreyev, Boris; Moravick, Keith E.; Ciopyk, Brian; Briones, Victor; Loney, Gregory; De La Zerda, Adam; Ching, Jesus; Chu, Steven; Swenson, David; Huang, Helen, Devices and methods for molecular diagnostic testing.
  11. Andreyev, Boris; Moravick, Keith E.; Ciopyk, Brian; Briones, Victor; Loney, Gregory; de la Zerda, Adam; Ching, Jesus; Chu, Steven; Swenson, David; Huang, Helen, Devices and methods for molecular diagnostic testing.
  12. Andreyev, Boris; Moravick, Keith E.; Ciopyk, Brian; Briones, Victor; Loney, Gregory; de la Zerda, Adam; Ching, Jesus; Kelly, Colin; Chu, Steven; Swenson, David; Huang, Helen, Devices and methods for molecular diagnostic testing.
  13. Andreyev, Boris; Moravick, Keith E.; Ciopyk, Brian; Briones, Victor; Loney, Gregory; de la Zerda, Adam; Ching, Jesus; Kelly, Colin; Chu, Steven; Swenson, David; Huang, Helen, Devices and methods for molecular diagnostic testing.
  14. Reed, Michael W.; Nanassy, Oliver Z.; Haydock, Paul V.; Sharma, Nigel Rudra; Bardell, Ronald L.; Hargrave, Perry, Devices and processes for nucleic acid extraction.
  15. Reed, Michael W.; Gestwick, Daniel P., Gravity flow fluidic device for nucleic acid extraction.
  16. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Gravity-assisted mixing methods.
  17. Breidenthal, Scott S.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A.; Fan, Sara H., Gravity-assisted mixing methods.
  18. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Poirier, Michael S.; Scott, Matthew J.; Taylor, Jason A., Instruments and methods for exposing a receptacle to multiple thermal zones.
  19. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Instruments and methods for mixing the contents of a detection chamber.
  20. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Instruments and methods for mixing the contents of a detection chamber.
  21. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Instruments and methods for mixing the contents of a detection chamber.
  22. Fan, Sara H.; Lee, Richard S., Instruments for mixing the contents of a detection chamber.
  23. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Methods and instruments for processing a sample in a multi-chambered receptacle.
  24. Nelson, Norman C.; Roma, Gianluca, Methods for manipulating liquid substances in multi-chambered receptacles.
  25. Nelson, Norman C.; Roma, Gianluca, Methods for manipulating liquid substances in multi-chambered receptacles.
  26. Breidenthal, Scott S.; Fan, Sara H.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Methods of concentrating an analyte.
  27. Kelly, Colin; Briones, Victor, Molecular diagnostic device.
  28. Baker, Tony, Removal of molecular assay interferences.
  29. Kelly, Colin, Status indicator for molecular diagnostic device.
  30. Jenison, Robert Delmar, Systems and methods for point-of-care amplification and detection of polynucleotides.
  31. Hellyer, Tobin; Fort, Thomas; McMillian, Ray A., Use of an extraction control in a method of extracting nucleic acids.
  32. Hellyer,Tobin; Fort,Thomas; McMillian,Ray A., Use of an extraction control in a method of extracting nucleic acids.
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