IPC분류정보
| 국가/구분 |
United States(US) Patent
등록
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| 국제특허분류(IPC7판) |
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| 출원번호 |
US-0756130
(2001-01-09)
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발명자
/ 주소 |
- Harth, Yoram
- Korman, Avner
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| 출원인 / 주소 |
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| 인용정보 |
피인용 횟수 :
37 인용 특허 :
24 |
초록
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An apparatus and method for the phototherapy of different skin conditions, particularly acne vulgaris and seborrhea. The invention consists of a combined treatment with violet/blue light source with a spectral emission in the range of 405-440 nanometer and possible additional spectral bands in the g
An apparatus and method for the phototherapy of different skin conditions, particularly acne vulgaris and seborrhea. The invention consists of a combined treatment with violet/blue light source with a spectral emission in the range of 405-440 nanometer and possible additional spectral bands in the green and red part of the spectrum and the topical application of oxygen transporting compounds, and/or a methylene blue solution. The apparatus includes at least one narrow spectral band light source with spectral emittance concentrated in the violet/blue spectral band and an optical system for controlling spectra and beam parameters of said light source and a mechanical fixture for holding the said light source at an adjustable distance and direction related to the skin treated area, and an electronic unit to control the duration and power and spectral bands of the emitted radiation.
대표청구항
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1. Apparatus for the treatment of a treatment area exhibiting a skin disorder and associated inflammation lying at or near the surface of the skin of a patient comprising:(a) a self supporting mechanical fixture for holding at least one light source in a fixed position spaced apart from the treatmen
1. Apparatus for the treatment of a treatment area exhibiting a skin disorder and associated inflammation lying at or near the surface of the skin of a patient comprising:(a) a self supporting mechanical fixture for holding at least one light source in a fixed position spaced apart from the treatment area during treatment thereof, said mechanical fixture comprising securing means for operatively securing the light source to the fixture and adjustment means for adjusting the distance or position of the light source from the treatment area;(b) at least one light source for emitting light with a peak spectral emittance concentrated in at least one narrow spectral band with the peak spectral emittance in one of said narrow spectral bands being in the range of 405 to 440 nm with an illumination power at the treatment area of 10 to 500 mw/cm 2 , said securing means of the mechanical fixture securing the light source in said fixed position when the light source is emitting the light;(c) an optical system for collecting and shaping the spectral emittance in advance of delivering the spectral emittance to the treatment area; and(d) electronic means for controlling parameters associated with the spectral emittance. 2. The apparatus of claim 1 comprising an illumination head comprising at least two converging collimated beams from at least two directions, each of said beams generated by a separate light source positioned at a distance from said other at least one light source. 3. The apparatus of claim 1 wherein the at least one light source is an ion krypton gas laser light source. 4. The apparatus of claim 1 wherein the system for shaping and collecting the spectral emittance is an optical system comprising two orthogonal cylindrical lenses. 5. The apparatus of claim 1 wherein each of the spectral bands is a narrow spectral band. 6. The apparatus of claim 1 further comprising cooling means for removing excess heat from the treatment area of the skin disorder. 7. The apparatus of claim 1 wherein the spectral emittance means comprises means for delivering a dose of at least 18 Joules/cm 2 . 8. The apparatus of claim 1 wherein the spectral emittance means comprises means for delivering a dose of at least 36 Joules/cm 2 . 9. The apparatus of claim 1 wherein the light source emits UV radiation, said apparatus further comprising filtering means for removing at least substantially all of the UV radiation emitted by the light source. 10. The apparatus of claim 1 wherein said light source delivers a principal skin disorder treating effective spectral emittance of light energy range in the range of 405 to 450 nm. 11. The apparatus of claim 1, wherein said parameters are selected from the group consisting of duration, radiated power and emitted spectral bands of said spectral emittance. 12. The apparatus of claim 1 wherein the treatment area is the head of a patient including a face and a chin, said light source comprising means for delivering the spectral emittance of energy to the face, the chin or combination thereof. 13. The apparatus of claim 1, wherein said spectral emittance has a power density of at least 20 mW/cm 2 . 14. The apparatus of claim 1 wherein said spectral emittance has a power density of at least 40 mW/cm 2 . 15. The apparatus of claim 1 comprising means for delivering the spectral emittance for a minimum treatment time of 15 minutes. 16. The apparatus of claim 15 comprising means for delivering the spectral emittance for a treatment time of from 15 to 60 minutes. 17. The apparatus of claim 1 wherein the adjustment means adjusts the distance or position of the light source to enable treatment of a treatment area of at least 200 cm 2 . 18. The apparatus of claim 1, wherein the optical system further comprises:at least one optical element selected from the group consisting of a liquid filled light guide, a solid transparent light guide, a fiber bundle light guide and an array of lenses and mirrors for collecting and shap ing said spectral emittance and for illuminating a treatment area at an adjustable distance, energy density and direction. 19. The apparatus of claim 1, wherein said at least one light source is a gas discharge lamp. 20. The apparatus of claim 1, wherein said at least one light source comprises at least one material selected from the group consisting of Gallium, Mercury and metal halides in the form of a gas mixture discharge lamp. 21. The apparatus of claim 1, wherein said at least one light source further comprises at least one reflector for collecting and projecting the spectral emittance toward the skin disorder. 22. The apparatus of claim 21 wherein said reflector is selected from the group comprising of an elliptical cross-section cylindrical reflector, a parabolic cross-section cylindrical reflector, and an asymmetric aspheric reflector. 23. The apparatus of claim 1, wherein the electronic means for controlling parameters associated with the spectral emittance comprises an integrated computer module. 24. The apparatus of claim 1, wherein said at least one light source is at least one diode selected from the group consisting of violet/blue laser diodes and light emitting diodes (LED), and combinations thereof with a narrow spectral band emission in the range 405-440 nm. 25. The apparatus of claim 1, wherein said at least one light source is an array of diodes selected from the group consisting of violet/blue light emitting diodes (LED) and laser diodes, and red and green light emitting diodes (LED) and laser diodes. 26. The apparatus of claim 1, wherein said at least one light source is selected from the group consisting of LED diodes, laser diodes and gas discharge lamps and combinations thereof. 27. The apparatus of claim 1, wherein the spectral emittance of at least one spectral band is in the green and red range. 28. The apparatus of claim 1 wherein the skin disorder is selected from the group consisting of acne and seborrhea. 29. A method of treating a treatment area exhibiting a skin disorder and associated inflammation at or near the surface of the skin of a patient comprising:(a) positioning in an operative treating position for treating a skin disorder a self supporting mechanical fixture comprising at least one light source in a fixed position spaced apart from the treatment area, said mechanical fixture comprising securing means for operatively securing the light source to the fixture, and adjustment means for adjusting the distance or position of the light source from the treatment area; and(b) applying to the treatment area in a plurality of discontinuous applications a peak spectral emittance of light energy at least in the substantial absence of UV radiation sufficient to effectively treat the skin disorder, said peak spectral emittance concentrated in at least one narrow spectral band with the peak spectral emittance of one of said narrow spectral bands being in the range of 405 to 440 nm with an illumination power at the treatment area of 10 to 500 mw/cm 2 while maintaining the treatment area at a patient acceptable temperature. 30. The method of claim 29 wherein the skin disorder is caused by skin disorder generating bacteria, said method comprising applying said spectral emittance of light energy for a time sufficient to facilitate the reaction of porphoryins produced by the bacteria and oxygen to produce peroxides which are toxic to the bacteria. 31. The method of claim 29 comprising applying said spectral emittance of light energy at time periods which enable the porphoryins produced by the bacteria during the time period between each application to react with oxygen in the presence of said spectral emittance and consequently to produce peroxides and for the peroxides to kill the bacteria in sufficient amounts so as to reduce the mass of bacteria associated with the skin disorder, and repeating the application until the bacteria mass is reduced below a predetermined level. 32. The method of claim 29 further comprising removing heat from the skin to maintain the skin at a patient acceptable temperature. 33. The method of claim 29 comprising applying to the treatment area a spectral emittance of light energy which has had UV radiation filtered therefrom. 34. The method of claim 29 wherein each discontinuous application is at least 15 minutes. 35. The method of claim 29 wherein each discontinuous application is from 15 to 60 minutes. 36. The method of claim 29 wherein the treatment area of the skin disorder is at least 200 cm 2 . 37. The method of claim 29 comprising controlling parameters associated with the spectral emittance of light energy through an integrated computer module. 38. The method of claim 37 wherein the integrated computer module comprises a display unit for displaying an imaged illumination treatment area. 39. The method of claim 38 wherein the integrated computer module comprises a display unit comprising a touch screen. 40. The method of claim 29, wherein the spectral emittance of light energy is from at least one diode selected from the group consisting of violet/blue laser diodes and light emitting diodes (LED), and combinations thereof with narrow spectral band emission in the range 405-440 nm. 41. The method of claim 29, wherein the spectral emittance of light energy is from an array of diodes selected from the group consisting of violet/blue light emitting diodes (LED) and laser diodes, and light emitting diodes (LED) and laser diodes with spectral bands emission in the red and green range. 42. The method of claim 29, wherein the spectral emittance of light energy is from a member selected from the group consisting of LED diodes, laser diodes and gas discharge lamps and combinations thereof. 43. The method of claim 29, wherein the spectral bands of the spectral emittance are in the violet/blue range and at least one spectral band in the green and red range. 44. The method of claim 29 wherein the skin disorder is selected from the group consisting of acne and seborrhea.
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