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특허 상세정보

Method and compositions for regulation of 5-alpha reductase activity

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-031/35   
미국특허분류(USC) 514/456; 514/337; 514/453; 514/455; 514/457; 514/532; 514/544; 514/557; 514/558; 514/617; 514/622; 514/646; 514/655; 514/678; 514/680; 514/681; 514/682; 514/683; 514/679; 514/720; 514/729; 514/731; 5
출원번호 US-0132050 (2002-04-24)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Mahoney, Joseph A.Rebman, Christine M.Mayer Brown Rowe & Maw LLP
인용정보 피인용 횟수 : 31  인용 특허 : 20
초록

Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5α-reductase inhibitor, such as natural and synthetic flavanoids, catechols, curcumin-related substances, quinones, catechins, particularly epigallocatechin derivatives, fatty acids, and the salts, esters, analogues, pro-drugs, isomers, racemic mixtures, or derivatives of any of the foregoing. The use of testosterone (or DHT) combinations with the aforementioned 5α-reductase inhibitor compounds is also contemplated.

대표
청구항

Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5α-reductase inhibitor, such as natural and synthetic flavanoids, catechols, curcumin-related substances, quinones, catechins, particularly epigallocatechin derivatives, fatty acids, and the salts, esters, analogues, pro-drugs, isomers, racemic mixtures, or derivatives of any of the foregoing. The use of testosterone (or DHT) combinations with the aforementioned 5α-reductase inhibitor compounds is also contemplated. kenyloxy, alk...

이 특허에 인용된 특허 (20)

  1. Togasaki Keiichi,JPX. Active oxygen free radical scavenging agent. USP1998085788971.
  2. Lanzendorfer Ghita,DEX ; Stab Franz,DEX ; Untiedt Sven,DEX. Agents acting against hyperreactive and hypoactive, deficient skin conditions and manifest dermatitides. USP2001016180662.
  3. Bissett Donald Lynn. Compositions for regulating skin appearance. USP2000076093411.
  4. Vacher Anne-Marie,FRX ; Fritsch Marie-Claire,FRX. Cosmetic composition exploiting synergistic radical scavenging effects. USP2001056231877.
  5. N\Guyen Quang-Lan (Antony FRX). Cosmetic or pharmaceutical composition containing a combination of a polyphenol and a ginkgo extract. USP1997115686082.
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  7. Eric Perrier FR; Anne-Marie Mariotte FR; Ahcene Boumendjel FR; Delphine Bresson-Rival FR. Flavonoide esters and their use notably in cosmetics. USP2002106471973.
  8. Chen Sophie (Millwood NY) Wang Xuhui (Shanghai CNX). Herbal composition for treating prostate carcinoma. USP1997095665393.
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  10. Mark Empie ; Eric Gugger. Method of preparing and using isoflavones for the treatment of cancer. USP2002056395279.
  11. Carey John,NLX ; Ellis Jayne Elizabeth,GBX ; Austin Corrine Jane,GBX. Method of reducing or preventing malodour. USP2001026183731.
  12. Anderson Jon ; Matsui Mary Steidl. Method of treating topical angiogenesis-related disorders. USP2001066248341.
  13. Liao Shutsung (Chicago IL) Liang Tehming (Centerville OH). Methods and compositions for inhibiting 5a
  14. Liao Shutsung (Chicago IL) Liang Tehming (Centerville OH). Methods and compositions for inhibiting 5a
  15. Cheng Shu Jun,CNX ; Wang De Chang,CNX ; Hara Yukihiko,JPX ; Lee Insu P.,KRX ; Ahn Woong Shick,KRX. Methods for treating hyperplasia. USP2001036197808.
  16. Murad Howard. Pharmaceutical compositions and methods for improving wrinkles and other skin conditions. USP1998095804594.
  17. Murad Howard. Pharmaceutical compositions and methods for protecting and treating sun damaged skin. USP1998095804168.
  18. Murad Howard. Pharmaceutical compositions and methods for treating acne. USP1999105962517.
  19. Theodore Hersh ; Michael A. Warshaw. Reparatives for ultraviolet radiation skin damage. USP2002016337320.
  20. Burger Allan Robert (Passaic NJ) Granger Stewart Paton (Paramus NJ) Scott Ian Richard (Allendale NJ). Skin care compositions containing naringenin and/or quercetin and a retinoid. USP1997095665367.

이 특허를 인용한 특허 피인용횟수: 31

  1. Chan, Tak-Hang; Lam, Wai-Har; Chow, Larry Ming-Cheung; Dou, Qing Ping; Kuhn, Deborah Joyce; Kazi, Aslamuzzaman; Wan, Sheng Biao; Landis-Piwowar, Kristin R.. (−)-Epigallocatechin gallate derivatives for inhibiting proteasome. USP2015109169230.
  2. Chan, Tak-Hang; Lam, Wai-Har; Chow, Larry Ming-Cheung; Dou, Qing Ping; Kuhn, Deborah Joyce; Kazi, Aslamuzzaman; Wan, Sheng Biao; Landis-Piwowar, Kristin R.. (−)-epigallocatechin gallate derivatives for inhibiting proteasome. USP2014048710248.
  3. Guthery, B. Eugene. Acne vulgaris treatment regimen. USP2012118313782.
  4. Guthery, B. Eugene. Acne vulgaris treatment regimen. USP2014038679552.
  5. Fast, David J.; Patterson, Jennifer; Rajgopal, Arun; Pusateri, Donald J.; Gellenbeck, Kevin W.; Scholten, Jeffrey; Missler, Stephen R.; Randolph, Russell K.; Chuang, Jennifer; Lin, Yumei; Kazlova, Valiantsina. Antioxidant dietary supplement and related method. USP20190210201583.
  6. Fast, David J.; Patterson, Jennifer; Rajgopal, Arun; Pusateri, Donald J.; Gellenbeck, Kevin W.; Scholten, Jeffrey; Missler, Steven R.; Randolph, Russell K.; Chuang, Jennifer; Lin, Yumei; Kazlova, Valiantsina. Antioxidant dietary supplement and related method. USP2016129517249.
  7. Hsia, Sung Lan; Narain, Niven Rajin; Li, Jie; Russell, Kathryn J.; Woan, Karrune V.; Persaud, Indushekhar. Co-enzyme Q10 formulations and methods of use. USP2013108562976.
  8. Hsia, Sung Lan; Narain, Niven Rajin; Li, Jie; Russell, Kathryn J.; Woan, Karrune V.; Persaud, Indushekhar. Co-enzyme Q10 formulations and methods of use. USP2013118586030.
  9. Salentine, Christopher G.; O'Donoghue, Kieran. Formulations of vitamin K analogs for topical use. USP2014088815953.
  10. Wang,Shaomeng; Chen,Jiangyong. Gossypol co-crystals and the use thereof. USP2008037342046.
  11. Wang,Shaomeng; Chen,Jiangyong. Gossypol co-crystals and the use thereof. USP2008107432300.
  12. Van De Winkel, Jan G. J.; Van Dijk, Marcus Antonius; Halk, Edward; Gerritsen, Arnout F.; Petersen, Jørgen; Baadsgaard, Ole. Human monoclonal antibodies to epidermal growth factor receptor (EGFR). USP2016109458236.
  13. Chang, Yunik; Lathrop, Robert; Böhm, Erwin; Gander-Meisterernst, Irene; Greger, Regina; Holldack, Johanna; Moebius, Ulrich. Medicament for the treatment of viral skin and tumour diseases. USP2010127858662.
  14. Chang, Yunik; Lathrop, Robert; Böhm, Erwin; Gander-Meisterernst, Irene; Greger, Regina; Holldack, Johanna; Moebius, Ulrich. Medicament for the treatment of viral skin and tumour diseases. USP2017099770406.
  15. Edvardsen, Klaus; Lisby, Steen; Baadsgaard, Ole. Method of treating rash in patients undergoing anti-EGFR therapy. USP2016089428582.
  16. Narain, Niven Rajin; McCook, John Patrick. Methods for treatment of oncological disorders using an epimetabolic shifter (coenzyme Q10). USP2018029896731.
  17. Narain, Niven Rajin; Sarangarajan, Rangaprasad; Gray, Thomas Mitchell; McCook, John Patrick; Jimenez, Joaquin J.. Methods of treatment of cancer by continuous infusion of coenzyme Q10. USP2018029901542.
  18. Amory,John K.; Bremner,William J.. Oral androgen therapy using modulators of testosterone bioavailability. USP2006117138389.
  19. Pilgaonkar, Pratibha; Rustomjee, Maharukh; Gandhi, Anilkumar; Bagde, Pradnya M.. Orally disintegrating tablets. USP2013108545890.
  20. Dudley, Robert E.; Drouin, Dominique. Pharmaceutical composition and method for treating hypogonadism. USP2015099132089.
  21. Dudley, Robert E.; Drouin, Dominique. Pharmaceutical composition and method for treating hypogonadism. USP2015099125816.
  22. Hsia, Sung Lan; Narain, Niven Rajin; Li, Jie; Russell, Kathryn J.; Woan, Karrune V.; Persaud, Indushekhar. Topical co-enzyme Q10 formulations and methods of use. USP2014078771680.
  23. Hsia, Sung Lan; Narain, Niven Rajin; Li, Jie; Russell, Kathryn J.; Woan, Karrune V.; Persaud, Indushekhar. Topical co-enzyme Q10 formulations and methods of use. USP2012048147825.
  24. McCook, John Patrick; Persaud, Indushekhar; Narain, Niven Rajin. Topical formulations having enhanced bioavailability. USP2013068454945.
  25. Borgström, Per. Treatment of prostate carcinoma. USP20190410245240.
  26. Stockfleth, Eggert. Use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin. USP2015069060998.
  27. Stockfleth, Eggert. Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin. USP2013068455022.
  28. Troplin, Philippe; Bernaert, Herwig. Use of cocoa polyphenols for treating a prostate hyperplasia, a specific cocoa extract and applications. USP2013058435576.
  29. Duranton, Albert; Breton, Lionel. Use of taurine for treating alopecia. USP2015099138408.
  30. Perez-Soler, Roman; Ling, Yi-He. Vitamin K for prevention and treatment of skin rash secondary to anti-EGFR therapy. USP2010067745494.
  31. Perez-Soler, Roman; Ling, Yi-He. Vitamin K for prevention and treatment of skin rash secondary to anti-EGFR therapy. USP2012108283382.