Multi-part dental bleaching systems and methods for bleaching teeth using such systems
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-007/16
A61K-007/20
출원번호
US-0212381
(2002-08-05)
발명자
/ 주소
Allred, Peter M.
출원인 / 주소
Ultradent Products, Inc.
대리인 / 주소
Workman Nydegger
인용정보
피인용 횟수 :
4인용 특허 :
50
초록▼
Dental bleaching systems that include a bleaching component and a neutralizing component which, when mixed together, yield a mixed composition having a desired bleaching activity and gel properties. The bleaching composition includes a suitable bleaching agent, such as aqueous hydrogen peroxide, in
Dental bleaching systems that include a bleaching component and a neutralizing component which, when mixed together, yield a mixed composition having a desired bleaching activity and gel properties. The bleaching composition includes a suitable bleaching agent, such as aqueous hydrogen peroxide, in a concentration of about 3% to about 95% by weight of the bleaching composition component. The neutralizing component includes a strong particulate base mixed with a polymeric thickening agent. The neutralizing component is substantially water-free to prevent destruction of the gelling capability of the thickening agent by the base prior to formation of the mixed composition. The particulate base may include oxides, hydroxides or carbonates of alkali metals or alkaline earth metals. Maintaining the bleaching agent and neutralizing agent in separate components provides increased stability of both the bleaching agent and gelling (thickening) agent during storage and transport.
대표청구항▼
1. A multi-part dental bleaching system comprising: an aqueous dental bleaching composition that includes at least one dental bleaching agent and that has an acidic pH; and a substantially water free neutralizing composition suitable for mixing with the aqueous dental bleaching composition and
1. A multi-part dental bleaching system comprising: an aqueous dental bleaching composition that includes at least one dental bleaching agent and that has an acidic pH; and a substantially water free neutralizing composition suitable for mixing with the aqueous dental bleaching composition and that comprises at least one polymeric thickening agent mixed with at least one particulate base selected from the group consisting of metal oxides, metal hydroxides, ammonium hydroxide, and metal carbonates. 2. A multi-part dental bleaching system as defined in claim 1, the dental bleaching composition comprising at least about 20%, by weight of the system, of available hydrogen peroxide.3. A multi-part dental bleaching system as defined in claim 1, the dental bleaching composition comprising at least about 30%, by weight of the system, of available hydrogen peroxide.4. A multi-part dental bleaching system as defined in claim 1, the dental bleaching composition comprising at least about 40%, by weight of the system, of available hydrogen peroxide.5. A multi-part dental bleaching system as defined in claim 1, the dental bleaching composition having a pH of about 4 or less.6. A multi-part dental bleaching system as defined in claim 1, the dental bleaching composition having a pH of about 3 or less.7. A multi-part dental bleaching system as defined in claim 1, the dental bleaching having a pH of about 1-2.8. A multi-part dental bleaching system as defined in claim 1, at least one of the dental bleaching composition or the neutralizing composition further comprising at least one ion scavenger.9. A multi-part dental bleaching system as defined in claim 8, the ion scavenger comprising at least one of EDTA or citric acid.10. A multi-part dental bleaching system as defined in claim 1, the particulate base comprising at least one of an alkali metal oxide, an alkali metal hydroxide, an alkaline earth metal oxide, or an alkaline earth metal hydroxide.11. A multi-part dental bleaching system as defined in claim 1, the polymeric thickening agent comprising at least one of an acrylic acid polymer or carboxypolymethylene.12. A multi-part dental bleaching system as defined in claim 11, the at least one acrylic acid polymer comprising a cross-linked acrylic acid copolymer.13. A multi-part dental bleaching system as defined in claim 1, the polymeric thickening agent comprising at least one of a pluronic, a cellulosic ether, a polysaccharide gum, a protein or starch.14. A multi-part dental bleaching system as defined in claim 1, wherein the neutralizing composition further comprising a radiant energy absorbing agent.15. A multi-part dental bleaching system as defined in claim 14, the radiant energy absorbing agent comprising at least one dye.16. A multi-part dental bleaching system as defined in claim 1, at least one of the dental bleaching composition or neutralizing composition further comprising a polyol.17. A multi-part dental bleaching system as defined in claim 16, the polyol comprising at least one of glycerin, sorbitol, propylene glycol, polyethylene glycol, or polypropylene glycol.18. A multi-part dental bleaching system as defined in claim 1, at least one of the dental bleaching composition or neutralizing composition further comprising flumed silica.19. A multi-part dental bleaching system as defined in claim 1, the dental bleaching system being in the form of a kit that comprises the dental bleaching composition in a first part and the neutralizing composition in a second part.20. A multi-part dental bleaching system as defined in claim 19, the kit comprising at least one syringe containing the dental bleaching composition and at least one additional syringe containing the neutralizing composition.21. A multi-part dental bleaching system as defined in claim 19, the kit comprising at least one dual compartment syringe containing the dental bleaching composition in a first compartment and the neutralizing composition in a second compartment .22. A multi-part dental bleaching system as defined in claim 19, at least one of the dental bleaching composition or neutralizing composition being free of abrasives.23. A multi-part dental bleaching system as defined in claim 1, the neutralizing composition being a non-gelled mixture of dry solid components.24. A multi-part dental bleaching system comprising: an aqueous dental bleaching composition that comprises at least one dental bleaching agent and that has a pH of less than 4; and a substantially water free neutralizing composition suitable for mixing with the dental bleaching composition and that comprises at least one particulate base mixed with at least one thickening agent to form a mixture of dry solids. 25. A multi-part dental bleaching system comprising: an aqeous dental bleaching composition that includes at least about 30%, by weight of the system, of available hydrogen peroxide and that has an acidic pH; and a substantially water free neutralizing composition suitable for mixing with the dental bleaching composition comprising at least one particulate base mixed with at least one polymeric thickening agent to form a non-gelled mixture of dry solids. 26. A multi-part dental bleaching system as defined in claim 25, wherein the dental bleaching composition has a pH of less than about 3.27. A multi-part dental bleaching system as defined in claim 25, wherein the thickening agent comprises at least one of an acrylic acid polymer or carboxypolymethylene.28. A method of manufacturing a multi-part dental bleaching system comprising: (a) preparing a dental bleaching composition that comprises a dental bleaching agent and that has an acidic pH; and (b) preparing a neutralizing composition suitable for mixing with the dental bleaching composition by combining at least one alkaline base with at least one polymeric thickening agent yield a dry mixture of solids that is substantially water free and c) including said dental bleaching composition and said neutralizing composition in a multi-part dental bleaching system. 29. A method of manufacturing a multi-part dental bleaching system as defined in claim 28, the alkaline base comprising at least one of an alkali metal oxide, an alkali metal hydroxide, an alkaline earth metal oxide, ammonium hydroxide, or an alkaline earth metal hydroxide.30. A method of manufacturing a multi-part dental bleaching system as defined in claim 28, the polymeric thickening agent comprising at least one of an acrylic acid polymer or carboxypolymethylene.31. A method of bleaching a person's teeth comprising: (1) providing a multi-part dental bleaching system comprising: a dental bleaching composition that comprises a dental bleaching agent and that has a pH of less than 4; anda substantially water free neutralizing composition suitable for mixing with the dental bleaching composition and that comprises at least one particulate based mixed with at least one polymeric thickening agent; (2) mixing together the dental bleaching composition and the neutralizing composition to yield a mixed composition having a pH in a range of about 4 to about 11 and that comprises a sticky gel; and (3) applying the mixed composition comprising the sticky gel to at least a portion of the person's teeth.
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