[특허]System and method for aerosol delivery of a drug

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61M-015/00
출원번호	US-0270508 (2002-10-16)
발명자 / 주소	Bibi, Noam Lev, Nimrod Landau, Eitan
출원인 / 주소	Medihale Ltd.
대리인 / 주소	Friedman, Mark M.
인용정보	피인용 횟수 : 2 인용 특허 : 38

초록 ▼

A system and method for aerosol delivery of a drug. The system includes: a disposable cassette containing a dose of the drug. The dose of the drug is supplied within a breakable container. The system further includes a drug release mechanism to break the breakable container and release dose of the d

A system and method for aerosol delivery of a drug. The system includes: a disposable cassette containing a dose of the drug. The dose of the drug is supplied within a breakable container. The system further includes a drug release mechanism to break the breakable container and release dose of the drug. Air from the airflow generator flows into the cassette via a first opening and outward via a second opening insuring aerosol delivery of the drug. The method includes supplying a disposable cassette as in the system and operating a drug release mechanism to break the breakable container and release the dose of the drug. The method further includes generating a flow of air top cause aerosol delivery of the drug. An additional method including supplying at least two breakable packets each containing a portion of a pre-measured dose of the drug within a disposable cassette, opening the packets within the cassette and aerosol delivery of the single pre-measured dose of the drug.

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A system and method for aerosol delivery of a drug. The system includes: a disposable cassette containing a dose of the drug. The dose of the drug is supplied within a breakable container. The system further includes a drug release mechanism to break the breakable container and release dose of the d

A system and method for aerosol delivery of a drug. The system includes: a disposable cassette containing a dose of the drug. The dose of the drug is supplied within a breakable container. The system further includes a drug release mechanism to break the breakable container and release dose of the drug. Air from the airflow generator flows into the cassette via a first opening and outward via a second opening insuring aerosol delivery of the drug. The method includes supplying a disposable cassette as in the system and operating a drug release mechanism to break the breakable container and release the dose of the drug. The method further includes generating a flow of air top cause aerosol delivery of the drug. An additional method including supplying at least two breakable packets each containing a portion of a pre-measured dose of the drug within a disposable cassette, opening the packets within the cassette and aerosol delivery of the single pre-measured dose of the drug. ein the spool piece comprises a generally cylindrical construction, and wherein the plurality of sensor receptacles are formed through a side surface thereof. 3. An automatic data logging kit according to claim 1, wherein the spool piece comprises an isolation valve. 4. An automatic data logging kit according to claim 1, wherein the end connectors are quick flanges. 5. An automatic data logging kit for use with a hydraulic integrity test skid for testing a liquid cooled stator bar system, the automatic data logging kit comprising: a spool piece including end connectors attachable between the liquid cooled stator bar system and the hydraulic integrity test skid and a plurality of sensor receptacles; at least one temperature sensor insertable within an interior of the liquid cooled stator bar system and having an output connector operatively securable in a first of the sensor receptacles; at least one pressure sensor operatively securable in a second of the sensor receptacles; and a control unit receiving output from the at least one temperature sensor and the at least one pressure sensor, the control unit calculating a leak rate based on the received sensor output, wherein the at least one temperature sensor comprises a temperature probe insertable within the interior of the liquid cooled stator bar system, the temperature probe comprising multiple sensor zones spaced along a length of the temperature probe. 6. An automatic data logging kit according to claim 5, wherein each of the multiple sensor zones comprises multiple temperature sensors. 7. An automatic data logging kit according to claim 6, comprising multiple pressure sensors operatively securable in at least one respective sensor receptacle. 8. An automatic data logging kit according to claim 7, wherein the control unit determines data points for calculating the leak rate, the data points being an average of outputs from the multiple temperature sensors of each sensor zone and outputs from the multiple pressure sensors. 9. An automatic data logging kit according to claim 8, wherein the control unit is configured to determine whether any of the temperature sensors and the pressure sensors is faulty based on a comparison of respective outputs. 10. An automatic data logging kit according to claim 1, comprising multiple pressure sensors operatively securable in respective sensor receptacles. 11. An automatic data logging kit according to claim 1, wherein the control unit is configured to calculate the leak rate using a pressure-decay test based on the received sensor output according to: where: L=Leak Rate (ft3/day) V=Test Volume (ft3) H=Time into Test (Hours) B1, B2=Initial (B1) and Final (B2) atmospheric pressure ("Hg) M1, M2=Initial (M1) and Final (M2) winding pressure ("Hg) T1, T2=Initial (T1) and Final (T2) winding temperature (° C). 12. An automatic data logging kit according to claim 1, wherein the control unit is configured to calculate the leak rate using a vacuum-decay test based on the received sensor output according to: where: L=Leak Rate (ft3/day) P=Change in Pressure, P2-P1, (Microns) T=Time into test (Hours) V=Test volume (ft3). 13. An automatic data logging kit according to claim 1, wherein the control unit designates the leak rate as PASS or FAIL according to predefined conditions. 14. An automatic data logging kit according to claim 13, wherein the control unit factors in sensor and hardware tolerances and linearity effects to calculate the leak rate and to designate the leak rate as PASS or FAIL. 15. An automatic data logging kit for use with a hydraulic integrity test skid for testing a liquid cooled stator bar system, the automatic data logging kit comprising: a spool piece installable between the liquid cooled stator bar system and the hydraulic integrity test skid, the spool piece including end connectors attachable between the liquid cooled stator bar system and the hydra

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이 특허에 인용된 특허 (38) 인용/피인용 타임라인 분석

Keith Alec D. (Miami FL), Anti-spilling drug capsule.
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Smith Adrian E. ; Burr John D. ; Etter Jeffrey W. ; Axford George S. ; Anthony Jack M., Apparatus and methods for dispersing dry powder medicaments.
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Rosskamp Gunter (Berlin DEX) Kolberg Reiner (Berlin DEX) Gunzel Peter (Berlin DEX) Porep Hans-Jurgen (Berlin DEX), Apparatus for the inhalation of medicinal agents.
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Rosskamp Gunter (Berlin DT) Kolberg Reiner (Berlin DT) Gunzel Peter (Berlin DT) Porep Hans-Jurgen (Berlin DT), Apparatus for the inhalation of medicinal agents.
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David J. Krajewski ; Thomas D. Canup, Autopriming a micro-cassette while minimizing the formation of air bubbles in a pumping chamber.
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Ernst Horlin SE, Capsule opening arrangement for use in a powder inhaler.
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Firestone Bruce A. ; Tran Thao T., Capsule system.
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Wright David M. (Evansville IN), Dispensing package.
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Jacobsen Stephen C. ; Best Aaron M. ; Petelenz Tomasz J. ; Sinnott M. Mary, Disposable fluid injection module.
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Wong Patrick S. L. ; Theeuwes Felix ; Ferrari Vincent J. ; Dong Liang C., Dosage form comprising a capsule.
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Evans Rix E. (Wendell NC), Dosage inhalator with air flow velocity regulating means.
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Palti Yoram (51 Ruth Street Haifa 34404 ILX), Drug coding and delivery system.
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Stimpson Philip G. (Welford GBX), Drug dispensing system.
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DeJonge, Stuart, Dry powder dispenser.
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Casper Robert A. ; Leith Frank A. ; Gardner David L., Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery.
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Mulhauser Paul (New York NY) Karg Jeffrey (Waldwick NY) Foxen Thomas (Brooklyn NY) Brooks Christopher J. (Glen Head NY), Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same.
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Noam Bibi IL, Dual-purpose medical device for upper airway treatment and methods for using same.
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Williams Harold R. (Capistrano Beach CA) Spencer Robert M. (San Juan Capistrano CA), Fluid injection system cassette and fluid packaging methods.
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Abrams Andrew L. (26 Imperial Ave. Westport CT 06880) Gumaste Anand (7 Ardsley Ct. Robbinsville NJ 08691), Inhalation device.
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Abrams Andrew L. ; Gumaste Anand V., Inhalation device.
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Ohki, Hisatomo; Yazawa, Yoshiyuki; Nakamura, Shigemi; Yokobori, Mitsuru; Ishizeki, Kazunori, Inhalator for administering powder composition.
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Schwab Egon (Hochheim am Main DEX) Loos Hans-Joachim (Ginsheim-Gustavsburg DEX) Ziegert Gnter (Frankfurt am Main DEX), Inhaler.
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Malcher Eric (St. Louis FRX) Zechner Kurt (Allschwil CHX), Inhaler for administration of powdery substances.
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Cocozza Salvatore (Milan ITX), Insufflator for the administration of drugs in the form of a powder pre-dosed into opercola.
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Mangini Richard J. (Redwood City CA) Hartig William J. (Pleasanton CA), Kit for distributing pharmaceutical products.
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Mangini Richard J. (Redwood City CA) Hartig William J. (Pleasanton CA), Kit for distributing pharmaceutical products.
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Rex Jrn (Roskilde DKX), Manually operated dispenser for dispensing a predetermined amount of powdered substance.
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Damani Nalinkant C. (Mountain View CA), Medicament dispensing process for inhalation therapy.
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Artis R. Lockhart ; Vincent J. Sullivan ; Lawrence A. Monahan ; Anjana Bhuta Wills, Medicament respiratory delivery device.
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Ohki Hisatomo,JPX ; Nakamura Shigemi,JPX ; Ishizeki Kazunori,JPX ; Yanagawa Akira,JPX, Medicator for a capsule filled with a powdered drug.
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Ohki Hisatomo,JPX ; Nakamura Shigemi,JPX ; Ishizeki Kazunori,JPX ; Yazawa Yoshiyuki,JPX ; Yanagawa Akira,JPX, Medicine administering device for nasal cavities.
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Stefan Kafer DE, Medium dispenser.
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Weston Terence Edward,GBX ; Walker John Nicholas,GBX, Method of filling a drug capsule and article produced thereby.
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Makino Yuji (Tokyo JPX) Suzuki Yoshiki (Tokyo JPX), Multi-dose powdered medicine administering device and method thereof.
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Itaya Kozo (Sakai JPX) Nishida Hirotaka (Minoo JPX) Fukuda Kazutoshi (Ichihara JPX), Packaging structure.
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Bruna Pascal (Rouen FRX) Brunet Michel (Sainte-Colombe-La-Commanderie FRX 4), Powder inhaler with suction actuated locking means.
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Sneider Vincent R. (3422 Hallcrest Dr. ; N.E. Atlanta GA 30319), Tampon and drug delivery device.
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Pike Gregory Charles,AUX ; Riedel Ingo Helmuth,AUX ; Smith Stephan,AUX, Unit dose dispensing device.
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이 특허를 인용한 특허 (2) 인용/피인용 타임라인 분석

Century, Theodore J., Apparatus and method for aerosol delivery to the lungs or other locations of the body.
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LaValley, Patrick, Package for chemicals.
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[미국특허] System and method for aerosol delivery of a drug 원문보기

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