Medical device including unitary, continuous portion of varying durometer
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-025/00
B29C-045/00
B29C-047/00
B29D-009/00
출원번호
US-0848742
(2001-05-03)
발명자
/ 주소
Boatman, Scott E.
Burton, David G.
Hoffa, Michael C.
Osborne, Thomas A.
Drewes, Jr., David A.
Lessard, David R.
Hupcey, Maggie A. Z.
출원인 / 주소
Cook Incorporated
대리인 / 주소
Brinks Hofer Gilson &
인용정보
피인용 횟수 :
12인용 특허 :
129
초록▼
A medical device (110) including a catheter shaft (111) and a unitarily and continuously formed portion (108) having a varying durometer, and optionally including an expandable balloon (18, 118). One or both of the unitarily and continuously formed portion (108) and the balloon (18, 118) are made fr
A medical device (110) including a catheter shaft (111) and a unitarily and continuously formed portion (108) having a varying durometer, and optionally including an expandable balloon (18, 118). One or both of the unitarily and continuously formed portion (108) and the balloon (18, 118) are made from an irradiation cross-linked or cross-linkable mixture of a polyamide elastomer and at least one additional cross-linking reactant. The polyamide elastomer can be a polyester amide, a polyether ester amide or a polyether amide, and is preferably a nylon block copolymer. The aromatic molecule can be 1,3,5 triethyl benzene; 1,2,4 triethyl benzene; and 1,3,5 triisopropyl benzene. The cross-linking reactant can be: (a) a difunctional material, (b) a trifunctional material, (c) a tetrafunctional material, or (d) an aromatic molecule containing at least two ring substituents, each of the ring substituents having labile hydrogens at a benzylic site therein. The cross-linking reactant can also be diallyl phthalate or meta-phenylene dimaleimide.
대표청구항▼
1. A medical device (110) comprising a unitarily and continuously formed portion (108) having a varying durometer wherein the unitarily and continuously formed portion (108) comprises an irradiation cross-linkable mixture of a polyamide elastomer and at least one additional cross-linking reactant, t
1. A medical device (110) comprising a unitarily and continuously formed portion (108) having a varying durometer wherein the unitarily and continuously formed portion (108) comprises an irradiation cross-linkable mixture of a polyamide elastomer and at least one additional cross-linking reactant, the at least one cross-linking reactant comprising diallyl phthalate or meta-phenylene dimaleimide, and the mixture comprising about 1 to about 2 percent by weight of the at least one cross-linking reactant.2. A medical device (110) comprising:a unitarily and continuously formed portion (108) having a varying durometer, the unitarily and continuously formed portion (108) including an irraciation cross-linkable mixture of a polyamide elastomer and at least one additional or cross-linking reactant, the cross-linking reactant selected from the group consisting of (a) a difunctional material selected from the class consisting of diallyl adipate; diallyl carbonate; diallyl maleate; diallyl succinate; diallyl tetrabromophthalate; diethyl diallylmalonate; dimethyl diallylmalonate; and 2,2,6,6tetra-bromobisphenol A diallyl ether; (b) a trifunctional material selected from the class consisting of 2,5-diallyl-4, 5-dimethyl-2-cyclopenten-1-one; diallyl fumarate; diallyl itaconate; 1,3,5-triallyl-2 methuoxybenzene; triallyl trimesate (triallyl 1,3,5-benzenetricarboxylate); triallyl trimellitate (triallyl 1,2,4-benzenetricarboxylate); and pentaerythrizol triallyl ether; (c) a tetrafunctional material selected from the class consisting of tetraallyl cis,cis,cis,cis-cyclopentane-1,2,3,4-tetracarboxylate; and N,N,N′,N′-tetraallylethytenediamine; and (d) an aromatic molecule containing at least two ring substituents, each of the ring substituents having labile hydrogens at a benzylic site therein; and wherein the unitarily and continuously formed portion (108) comprises at least first and second parts (102 and 104) unitarily and continuously formed with one another, at least one of the first and second parts (102 or 104) being exposed to cross-linking irradiation, wherein the mixture comprises an irradiation cross-linkable mixture of a polyamide elastomer and an aromatic molecule containing at least two ring substituents, each of the ring substituents having labile hydrogens at a benzylic site therein, selected from the class consisting of 1,3,5 triethyl benzene; 1,2,4 triethyl benzene; and 1,3,5 triisopropyl benzene. 3. A medical device (110) comprising:a unitarily and continuously formed portion (108) having a varying durometer and including an irradiation cross-linkable mixture of a polyamide elastomer and at least one additional cross-linking reactant, the cross-linking reactant selected from the group consisting of: (a) a difunctional material selected from the class consisting of diallyl adipate; diallyl carbonate; diallyl maleate; diallyl succinate; diallyl tetrabromophthalate; diethyl diallylmalonate; dimethyl diallylmalonate; and 2,2,6,6 tetra-bromobisphenol A diallyl ether; (b) a trifunctional material selected from the class consisting of 2,5-diallyl-4,5-dimethyl-2-cyclopenten-1-one; diallyl fumarate; diallyl itaconate1,3,5-triallyl-2 methoxybenzene; triallyl trimesate (triallyl 1,3,5-benzenetricarboxylate); triallyl trimellitate (triallyl 1,2,4-benzanetricarboxylate); and pentaerythritol triallyl ether; (c) a tetrafunctional material selected from the class consisting of tetraallyl cis,cis,cis,cis-cyclopentane-1,2,3,4-tetracarboxylate; and N,N,N′,N′-tetraallylethylenediamine; and (d) an aromatic molecule containing at least two ring substituents, each of the ring substituents having labile hydrogens at a benzylic site therein, wherein the unitarily and continuously formed portion (103) comprises at least first and second parts (102 and 104) unitarily and continuously formed with one another, at least one of the first and second parts (102 or 104) being exposed to cross-linking irradiation. 4. The medical device (110) according to claim 3, wherein the unitarily and continuously formed portion (108) comprises a tubular portion (106).5. The medical device (110) according to claim 4, wherein the tubular portion (106) comprises a catheter shaft (111).6. The medical device (110) according to claim 3, wherein the first and second unitarily and continuously formed parts (102 and 104) of the unitarily and continuously formed portion (108) are exposed to different amounts of cross-linking irradiation.7. The medical device (110) according to claim 3, wherein the mixture comprises one of the following ranges: about 1 to about 3 percent by weight of the difunctional material; about 0.5 to about 1.5 percent by weight of the trifunctional material; 0.5 to about 1.5 percent by weight of the aromatic molecule and about 0.01 to about 1 percent by weight of the tetrafunctional material.8. The medical device (110) according to claim 3, wherein the unitarily and continuously formed portion (108) comprises an amount of the at least one cross-linking reactant sufficient to give the unitarily and continuously formed portion (108) a strength generally about equal to that of a unitarily and continuously formed portion (108) composed of the polyamide elastomer and comparably cross-linked by irradiation, but in the absence of any cross-linking reactant, agent or promoter.9. The medical device (110) according to claim 3, wherein the at least one cross-linking reactant which has been cross-linked, at least in part, by irradiation with an electron beam or with ultraviolet, X- or gamma rays.10. The medical device (110) according to claim 3, wherein the at least one cross-linking reactant which has been cross-linked, at least in part, by exposure to about 0.5 about 60 megarads of radiation.11. The medical device (110) according to claim 3, wherein the mixture comprises at least one polyamide elastomer selected from the class consisting of polyester amides, polyether ester amides and polyether amides.12. The medical device (110) according to claim 11, wherein the mixture comprises a nylon block copolymer.13. The medical device (110) according to claim 12, wherein the mixture comprises a nylon block copolymer including polyether blocks separated by polyamide blocks.14. The medical device (110) according to claim 3, wherein the unitarily and continuously formed portion (108) comprises about 0.5 percent to about 5 percent by weight of at least one additional cross-linking reactant, the cross-linking reactant comprising triallyl cyanurate or triallyl isocyanurate.15. The medical device (110) according to claim 3, wherein the mixture comprises: a nylon block copolymer including polyether blocks separated by polyamide blocks, about 3 percent by weight triallyl isocyanurate and about 10 percent by weight nylon.
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이 특허에 인용된 특허 (129)
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