Medical devices having full or partial polymer coatings and their methods of manufacture
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/00
A61M-025/00
출원번호
US-0177651
(2002-06-20)
발명자
/ 주소
Cox, Brian J.
출원인 / 주소
MicroVention, Inc.
대리인 / 주소
Buyan Robert D.
인용정보
피인용 횟수 :
56인용 특허 :
40
초록▼
Medical devices for insertion into the body of human or veterinary patients, wherein the device comprises a) a working element (e.g. a wire, a guidewire, a tube, a catheter, a cannula, a scope (e.g., rigid or flexible endoscope, laparoscope, sigmoidoscope, cystoscope, etc.) a probe, an apparatus for
Medical devices for insertion into the body of human or veterinary patients, wherein the device comprises a) a working element (e.g. a wire, a guidewire, a tube, a catheter, a cannula, a scope (e.g., rigid or flexible endoscope, laparoscope, sigmoidoscope, cystoscope, etc.) a probe, an apparatus for collecting information from a location within the body (e.g., an electrode, sensor, camera, scope, sample withdrawal apparatus, biopsy or tissue sampling device, etc.) which has an outer surface and b) a continuous or non-continuous coating on the outer surface of the working element. The outer surface of the working element is prepared to create a surface topography which promotes mechanical or frictional engagement of the coating to the working element. In some embodiments the coating is a lubricious coating and/or a swellable coating.
대표청구항▼
1. A medical device that is insertable into the body of a human or veterinary patient, said device comprising:a working element having an outer surface;a lubricious polymer coating disposed on at least a portion of the outer surface of the working element;the outer surface of said working element ha
1. A medical device that is insertable into the body of a human or veterinary patient, said device comprising:a working element having an outer surface;a lubricious polymer coating disposed on at least a portion of the outer surface of the working element;the outer surface of said working element having cavities formed therein, at least some of said cavities having side walls which are disposed at angles of about 75 or more degrees relative to the outer surface of the working element immediately adjacent to side walls; and,at least a portion of said lubricious polymer coating extending into said cavities so as to deter separation of the polymer coating from the working element. 2. A device according to claim 1 wherein the working element comprises a catheter or cannula. 3. A device according to claim 1 wherein the working element comprises a guidewire. 4. A device according to claim 1 wherein the working element comprises a scope. 5. A device according to claim 1 wherein the working element comprises an apparatus for obtaining information from a location within the patient's body. 6. A device according to claim 1 wherein the polymer coating becomes lubricious upon contact with a liquid. 7. A device according to claim 1 wherein the polymer coating comprises a hydrogel. 8. A device according to claim 1 wherein the polymer coating comprises a porous hydrogel. 9. A device according to claim 1 wherein the polymer coating expands in the presence of liquid. 10. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise pores. 11. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise grooves. 12. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise depressions. 13. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise indentations. 14. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise holes. 15. A device according to claim 1 wherein the cavities formed in the outer surface of the working element comprise slots. 16. A device according to claim 1 wherein the cavities formed in the outer surface of the working element extend only partially into the working element. 17. A device according to claim 1 wherein the cavities formed in the outer surface of the working element extend through the working element. 18. A device according to claim 1 wherein the porosity of the polymer coating is at least about 50%. 19. A device according to claim 1 wherein the polymer coating extends into cavities at least 0.001 inch below the outer surface. 20. A device according to claim 1 wherein the polymer coating extends into cavities such that the polymer coating extends to a depth below the outer surface that is at least about 25% of the total thickness of the polymer coating at that location. 21. A device according to claim 20 wherein the porosity of the polymer coating, when substantially fully expanded, is between about 50% and about 95%. 22. A device according to claim 1 where in substantially all of the polymer coating is initially contained within the cavities and such polymer coating subsequently expands such that a portion of said polymer coating protrudes out of the cavities. 23. A device according to claim 1 wherein substantially all of the polymer coating is initially contained within the cavities beneath the outer surface and such polymer coating subsequently expands such that a portion of said polymer coating protrudes out of the cavities and above the outer surface. 24. A device according to claim 1 wherein the polymer coating comprises a fluorocarbon. 25. A device according to claim 1 wherein the polymer coating comprises polytetrafluoroethylene. 26. A device according to claim 1 wherein the angle is at least 90 degrees. 27. A device according to claim 1 wherein the angle is greater than 90 degrees thereby creating an undercut surface. 28. A device according to claim 1 wherein the polymer coating expands when in contact with a liquid. 29. A device according to claim 1 wherein the polymer coating comprises a hydrogel that expands when in contact with a liquid. 30. A medical device that is insertable into the body of a human or veterinary patient, said device comprising:a working element having an outer surface;a polymer coating that expands when in contact with a liquid, said polymer coating being disposed on at least a portion of the outer surface of the working element;the outer surface of said working element having cavities formed therein, at least some of said cavities having side walls which are disposed at angles of about 75 or more degrees relative to the outer surface of the working element immediately adjacent to side walls; and,at least a portion of said polymer coating extending into said cavities so as to deter separation of the polymer coating from the working element. 31. A device according to claim 30 wherein the working element comprises a catheter or cannula. 32. A device according to claim 30 wherein the working element comprises a guidewire. 33. A device according to claim 30 wherein the working element comprises a scope. 34. A device according to claim 30 wherein the working element comprises an apparatus for obtaining information from a location within the patient's body. 35. A device according to claim 30 wherein the polymer coating is lubricious. 36. A device according to claim 30 wherein the polymer coating becomes lubricious upon contact with a liquid. 37. A device according to claim 30 wherein the polymer coating comprises a hydrogel. 38. A device according to claim 30 wherein the polymer coating comprises a porous hydrogel. 39. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise pores. 40. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise grooves. 41. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise depressions. 42. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise indentations. 43. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise holes. 44. A device according to claim 30 wherein the cavities formed in the outer surface of the working element comprise slots. 45. A device according to claim 30 wherein the cavities formed in the outer surface of the working element extend only partially into the working element. 46. A device according to claim 30 wherein the cavities formed in the outer surface of the working element extend through the working element. 47. A device according to claim 30 wherein the porosity of the polymer coating is at least about 50%. 48. A device according to claim 30 wherein the polymer coating extends into cavities at least 0.001 inch below the outer surface. 49. A device according to claim 30 wherein the polymer coating extends into cavities such that the polymer coating extends to a depth below the outer surface that is at least about 25% of the total thickness of the polymer coating at that location. 50. A device according to claim 30 wherein the porosity of the polymer coating, when substantially fully expanded, is between about 50% and about 95%. 51. A device according to claim 30 wherein substantially all of the polymer coating is initially contained within the cavities and such polymer coating subsequently expands such that a portion of said polymer coating protrudes out of the cavities. 52. A device according to claim 30 wherein substantially all of the polymer coating is initially contained within the cavities beneath the outer surface and such polymer coating subsequently expands such that a portion of said polymer coating pr otrudes out of the cavities and above the outer surface. 53. A device according to claim 30 wherein the polymer coating comprises a fluorocarbon. 54. A device according to claim 30 wherein the polymer coating comprises polytetrafluoroethylene. 55. A device according to claim 30 wherein the angle is at least 90 degrees. 56. A device according to claim 30 wherein the angle is greater than 90 degrees thereby creating an undercut surface. 57. A device according to claim 30 wherein the polymer coating comprises a hydrogel.
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