IPC분류정보
국가/구분 |
United States(US) Patent
등록
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국제특허분류(IPC7판) |
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출원번호 |
US-0357647
(1999-07-20)
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발명자
/ 주소 |
- Bouchard, Clement D.
- Gray, Lawrence B.
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출원인 / 주소 |
- Deka Products Limited Partnership
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대리인 / 주소 |
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인용정보 |
피인용 횟수 :
143 인용 특허 :
37 |
초록
▼
The present invention involves, in some embodiments, reusable pump drive systems, which are coupled to removable, and preferably disposable, pumping cartridges. The invention provides, in some embodiments, novel pumping cartridges for use in pumping systems. One such cartridge includes an integrated
The present invention involves, in some embodiments, reusable pump drive systems, which are coupled to removable, and preferably disposable, pumping cartridges. The invention provides, in some embodiments, novel pumping cartridges for use in pumping systems. One such cartridge includes an integrated filter element therein for filtering fluids, for example fluids pumped to the body of a patient in a medical procedure. In some embodiments, the integrated filter is utilized as a blood clot removal filter and in other embodiments is used to remove particulates liquids infused to a patient. The filter element includes a filter with pores therein that are preferably sized to permit essentially unrestricted flow of individual human blood cells therethrough and to block or collect blood clots, cell clumps, particulates etc. with sizes substantially larger than the average size of a human blood cell.
대표청구항
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1. A removable pumping cartridge constructed and arranged for operative association with a reusable component, the cartridge comprising:at least one pump chamber; one or more valving chambers; a substantially rigid first component and one or more flexible membranes disposed on the first component, t
1. A removable pumping cartridge constructed and arranged for operative association with a reusable component, the cartridge comprising:at least one pump chamber; one or more valving chambers; a substantially rigid first component and one or more flexible membranes disposed on the first component, the first component and the one or more flexible membranes defining at least a portion of the pump chamber and a portion of the valving chamber; at least one fluid flow path constructed and positioned within said cartridge to provide fluid communication between said pump chamber and a body of a patient when pumping a fluid thereto; and at least one filter element in fluid communication with the fluid flow path, wherein at least one of said one or more valving chambers comprises a bypass valving chamber, said bypass valving chamber having at least one port therein in fluid communication with the filter element. 2. The removable pumping cartridge of claim 1, wherein the pumping cartridge is disposable and designed for a single use.3. The removable pumping cartridge of claim 1, wherein the filter element includes a substantially planar filter, said filter being essentially co-planar to a region of the first component of the pumping cartridge to which the filter is attached.4. The removable pumping cartridge of claim 1, wherein the filter element includes an inlet port in fluid communication with a first side of the filter element and an outlet port in fluid communication with a second side of the filter element.5. A removable pumping cartridge constructed and arranged for operative association with a reusable component, the cartridge comprising:at least one pump chamber; at least one valving chamber; a substantially rigid first component and one or more flexible membranes disposed on the first component, the first component and the one or more flexible membranes defining at least a portion of the pump chamber and a portion of the valving chamber; at least one fluid flow path constructed and positioned within said cartridge to provide fluid communication between said pump chamber and a body of a patient when pumping a fluid thereto; and at least one filter element in fluid communication with the fluid flow path, wherein the filter element includes a substantially planar filter, said filter being essentially co-planar to a region of the first component of the pumping cartridge to which the filter is attached, and wherein the substantially planar filter comprises a screen, said screen sized to allow passage of human blood cells through the screen. 6. The removable pumping cartridge of claim 5, wherein the pumping cartridge is disposable and designed for a single use.7. The removable pumping cartridge of claim 5, wherein the filter element includes an inlet port in fluid communication with a first side of the filter element and an outlet port in fluid communication with a second side of the filter element.8. A removable pumping cartridge constructed and arranged for operative association with a reusable component, the cartridge comprising:at least one pump chamber; at least one valving chamber; a substantially rigid first component and one or more flexible membranes disposed on the first component, the first component and the one or more flexible membranes defining at least a portion of the pump chamber and a portion of the valving chamber; at least one fluid flow path constructed and positioned within said cartridge to provide fluid communication between said pump chamber and a body of a patient when pumping a fluid thereto; and at least one filter element in fluid communication with the fluid flow path, wherein the filter element includes an inlet port in fluid communication with a first side of the filter element and an outlet port in fluid communication with a second side of the filter element, and wherein the filter element, when in operative association with the reusable component, is positioned in a substantially vertical orientation with the outlet port located below the inlet port so that any air present within the filter element is inhibited from exiting the filter element through the outlet port, when the pumping cartridge is in operation, and wherein the filter element includes a substantially planar filter, said filter being essentially co-planar to a region of the first component of the pumping cartridge to which the filter is attached. 9. A method of filtering a liquid supplied to the vasculature of a patient comprising:supplying a liquid to a pump chamber disposed in a removable pumping cartridge, which pumping cartridge is constructed and arranged for operative association with a reusable component, the pumping cartridge further including at least one filter element disposed therein and being comprised of a substantially rigid first component and at least one liquid impermeable membrane disposed on the first component, the first component and the membrane together at least partially forming both the pump chamber and the filter element; and pumping said liquid to the patient through the filter element disposed in the pumping cartridge, wherein the pumping step comprises passing the liquid through a bypass valving chamber in fluid communication with an outlet port of the filter element. 10. The method of claim 9, further comprising coupling the pumping cartridge in operative association with the reusable component.11. The method of claim 10, wherein the pumping step includes:pumping the liquid through an inlet port in fluid communication with a first side of the filter element; passing the liquid through a filter to a second side of the filter element; and flowing the liquid through an outlet port in fluid communication with the second side of the filter element, said outlet port being located below the inlet port when the pumping cartridge is coupled to the reusable component such that any air present in the pumped liquid collects within the filter element and is inhibited from exiting the filter element through the outlet port. 12. A method of filtering a liquid supplied to the vasculature of a patient comprising:supplying a liquid to a pump chamber disposed in a removable pumping cartridge, which pumping cartridge is constructed and arranged for operative association with a reusable component, the pumping cartridge further including disposed therein at least one chamber defining a filter element comprising a filter, the cartridge being comprised of a substantially rigid first component and at least one liquid impermeable membrane disposed on the first component, the first component and the membrane together at least partially forming both the pump chamber and the chamber defining the filter element, wherein the chamber defining the filter element has a thickness, as measured in a direction essentially perpendicular to a portion of a surface of the impermeable membrane that at least partially forms the chamber defining the filter element, which is smaller than each of a height and a width of the chamber defining the filter element; pumping said liquid to the patient through the filter element disposed in the pumping cartridge; and disposing the pumping cartridge after a single use. 13. The method of claim 12, further comprising coupling the pumping cartridge in operative association with the reusable component.14. The method of claim 13, wherein the pumping step includes:pumping the liquid through an inlet port in fluid communication with a first side of the filter element; passing the liquid through a filter to a second side of the filter element; and flowing the liquid through an outlet port in fluid communication with the second side of the filter element, said outlet port being located below the inlet port when the pumping cartridge is coupled to the reusable component such that any air present in the pumped liquid collects within the filter element and is inhibited from exiting the filter element through the outlet port. 15. A method of filtering a liquid supplied to the vasculature of a patient comprising:supplying a liquid to a pump chamber disposed in a removable pumping cartridge, which pumping cartridge is constructed and arranged for operative association with a reusable component, the pumping cartridge further including disposed therein at least one chamber defining a filter element comprising a filter, the cartridge being comprised of a substantially rigid first component and at least one liquid impermeable membrane disposed on the first component, the first component and the membrane together at least partially forming both the pump chamber and the chamber defining the filter element, wherein the chamber defining the filter element has a thickness, as measured in a direction essentially perpendicular to a portion of a surface of the impermeable membrane that at least partially forms the chamber defining the filter element, which is smaller than each of a height and a width of the chamber defining the filter element; and pumping said liquid to the patient through the filter element disposed in the pumping cartridge; wherein the liquid pumped to the patient is at least one of blood and a suspension of human blood cells and wherein during the pumping step, a substantial fraction of clotted blood or aggregated blood cells are removed from the liquid by the filter element. 16. The method of claim 15, further comprising coupling the pumping cartridge in operative association with the reusable component.17. The method of claim 16, wherein the pumping step includes:pumping the liquid through an inlet port in fluid communication with a first side of the filter element; passing the liquid through a filter to a second side of the filter element; and flowing the liquid through an outlet port in fluid communication with the second side of the filter element, said outlet port being located below the inlet port when the pumping cartridge is coupled to the reusable component such that any air present in the pumped liquid collects within the filter element and is inhibited from exiting the filter element through the outlet port. 18. A removable pumping cartridge constructed and arranged for operative association with a reusable component, the cartridge comprising:a substantially rigid first component including a surface having therein at least a first depression, a second depression, and a third depression; a flexible membrane disposed on the first component, the first depression and the flexible membrane together defining a pump chamber, the second depression and the flexible membrane together defining a valving chamber, and the third depression and the flexible membrane together defining a chamber including at least one filter therein and at least one fluid flow path constructed and positioned to provide fluid communication between said chamber including at least one filter therein and either or both said pump chamber and said valving chamber.
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