IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
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출원번호 |
US-0848064
(2001-05-03)
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발명자
/ 주소 |
- Edelberg, Jay M.
- Christini, David J.
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출원인 / 주소 |
- Cornell Research Foundation, Inc.
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대리인 / 주소 |
Schwagman, Lundberg, Woessner & Kluth, P.A.
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인용정보 |
피인용 횟수 :
21 인용 특허 :
5 |
초록
▼
The present invention provides implantable physiological or pathophysiological biosensors. The subject biosensors comprise tissue or cells capable of carrying out a physiological or pathophysiological function, which can be used to monitor a chemical, physiological or pathophysiological variable ass
The present invention provides implantable physiological or pathophysiological biosensors. The subject biosensors comprise tissue or cells capable of carrying out a physiological or pathophysiological function, which can be used to monitor a chemical, physiological or pathophysiological variable associated with the physiological or pathophysiological function. In one embodiment, the tissue or cells are coupled via an electrical interface to an electronic measuring device or an electronic amplifying device. In another embodiment, the tissue or cells are coupled via an electrical interface to endogenous tissue or cells, including the blood. Preferably, the tissue or cells are excitable tissue or cells such as cardiac tissue or cells and neuronal tissue or cells. The subject biosensors may be placed, inserted or implanted in any animal including but not limited to a mouse, rat, rabbit, pig, cat, dog, cattle, horse, sheep or human. The present invention also provides various methods which employ a biosensor of the present invention. Such methods include a method of monitoring physiological or pathophysiological function, a method of regulating output of a signal to a subject, and a method for controlling heart function.
대표청구항
▼
The present invention provides implantable physiological or pathophysiological biosensors. The subject biosensors comprise tissue or cells capable of carrying out a physiological or pathophysiological function, which can be used to monitor a chemical, physiological or pathophysiological variable ass
The present invention provides implantable physiological or pathophysiological biosensors. The subject biosensors comprise tissue or cells capable of carrying out a physiological or pathophysiological function, which can be used to monitor a chemical, physiological or pathophysiological variable associated with the physiological or pathophysiological function. In one embodiment, the tissue or cells are coupled via an electrical interface to an electronic measuring device or an electronic amplifying device. In another embodiment, the tissue or cells are coupled via an electrical interface to endogenous tissue or cells, including the blood. Preferably, the tissue or cells are excitable tissue or cells such as cardiac tissue or cells and neuronal tissue or cells. The subject biosensors may be placed, inserted or implanted in any animal including but not limited to a mouse, rat, rabbit, pig, cat, dog, cattle, horse, sheep or human. The present invention also provides various methods which employ a biosensor of the present invention. Such methods include a method of monitoring physiological or pathophysiological function, a method of regulating output of a signal to a subject, and a method for controlling heart function. system is adapted to identify the resistance of the resistor member upon electrical contact between the resistor member and the electrical circuit and wherein the sensor system is adapted to communicate a fault signal to a processor if the container is an incorrect configuration; and an electrically conductive leaf spring to conducts electricity between the container and the electrical circuit. 2. The container of claim 1, wherein the plastic body is non-conductive. 3. The container of claim 1, wherein the resistor member is attached to the outside surface of the body. 4. The container of claim 1, wherein the resistor member is embedded in the wall of the body. 5. The container of claim 1, wherein the resistor member is located internal in the body and includes contacts extending from the resistor member to the outside of the body. 6. The container of claim 1, wherein the container is a toner bottle. 7. The container of claim 1, wherein the container is a process cartridge. 8. The container of claim 7, wherein the process cartridge is fittable to a developer unit in an electrophotographic apparatus. 9. The container of claim 1, wherein the resistor member is a strip of conductive material of selected resistance. 10. The container of claim 1, wherein the sensor system is adapted to communicate a fault signal when the resistor member has a resistance value outside a selected target range. 11. The container of claim 1, wherein the sensor system is adapted for configuration identification of toner containers. 12. The container of claim 1, wherein the sensor system includes a window comparator electrical circuit including a range of allowable resistance values for comparison against the selected resistance of the resistor member on the container. 13. The container of claim 1, wherein the sensor system is adapted to send a fault signal to a selected printing or copying apparatus if the resistance in the resistor member is not within the range programmed in the window comparator circuit after the container is installed in the selected printing or copying apparatus. 14. A container for containing a supply of toner particles, comprising: a plastic body defining a wall, an outside surface, and a chamber, the chamber for storing particles therein, the body made of a first material; and a resistor member having a length, width, thickness, and selected resistance value attached to the body, the resistor member made of a second material and being permanently attached to the body; wherein the resistor member is made of an electrically conductive material and is made of a material different than the body; a developer unit; a sensor system functionally associated with the developer unit; and an electrical circuit functionally associated with the sensor system wherein the sensor system is adapted to identify the resistance of the resistor member upon electrical contact between the resistor member and the electrical circuit and wherein the sensor system is adapted to communicate a fault signal to a processor if the container is an incorrect configuration; wherein the container is a process cartridge and wherein an electrically conductive spring associated with the developer unit housing opens the electrical circuit on the voltage line when there is no toner bottle in the process cartridge and acts as an interlock to kill the high voltage power supply. 15. A container for containing a supply of toner particles, comprising: a plastic body defining a wall, an outside surface, and a chamber, the chamber for storing particles therein, the body made of a first material; and a resistor member having a length, width, thickness, and selected resistance value attached to the body, the resistor member made of a second material and being permanently attached to the body; wherein the resistor member is made of an electrically conductive material and is made of a material different than the body; a developer unit; a sensor system functiona lly associated with the developer unit; an electrical circuit functionally associated with the sensor system wherein the sensor system is adapted to identify the resistance of the resistor member upon electrical contact between the resistor member and the electrical circuit and wherein the sensor system is adapted to communicate a fault signal to a processor if the container is an incorrect configuration; wherein the container is a process cartridge and wherein an electrically conductive spring associated with the developer unit housing opens the electrical circuit on the voltage line when there is no process cartridge in the developer unit and acts as an interlock to kill the high voltage power supply. 16. The container of claim 15, wherein the resistor member is in the form of a functional feature including at least one of a ridge, channel, slide rail and protrusion associated with the wall of the container. 17. An electrophotographic apparatus comprising: a process cartridge including a wall, an outside surface, and a chamber, the chamber for storing particles therein; and a developing unit including a conductive spring member associated therewith, the spring member adapted to move from a first position when the process cartridge is operatively engaged and close an electrical circuit of a voltage line and adapted to move to a second position when the process cartridge is removed and open the electrical circuit; wherein in the second position the open electrical circuit on the voltage line eliminates the high voltage power supply to the electrophotographic apparatus wherein if the process cartridge is fitted in the developing unit, a low voltage circuit is closed utilizing a conductive connector to bridge the open circuit and wherein if the process cartridge is not fitted in the developing unit, the low voltage circuit is open causing a high voltage supply line to be open and the electrophotographic apparatus to be inoperable. 18. A method of determining the configuration of a container in a printing or copying apparatus comprising: providing a plastic container adapted for use in a developer unit, the container defining a wall, an outside surface, and a chamber; associating a resistor member with the plastic container, the resistor member having a length, width, thickness, and selected resistance value, the resistor member being made of an electrically conductive material; providing a sensor system and an electrical circuit adapted to identify a resistance value of the resistor member on the container when the resistor member is functionally associated with the electrical circuit; contacting the resistor member with the electrical circuit in conjunction with the container being functionally associated with a developer unit; identifying the resistance of the resistor member; communicating a fault signal when a container of incorrect configuration is associated with the developer unit, the signal being triggered based on the identified resistance of the resistor member being outside an allowed target range programmed in a window comparator circuit; and providing a conductive spring between the developer unit housing and the container; wherein if the container is fitted in the developer unit housing, a low voltage circuit is closed utilizing a conductive connector to bridge the open circuit and wherein if the container is not fitted in the developer unit housing, the low voltage circuit is open causing a high voltage supply line to be open and the printing or copying apparatus to be inoperable. 19. The method of claim 18, further comprising using the window comparator circuit to compare a programmed resistance range for a container in the printing or copying apparatus with the actual identified resistance of the resistor member on the container in the printing or copying apparatus. 20. The method of claim 18, further comprising loading the container into the printing and copying apparatus and providing a fau
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