초록 ▼

Disclosed is an improved electrode for use in an electrochemical sensor for measuring an analyte in a sample. The electrode includes a thin working layer whose thickness is from 2 to 10 microns. Also disclosed is an electrode strip that includes an electrode with a thin working layer. Typically, the

Disclosed is an improved electrode for use in an electrochemical sensor for measuring an analyte in a sample. The electrode includes a thin working layer whose thickness is from 2 to 10 microns. Also disclosed is an electrode strip that includes an electrode with a thin working layer. Typically, the thin working layer includes an enzyme and a redox mediator. In an electrode for measuring glucose, the enzyme can be glucose oxidase and the redox mediator can be ferrocene.

대표청구항 ▼

1. A sensor for measuring glucose in a sample of blood, said sensor comprising an electrode arrangement, which comprises an electrode support having at least one printed track of electroconductive carbon ink, said at least two printed tracks defining the positions of at least two electrodes, one of

1. A sensor for measuring glucose in a sample of blood, said sensor comprising an electrode arrangement, which comprises an electrode support having at least one printed track of electroconductive carbon ink, said at least two printed tracks defining the positions of at least two electrodes, one of said at least two electrodes comprising a thin working layer, said thin working layer having a thickness in the range of 2 to 10 microns, said thin working layer comprising a printed ink, said ink comprising an enzyme and a redox mediator, the other of said at least two electrodes being a reference electrode, said sensor, in the presence of a sample of blood, having a response slope that remains substantially constant in said thickness range. 2. The sensor of claim 1, wherein said thin working layer has a thickness of 4 to 8 microns. 3. The sensor of claim 1, wherein said thin working layer further comprises a binder, a film former, and a filler. 4. The sensor of claim 1, wherein said enzyme uses glucose as a substrate for said enzyme. 5. The sensor of claim 4, wherein said enzyme is selected from the group consisting of glucose oxidase and glucose dehydrogenase. 6. The sensor of claim 1, wherein said redox mediator is selected from the group consisting of ferrocene, a ferrocene derivative, ferricyanide, and an osmium complex. 7. The sensor of claim 1, wherein said thin working layer is a screen printed layer. 8. The sensor of claim 1, wherein said electrode arrangement comprises a working electrode, a dummy electrode, and a reference electrode. 9. The sensor of claim 8, said reference electrode is downstream of said working electrode, relative to direction of sample flow. 10. The sensor of claim 1, further comprising a hydrophilic mesh layer overlaying a sample loading area and said electrode arrangement. 11. The sensor of claim 10, further comprising a cover layer defining an upper boundary of a cell volume encompassing said electrode arrangement, and an aperture in said cover layer, said aperture located above said sample loading area. 12. The sensor of claim 1, wherein said printed track is overlaid by a track comprising a mixture of particles of silver and silver chloride.