[특허]Intravaginal devices containing progesterone for estrus synchronization and related proceses

[미국특허] Intravaginal devices containing progesterone for estrus synchronization and related proceses 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-006/06
출원번호	US-0922493 (2004-08-19)
우선권정보	AR-P010104978 (2001-10-24)
발명자 / 주소	Massara, Julio Eduardo Massara, Nestor Gerardo Dvoskin, Victor Oscar
출원인 / 주소	Akzo Nobel N.V.
인용정보	피인용 횟수 : 17 인용 특허 : 16

초록

Embodiments of the present invention generally relate to devices and processes related to estrus synchronization. Particular embodiments of devices and processes of the present invention slowly release progesterone over a period of time for estrus synchronization.

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1. An intravaginal device comprising:an intravaginal anchoring system comprising a middle portion, a first opposing portion, a second opposing portion, a first branch and a second branch wherein the first and second opposing portions extend from the middle portion and the first branch extending from the first opposing portion and the second branch extending from the second opposing portion; a chamber located within the middle portion; at least one hole in at least one of the first opposing portion, the second opposing portion, the first branch and/or the second branch; and, a free space located within the anchoring system and connected to the chamber and the at least one hole. 2. The device of claim 1 further comprising progesterone.3. The device of claim 1 further comprising at least one strip on at least one of the first and second opposing portions and/or the first and/or second branch.4. The device of claim 1 further comprising a thread attached about an end of the second portion.5. The device of claim 1 wherein the middle portion is an elongated tubular member.6. The device of claim 5 wherein the first and second opposing extend opposite from the ends of the middle portion.7. The device of claim 5 wherein an angle at the intersection of the first opposing portion and the first branch is about 90 degrees.8. The device of claim 1 further comprising a sheath.9. The device of claim 1 further comprising a hollow tube for loading the device into the vagina of an organism.10. The device of claim 1 further comprising a thread.11. The device of claim 1 wherein at least one branch or at least one portion is larger than the respective portion or branch.12. A process for the synchronization of an organisms estrus cycle comprising the steps of:inserting a device into a vaginal duct of an organism comprising the device of claim 1; leaving the device in the organism for between 1 and 100 days; and, removing the device. 13. The process of claim 12 further comprising attempting to artificially inseminate the organism after removing the device.14. The process of claim 13 further comprising the step of reusing the device if the organism was not inseminated.15. The process of claim 14 wherein the step of reusing the device further comprises sliding a sheath on the device.16. The process of claim 14 wherein the step of reusing the device further comprises the injecting a medicament in the device.17. The process of claim 12 wherein the device has a medicament.18. The process of claim 17 wherein the medicament is progesterone.19. The process of claim 12 wherein the device is left in the organism between 3 and 7 days.20. A process for the synchronization of an organisms estrus cycle comprising the steps of:inserting a medicament containing device, comprising an inner duct, an external surface, at least one hole, and at least one communicating hole, wherein the at least one hole connects the inner duct to the external surface, the inner duct extending to the at least one communicating hole, within the vaginal duct of an organism, whereby the device allows progesterone to flow along two alternate paths, from the inner duct to the exterior surface of the device and towards the internal surface of the inner duct, from which the medicament is able to flow through the communicating holes to the vaginal duct. 21. The process of claim 20 wherein the medicament is progesterone.22. The process of claim 20 wherein the medicament is contained within the device of claim 1.

이 특허에 인용된 특허 (16) 인용/피인용 타임라인 분석

Heller Jorge (Palo Alto CA) Baker Richard W. (Bend OR), Bioerodible system for delivering drug manufactured from poly(carboxylic acid).
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Higuchi Takeru (Lawrence KS) Hussain Anwar (Lexington KY), Device consisting of copolymer having acetoxy groups for delivering drugs.
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Michael John Rathbone NZ; Shane Burccraff NZ; James Frederick Pharaoh NZ, Intra-vaginal device for pigs.
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Zimerman Clota E. (9 de Julio 532-A Cordoba ARX), Intrauterine contraceptive device.
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Higuchi Takeru (Lawrence KS) Hussain Anwar A. (Lexington KY), Intrauterine system embracing selected copolymeric membranes for administering beneficial agent.
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Nash Harold A. (Harrington Park NJ) Mishell ; Jr. Daniel R. (Palos Verdes Estates CA), Intravaginal ring.
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Wong Patrick S.-L. (Palo Alto CA), Method for the management of hyperplasia.
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Millar Thomas D. (Hamilton NZX) Miller David M. (Hamilton NZX), Methods of making intra-vaginal devices and/or intra-vaginal devices.
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Leeper Harold M. (Mountain View CA) Michaels Alan S. (Atherton CA), Novel drug permeable wall.
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Higuchi Takeru (Lawrence KS) Leeper Harold M. (Mountain View CA), Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient.
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Davis Robert C. (Greenfield IN) Gibson John W. (Birmingham AL) Skinner ; Jr. Daniel S. (Fountaintown IN) Dearth Timothy E. (Indianapolis IN) Harris Dale C. (Fairland IN), Rumen delivery device.
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Michael John Rathbone NZ; Craig Robert Bunt NZ; Shane Burggraaf NZ, Synchronizing of animal oestrus and intra vaginal devices useful therein.
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Rathbone, Michael John; Bunt, Craig Robert; Burggaaf, Shane, Synchronizing of animal oestrus and intra vaginal devices useful therein.
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Pocknell David (Antibes FRX), Therapeutic rings.
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Wong Patrick S. (Hayward CA), Vaginal dispenser for dispensing beneficial hormone.
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Schopflin Gisela (Berlin DT) Laudahn Gerhard (Berlin DT) Muhe Barbara (Berlin DT) Hartmann Heidemarie (Berlin DT) Windt Fred (Berlin DT), Vaginal ring.
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이 특허를 인용한 특허 (17) 인용/피인용 타임라인 분석

Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Cacace, Janice Louise; Persicaner, Peter H. R.; Irani, Neda; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Persicaner, Peter H. R.; Amadio, Julia M., Natural combination hormone replacement formulations and therapies.
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Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Progesterone formulations.
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Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Irani, Neda; Cacace, Janice Louise; Thorsteinsson, Thorsteinn; Sancilio, Frederick D., Soluble estradiol capsule for vaginal insertion.
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Shadiack, Annette; Persicaner, Peter H. R.; Inskeep, Philip B.; Thorsteinsson, Thorsteinn; Sancilio, Frederick D.; Legassie, Jason D., Steroid hormone pharmaceutical composition.
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Brines,Michael L.; Cerami,Anthony; Wuerth,Jean Paul, Sustained release delivery systems for solutes.
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Bernick, Brian A.; Amadio, Julia M.; Persicaner, Peter H. R.; Cacace, Janice Louise; Irani, Neda; Sancilio, Frederick D., Transdermal hormone replacement therapies.
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Bernick, Brian A.; Amadio, Julia M., Vaginal inserted estradiol pharmaceutical compositions and methods.
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Mirkin, Sebastian; Amadio, Julia M.; Bernick, Brian A., Vaginal inserted estradiol pharmaceutical compositions and methods.
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[미국특허] Intravaginal devices containing progesterone for estrus synchronization and related proceses 원문보기

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[미국특허] Intravaginal devices containing progesterone for estrus synchronization and related proceses 원문보기

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이 특허에 인용된 특허 (16) 인용/피인용 타임라인 분석

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