IPC분류정보
| 국가/구분 |
United States(US) Patent
등록
|
| 국제특허분류(IPC7판) |
|
| 출원번호 |
US-0559139
(2000-04-27)
|
|
발명자
/ 주소 |
- Kollias, Nikiforos
- Gillies, Robert
- Tian, Wei Dong
|
| 출원인 / 주소 |
- The General Hospital Corporation
|
| 대리인 / 주소 |
Nutter McClennen & Fish LLP
|
| 인용정보 |
피인용 횟수 :
55 인용 특허 :
26 |
초록
▼
The present invention is directed to methods for treating acne. The methods include exposing the subject afflicted with acne to ultraviolet light having a wavelength between about 320 to about 350 nm, such that the acne is treated, e.g., inhibited, diminished, eradicated or prevented. In a preferred
The present invention is directed to methods for treating acne. The methods include exposing the subject afflicted with acne to ultraviolet light having a wavelength between about 320 to about 350 nm, such that the acne is treated, e.g., inhibited, diminished, eradicated or prevented. In a preferred embodiment, the wavelength is 335 nm and is emitted by either a nitrogen laser or a third harmonic of a NdYAG laser. Treatments can be administered over a several week period, where the subject is exposed to sequential doses of ultraviolet light to obtain beneficial effects, e.g., a reduction or elimination of the acne, e.g., an eradication or diminishment of the bacteria responsible for acne, e.g., Propionibacterium acnes.
대표청구항
▼
1. A method for treating acne, comprising exposing a region of skin of a subject afflicted with acne to ultraviolet light having wavelengths substantially contained in a spectral band between about 320 to about 360 nm, and a fluence of between about 1 J/cm2and about 5 J/cm2,so as to produce a bio
1. A method for treating acne, comprising exposing a region of skin of a subject afflicted with acne to ultraviolet light having wavelengths substantially contained in a spectral band between about 320 to about 360 nm, and a fluence of between about 1 J/cm2and about 5 J/cm2,so as to produce a biological response in a target within a layer of the region of skin that effectively enhances treatment of the acne without substantially damaging tissue surrounding the target while limiting overall dose of irradiation. 2. The method of claim 1, wherein said wavelengths are between about 325 to about 345 nm. 3. The method of claim 1, wherein said wavelengths are between about 330 to about 340 nm. 4. The method of claim 1, wherein said wavelengths are between 332 and 337 nm. 5. The method of claim 1, wherein said wavelengths are about 335 nm. 6. The method of claim 1, wherein said ultraviolet light is produced by a nitrogen laser. 7. The method of claim 1, wherein said ultraviolet light is produced by a third harmonic of a NdYAG laser. 8. The method of claim 1, wherein said treatment is performed at between about 0.1 to about 0.5 minimum erythema dose. 9. The method of claim 1, wherein said treatment is conducted over multiple exposure periods. 10. The method of claim 1, wherein said treatment comprises prevention of acne. 11. The method of claim 10, wherein said wavelength is between about 330 to about 340 nm. 12. The method of claim 11, wherein said wavelength is between 332 and 337 nm. 13. The method of claim 12, wherein said wavelength is about 335 nm. 14. The method of claim 1, wherein said treatment is effected to reduce size or amount of sebaceous glands in exposed skin. 15. The method of claim 14, wherein said treatment is performed at between about 0.1 to about 0.5 minimum erythema dose. 16. The method of claim 14, wherein said treatment is conducted over multiple exposure periods. 17. A method for treating acne, comprising exposing a region of skin of a subject afflicted with acne to ultraviolet light having wavelengths substantially contained in a spectral band between about 320 to about 360 nm, and a fluence of between about 1 J/cm2and about 5 J/cm2,so as to produce a biological response in a sebaceous gland within the region of skin that effectively enhances treatment of the acne without substantially damaging tissue surrounding the sebaceous gland while limiting overall dose of irradiation.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.