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Methods and products related to genotyping and DNA analysis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C12P-019/34
  • C07H-021/04
  • G01N-033/48
출원번호 US-0404912 (1999-09-24)
발명자 / 주소
  • Landers, John
  • Jordan, Barbara
  • Housman, David E.
  • Charest, Alain
출원인 / 주소
  • Massachusetts Institute of Technology
대리인 / 주소
    Wolf, Greenfield and Sacks, P.C.
인용정보 피인용 횟수 : 45  인용 특허 : 86

초록 ▼

The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligon

대표청구항 ▼

The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligon

이 특허에 인용된 특허 (86)

  1. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA), Active programmable electronic devices for molecular biological analysis and diagnostics.
    상세보기
  2. Wallace R. Bruce (Greenbrae CA) Pal Bijay K. (Arcadia CA) Ugozzoli Luis A. (San Rafael CA) Wu Dan Y. (Bellevue WA), Allele specific polymerase chain reaction.
    상세보기
  3. Johnston Richard F. ; Trounstine Mary, Aminosilane/carbodiimide coupling of DNA to glass substrate.
    상세보기
  4. Ward David C. ; Lichter Peter,DEX, Amplification karyotyping.
    상세보기
  5. Hartley James L. (Frederick MD), Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers.
    상세보기
  6. Hartley James L. (Frederick MD) Berninger Mark S. (Gaithersburg MD), Amplification of nucleic acid sequences using oligonucleotides of random sequences as primers.
    상세보기
  7. McClelland Michael (Del Mar CA) Welsh John T. (Leucadia CA) Sorge Joseph A. (Rancho Santa Fe CA), Arbitrarily primed polymerase chain reaction method for fingerprinting genomes.
    상세보기
  8. McClelland Michael ; Welsh John Thomas ; Sorge Joseph A., Arbitrarily primed polymerase chain reaction method for fingerprinting genomes.
    상세보기
  9. Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Array of oligonucleotides on a solid substrate.
    상세보기
  10. Fodor Stephen P.A. ; Stryer Lubert ; Read J. Leighton ; Pirrung Michael C., Arrays of materials attached to a substrate.
    상세보기
  11. Shi Jufang ; Boyce-Jacino Michael T., Attachment of unmodified nucleic acids to silanized solid phase surfaces.
    상세보기
  12. Lincoln Stephen E. ; Knapp Michael R., Automatic genotype determination.
    상세보기
  13. Groet Suzanne (Sudbury MA) Ostman Jonathan (Boston MA) Wydro Robert (Framingham MA), Binding nucleic acid to a support.
    상세보기
  14. Sapolsky Ronald J. ; Lipshutz Robert J. ; Gingeras Thomas R., Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping.
    상세보기
  15. Matson Robert S., Carboxylated polyvinylidene fluoride solid supports for the immobilization of biomolecules and methods of use thereof.
    상세보기
  16. Pinkel Daniel ; Gray Joe W. ; Kallioniemi Anne,FIX ; Kallioniemi Olli-Pekka,FIX ; Waldman Frederic, Comparative genomic hybridization.
    상세보기
  17. Santamaria Pedro (Minneapolis MN) Boyce-Jacino Michael T. (Saint Paul MN) Barbosa Jose J. (Roseville MN) Rich Stephen S. (Saint Paul MN) Faras Anthony J. (Long Lake MN), DNA sequence-based HLA typing method.
    상세보기
  18. Heller Michael J. ; Tu Eugene, Deoxyribonucleic acid(DNA) optical storage using non-radiative energy transfer between a donor group, an acceptor group.
    상세보기
  19. Barany Francis ; Lubin Matthew, Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions.
    상세보기
  20. Schalling Martin (Spanga SEX) Hudson Thomas J. (Arlington MA) Housman David E. (Newton MA), Direct detection of expanded nucleotide repeats in the human genome.
    상세보기
  21. Shuber Anthony P., Direct sequence identification of mutations by cleavage- and ligation-associated mutation-specific sequencing.
    상세보기
  22. Pena Sergio D. J. (Gene Av. Afonso Pena 3111/9 30130-909 Belo Horizonte ; MG BRX) Simpson Andrew J. G. (Belo Horizonte BRX), Fingerprinting using single specific primers in low stringency polymerase chain reaction conditions.
    상세보기
  23. White Raymond L. (Salt Lake City UT) Nakamura Yusuke (Salt Lake City UT) O\Connell Peter (Midvale UT) Leppert Mark F. (Salt Lake City UT), Genetic identification employing DNA probes of variable number tandem repeat loci.
    상세보기
  24. Amouyel Philippe,FRX ; Chartier-Harlin Marie-Christine,FRX, Genetic markers used jointly for the diagnosis of Alzheimer's disease, and diagnostic method and kit.
    상세보기
  25. Shuber Anthony P., High throughput screening method for sequences or genetic alterations in nucleic acids.
    상세보기
  26. Shuber Anthony P., High throughput screening method for sequences or genetic alterations in nucleic acids.
    상세보기
  27. Shuber Anthony P., High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segment.
    상세보기
  28. Shuber Anthony P. (Millford MA), High-throughput screening method for sequence or genetic alterations in nucleic acids using elution and sequencing of co.
    상세보기
  29. Higuchi Russell G., Homogeneous methods for nucleic acid amplification and detection.
    상세보기
  30. Heller Michael J. (Encinitas CA), Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to donor energy transfe.
    상세보기
  31. Hoffman Allan S. (Seattle WA) Dong Liang C. (Seattle WA), Immobilized biomolecules and method of making same.
    상세보기
  32. Hoffman, Allan S.; Dong, Liang C., Immobilized biomolecules and method of making same.
    상세보기
  33. Housman David E. (Newton MA), Inhibitors of alternative alleles of genes as a basis for cancer therapeutic agents.
    상세보기
  34. Munroe David J. (Somerville MA) Housman David E. (Newton MA), Interspersed repetitive element-bubble amplification of nucleic acids.
    상세보기
  35. Simons Malcolm J. (Fryerstown NZX), Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes.
    상세보기
  36. Nikiforov Theo (Baltimore MD) Karn Jonathan (Little Shelord GBX) Goelet Philip (Cockeysville MD), Ligase/polymerase mediated genetic bit analysis of single nucleotide polymorphisms and its use in genetic analysis.
    상세보기
  37. Fodgaard Henrik,DKX ; Singer Rolf,DKX ; Fabricius Paul Erik,DKX, Method and an apparatus for determining the content of a constituent of blood of an individual.
    상세보기
  38. Lacroix Jean-Michel,CAX ; Dunn James M.,CAX, Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample.
    상세보기
  39. Leushner James,CAX ; Hui May,CAX ; Dunn James M.,CAX ; Larson Marina T., Method for amplification and sequencing of nucleic acid polymers.
    상세보기
  40. Silver Jonathan (Bethesda MD) Feinstone Stephen (Washington DC), Method for amplifying unknown nucleic acid sequences.
    상세보기
  41. Soderlund Hans E.,FIX ; Syvanen Anne-Christine,FIX, Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators.
    상세보기
  42. Stevens John K.,CAX ; Dunn James M.,CAX ; Leushner James,CAX ; Green Ronald J.,CAX, Method for evaluation of polymorphic genetic sequences, and the use thereof in identification of HLA types.
    상세보기
  43. Nikiforov Theo T. (Baltimore MD) Knapp Michael R. (Baltimore MD), Method for generating single-stranded DNA molecules.
    상세보기
  44. Murphy Patricia D. ; White Marga B., Method for identifying variations in polynucleotide sequences.
    상세보기
  45. Nikiforov Theo (San Diego CA) Knapp Michael R. (Baltimore MD), Method for immobilizing nucleic acid molecules.
    상세보기
  46. Bertina Rogier Maria,NLX ; Reitsma Pieter Hendrik,NLX, Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response.
    상세보기
  47. Shuber Tony (Milford MA), Method for simultaneously detecting multiple mutations in a DNA sample.
    상세보기
  48. Frayne Elizabeth Gay, Method for single base-pair DNA sequence variation detection.
    상세보기
  49. Stevens John K. (Mississauga CAX) Dunn James M. (Scarborough CAX), Method for testing for mutations in DNA from a patient sample.
    상세보기
  50. Wallace R. Bruce, Method of detecting and discriminating between nucleic acid sequences.
    상세보기
  51. Rust Stephan,DEX ; Funke Harald,DEX ; Assmann Gerd,DEX ; Kessler Christoph,DEX ; Rueger Rudiger,DEX, Method of detecting variant nucleic acids using extension oligonucleotides which differ from each other at both a posit.
    상세보기
  52. Teasdale Robert D.,AUX, Method of random amplification of polymorphic DNA.
    상세보기
  53. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of sequencing of genoms by hybridization of oligonucleotide probes.
    상세보기
  54. Schon Eric A., Method to detect mutations in a nucleic acid using a hybridization-ligation procedure.
    상세보기
  55. Kwok Pui-Yan ; Chen Xiangning, Methods and kits for nucleic acid analysis using fluorescence resonance energy transfer.
    상세보기
  56. Saiki Randall K. (Richmond CA) Nasarabadi Shanavaz L. (Fremont CA), Methods and reagents for G-65 -globin typing.
    상세보기
  57. Haff Lawrence A. ; Smirnov Igor Pavlovich, Methods for determining sequences information in polynucleotides using mass spectrometry.
    상세보기
  58. Rabinovitch Peter S., Methods for making and using single-chromosome amplfication libraries.
    상세보기
  59. Brenner Sydney (Cambridge GB2), Methods for sorting polynucleotides using oligonucleotide tags.
    상세보기
  60. Amerson Henry V. ; Wilcox Phillip,NZX ; Sederoff Ronald R. ; Kuhlman E. George ; O'Malley David M. ; Grattapaglia Dario,BRX, Methods for within family selection of disease resistance in woody perennials using genetic markers.
    상세보기
  61. Malins Donald C., Methods of screening for a tumor or tumor progression to the metastatic state.
    상세보기
  62. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
    상세보기
  63. Fernandes Jorge, Multi-functional photometer with movable linkage for routing light-transmitting paths using reflective surfaces.
    상세보기
  64. Caskey Charles T. (Houston TX) Chamberlain Jeffrey S. (Houston TX) Gibbs Richard A. L. (Houston TX) Ranier Joel E. (Houston TX) Nguyen Phi N. (Houston TX), Multiplex genomic DNA amplification for deletion detection.
    상세보기
  65. Balch William J., Multiplexed molecular analysis apparatus and method.
    상세보기
  66. Caskey Charles T. (Houston TX) Gibbs Richard A. L. (Houston TX), Mutation detection by competitive oligonucleotide priming.
    상세보기
  67. Caskey Charles Thomas ; Gibbs Richard A. L., Mutation detection by competitive oligonucleotide priming.
    상세보기
  68. Fugono Nobutake,JPX ; Kurusu Yasurou,JPX ; Terasawa Masato,JPX ; Yukawa Hideaki,JPX, Oligonucleotide and method for analyzing base sequence of nucleic acid.
    상세보기
  69. Sorge Joseph A. (Rancho Santa Fe CA) Shoemaker Dan (Del Mar CA) Weiner Michael (San Diego CA), Oligonucleotide families useful for producing primers.
    상세보기
  70. Sorge Joseph A. (Rancho Santa Fe CA) Shoemaker Dan (Del Mar CA), Oligonucleotide libraries useful for producing primers.
    상세보기
  71. Rudert William A. (Sarver PA) Trucco Massimo (Pittsburgh PA), Polymers of oligonucleotide probes as the bound ligands for use in reverse dot blots.
    상세보기
  72. Sapolsky Ronald J. ; Lipshutz Robert J., Polymorphism detection.
    상세보기
  73. Chee Mark ; Fan Jian-Bing, Polymorphisms in the glucose-6 phosphate dehydrogenase locus.
    상세보기
  74. Halm Roland L. (Madison IN) Chadwick Kirk M. (Hanover IN) Keyes Brian R. (Salt Lake City UT), Preparation of organosilanes.
    상세보기
  75. Melanon Serge B. (Outremont CAX) Labuda Damian (Montreal CAX) Tang Jian Q. (Montreal CAX) Vanasse Michel (Ville Mont-Royal CAX), Primers and methods for simultaneous amplification of multiple markers for DNA fingerprinting.
    상세보기
  76. Sibson David Ross,GBX, Process for categorizing nucleotide sequence populations.
    상세보기
  77. Livak Kenneth J. (Wilmington DE) Rafalski Jan A. (Wilmington DE) Tingey Scott V. (Elkon MD) Williams John G. (Landenberg PA), Process for detecting polymorphisms on the basis of nucleotide differences.
    상세보기
  78. Erlich Henry A. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA) Mullis Kary B. (Kensington CA), Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids.
    상세보기
  79. Erlich Henry A. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA) Mullis Kary B. (Kensington CA), Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids.
    상세보기
  80. Cros Philippe (Lyons FRX) Allibert Patrice A. (Grezieu la Varenne FRX) Mandrand Bernard F. (Villeurbanne FRX) Dalbon Pascal T. (Venissieux FRX), Process for immobilizing a nucleic acid fragment by passive attachment to a solid substrate, the solid substrate thus ob.
    상세보기
  81. Stodolsky Marvin (Germantown MD), Purification of polymorphic components of complex genomes.
    상세보기
  82. Ronai Zeev A., Quantitative method for early detection of mutant alleles and diagnostic kits for carrying out the method.
    상세보기
  83. Bohlander Stefan K., Sequence independent amplification of DNA.
    상세보기
  84. Van Ness Jeffrey (Bothell WA) Petrie Charles R. (Woodinville WA) Tabone John C. (Bothell WA) Vermeulen Nicolaas M.J. (Woodinville WA) Reed Michael W. (Seattle WA), Solid supports for nucleic acid hybridization assays.
    상세보기
  85. Radoje T. Drmanac ; Snezana Drmanac, Three dimensional arrays for detection or quantification of nucleic acid species.
    상세보기
  86. McCasky Feazel Rhonda J. ; Helentjaris Timothy G. ; Malmberg Sharon E. ; Martin Barry A., Use of selective DNA fragment amplification products for hybridization-based genetic fingerprinting, marker assisted selection, and high-throughput screening.
    상세보기

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