Dental bleaching compositions and devices having a solid activation adhesive layer or region and bleaching gel layer or region
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61C-005/00
A61C-017/02
A61C-017/00
출원번호
US-0784063
(2004-02-19)
발명자
/ 주소
Allred,Peter M.
Fischer,Dan E.
출원인 / 주소
Ultradent Products, Inc.
대리인 / 주소
Workman Nydegger
인용정보
피인용 횟수 :
16인용 특허 :
66
초록▼
Dental bleaching compositions in the shape of a dental tray, strip or patch include an adhesive activation composition and a dental bleaching gel. A barrier layer may be included to form a dental bleaching device that protects the bleaching composition from saliva or moisture during use. The adhesiv
Dental bleaching compositions in the shape of a dental tray, strip or patch include an adhesive activation composition and a dental bleaching gel. A barrier layer may be included to form a dental bleaching device that protects the bleaching composition from saliva or moisture during use. The adhesive activation composition is substantially solid and has increased adhesiveness to oral tissue when moistened with saliva or water. The adhesive activation composition is formed from an intermediate composition that is heated to drive off the solvent. Using a bleaching gel separate from the adhesive activation composition improves the potency and stability of the bleaching agent prior to use. During use, saliva or moisture cause the bleaching gel to be activated as the bleaching agent activator in the activation composition is leached therefrom so as to react with and destabilize the bleaching agent within the bleaching gel.
대표청구항▼
What is claimed is: 1. In a dental treatment system that includes a moisture-resistant barrier layer adapted to be placed upon and worn over a treatment composition used in treating a person's teeth, an article of manufacture comprising: a substantial dry adhesive activation composition that is suf
What is claimed is: 1. In a dental treatment system that includes a moisture-resistant barrier layer adapted to be placed upon and worn over a treatment composition used in treating a person's teeth, an article of manufacture comprising: a substantial dry adhesive activation composition that is sufficiently solid so that it will substantially maintain either a tray-like or a strip-like configuration so as to be adapted for handling and application to a patient's teeth either with or independent of the barrier layer, and the adhesive activation composition having increased adhesiveness to teeth when moistened by saliva or water and, comprising at least one tooth adhesion agent that at least partially contributes to said increased adhesiveness to teeth and at least one bleaching agent activator; and a substantially viscous and tacky dental bleaching gel, adjacent to said adhesive activation composition, comprising at least one dental bleaching agent, at least one tackifying agent, and a liquid or gel carrier. 2. An article of manufacture as defined in claim 1, said adhesive activation composition having a tray-like configuration comprising a least two sidewalls that define a trough within which the dental bleaching gel resides prior to use. 3. An article of manufacture as defined in claim 2, said adhesive activation composition having a horse-shoe configuration so as to approximate the curvature of a person's dental arch. 4. An article of manufacture as defined in claim 2, said adhesive activation composition having a substantially straight longitudinal profile prior to use so that longitudinal curving is required when the article is placed over a person's teeth. 5. An article of manufacture as defined in claim 2, at least a portion of said trough having a cross section that is approximately U-shaped, V-shaped, L-shaped, rectangular, or trapezoidal. 6. An article of manufacture as defined in claim 1, said adhesive activation composition comprising a strip or patch prior to use. 7. An article of manufacture as defined in claim 1, wherein said adhesive activation composition is designed so as to approximately terminate at or near a person's gingival margin during use. 8. An article of manufacture as defined in claim 1, said tooth adhesion agent within said adhesive activation composition comprising at least one of polyvinyl pyrrolidone (PVP), carboxypolymethylene, polyethylene oxide, polyacrylic acid, copolymer of polyacrylic acid, polyacrylate, polyacrylamide, copolymer of polyacrylic acid and polyacrylamide, PVP-vinyl acetate copolymer, carboxymethylcellulose, carboxypropylcellulose, polysaccharide gum, or protein. 9. An article of manufacture as defined in claim 1, said bleaching agent activator comprising at least one of a base, a metal, a metal compound, or an enzyme. 10. An article of manufacture as defined in claim 1, said bleaching agent activator having a concentration in a range of about 0. 01% to about 20% by weight of said adhesive activation composition. 11. An article of manufacture as defined in claim 1, said adhesive activation composition further comprising at least one humectant. 12. An article of manufacture as defined in claim 1, wherein said adhesive activation composition has a cross-sectional thickness in a range of about 0.1 mm to about 0.5 mm. 13. An article of manufacture as defined in claim 1, wherein said adhesive activation composition has a cross-sectional thickness in a range of about 0.5 mm to about 2 mm. 14. An article of manufacture as defined in claim 1, wherein said adhesive activation composition has a cross-sectional thickness in a range of about 2 mm to about 3 mm. 15. An article of manufacture as defined in claim 1, said adhesive activation composition further comprising at least one member selected from the group comprising dental desensitizing agents, remineralizing agent, antimicrobial agents, antiplaque agents, and anti-tartar agents. 16. An article of manufacture as defined in claim 1, said dental bleaching gel being substantially anhydrous prior to use. 17. An article of manufacture as defined in claim 1, said dental bleaching gel further comprising at least one member selected from the group comprising dental desensitizing agents, remineralizing agent, antimicrobial agents, antiplaque agents, and anti-tartar agents. 18. An article of manufacture as defined in claim 1, said dental bleaching agent having a concentration in a range of about 1% to about 60% by weight of said dental bleaching gel. 19. An article of manufacture as defined in claim 1, said dental bleaching agent having a concentration in a range of about 3% to about 40% by weight of said dental bleaching gel. 20. An article of manufacture as defined in claim 1, said dental bleaching agent having a concentration in a range of about 5% to about 30% by weight of said dental bleaching gel. 21. An article of manufacture as defined in claim 1, said tackifying agent comprising at least one of polyvinyl pyrrolidone (PVP), carboxypolymethylene, polyethylene oxide, polyacrylic acid, copolymer of polyacrylic acid, polyacrylate, polyacrylamide, copolymer of polyacrylic acid and polyacrylamide, PVP-vinyl acetate copolymer, carboxymethylcellulose, carboxypropylcellulose, polysaccharide gum, or protein. 22. An article of manufacture as defined in claim 1, further comprising a barrier layer comprising a moisture-resistant material adjacent to an outer surface of said adhesive activation composition so as to provide a barrier to saliva or moisture during use. 23. An article of manufacture as defined in claim 22, said barrier layer being flexible so that it will readily conform to the shape of a person's teeth when in use. 24. An article of manufacture as defined in claim 22, said barrier layer comprising at least one of wax, metal foil, paraffin, ethylene-vinyl acetate copolymer, ethylene-vinyl alcohol copolymer, polycaprolactone, polyolefin, polyethylene, high density polyethylene, low density polyethylene, ultra-low density polyethylene, polypropylene, polytetrafluoroethylene, polyester, polycarbonate, polyurethane, polyamide, or polyesteramide. 25. An article of manufacture as defined in claim 22, said barrier layer having a cross-sectional thickness in a range of about 0. 025 mm to about 1.5 mm. 26. An article of manufacture as defined in claim 22, said barrier layer having a cross-sectional thickness in a range of about 0.05 mm to about 1 mm. 27. An article of manufacture as defined in claim 1, further comprising a sealed package within which said adhesive activation composition and bleaching gel are sealed prior to use. 28. A kit for use in desensitizing a person's teeth comprising a plurality of said articles of manufacture according to claim 1. 29. A kit as defined in claim 28, wherein at least some of said articles of manufacture are stacked and internested together. 30. A kit as defined in claim 28, further comprising a barrier layer, or a material used to make a barrier layer, that is positioned adjacent to an outer surface of the adhesive activation composition just prior to use. 31. A method for bleaching a person's teeth comprising obtaining an article of manufacture according to claim 1 and placing it over at least a portion of the person's teeth for a desired time period. 32. An article of manufacture for use in bleaching a person's teeth, comprising: a barrier layer comprising a moisture-resistant material; a substantially dry adhesive activation composition that is sufficiently solid so that it will substantially maintain either a tray-like or a strip-like configuratian so as to be adapted for handling and application to a patient's teeth, said adhesive activation composition being disposed adjacent to said barrier layer and having increased adhesiveness to teeth when moistened by saliva or water, said adhesive activation composition comprising at least one tooth adhesion agent that at least partially contributes to said increased adhesiveness to teeth and at least one bleaching agent activator; and a substantially viscous and tacky dental bleaching gel, adjacent to at least one of said adhesive activation composition or barrier layer, comprising at least one dental bleaching agent, at least one tackifying agent, and a liquid or gel carrier. 33. An article of manufacture as defined in claim 32, said barrier layer having a tray-like configuration comprising a least two sidewalls that define a trough within which the dental bleaching gel resides prior to use. 34. An article of manufacture as defined in claim 33, at least a portion of said trough having a cross section that is approximately U-shaped, V-shaped, L-shaped, rectangular, or trapezoidal. 35. An article of manufacture as defined in claim 33, said barrier layer being initially horseshoe shaped prior to use so as to at least approximately conform to a person's dental arch with minimal longitudinal shaping. 36. An article of manufacture as defined in claim 33, said barrier layer having a substantially straight longitudinal profile prior to use so that longitudinal curving is required when placed over a person's teeth. 37. An article of manufacture as defined in claim 32, said barrier layer being flexible so as to readily conform to the shape of a person's teeth during use. 38. An article of manufacture as defined in claim 32, said barrier layer comprising at least one of wax, metal foil, paraffin, ethylene-vinyl acetate copolymer, ethylene-vinyl alcohol copolymer, polycaprolactone, polyolefin, polyethylene, high density polyethylene, low density polyethylene, ultra-low density polyethylene, polypropylene, polytetrafluoroethylene, polyester, polycarbonate, polyurethane, polyamide, or polyesteramide. 39. An article of manufacture as defined in claim 32, said barrier layer comprising a customized dental tray. 40. An article of manufacture as defined in claim 32, said barrier layer comprising a thin, flexible membrane having no predefined shape, said adhesive layer having sufficiently rigidity so as to a least partially contribute to maintaining said barrier layer in the shape of a dental tray prior to use. 41. An article of manufacture as defined in claim 32, said tooth adhesion agent within said adhesive activation composition comprising at least one of polyvinyl pyrrolidone (PVP), carboxypolymethylene, polyethylene oxide, polyacrylic acid, copolymer of polyacrylic acid, polyacrylate, polyacrylamide, copolymer of polyacrylic acid and polyacrylamide, PVP-vinyl acetate copolymer, carboxymethylcellulose, carboxypropylcellulose, polysaccharide gum, or protein. 42. An article of manufacture as defined in claim 32, said bleaching agent activator within said adhesive activation composition comprising at least one of a base, a metal, a metal compound or an enzyme. 43. An article of manufacture as defined in claim 32, said bleaching agent activator within said adhesive activation composition having a concentration in a range of about 0.01% to about 20% by weight of said adhesive activation composition. 44. An article of manufacture as defined in claim 32, said adhesive activation composition further comprising at least one member selected from the group comprising dental desensitizing agents, remineralizing agent, antimicrobial agents, antiplaque agents, and anti-tartar agents. 45. An article of manufacture as defined in claim 32, said dental bleaching gel further comprising at least one member selected from the group comprising dental desensitizing agents, remineralizing agent, antimicrobial agents, antiplaque agents, and anti-tartar agents. 46. An article of manufacture as defined in claim 32, said dental bleaching gel positioned adjacent to said barrier layer rather than said adhesive composition so as to prevent or inhibit contact between the bleaching agent activator and bleaching gel prior to use. 47. A kit for use in bleaching a person's teeth comprising a plurality of articles of manufacture according to claim 32. 48. A method for bleaching a person's teeth comprising obtaining a dental bleaching device comprising the barrier layer, adhesive activation composition, and dental bleaching gel of claim 32 and then placing said dental bleaching device over at least a portion of the person's teeth for a desired time period. 49. A method of manufacturing an article for use in a dental treatment system that includes a moisture-resistant barrier layer adapted to be placed upon and worn over a treatment composition used in bleaching a person's teeth, comprising: mixing together a tooth adhesion agent, a solvent, and a bleaching agent activator to form an adhesive activation composition intermediate; removing at least a portion of said solvent from said adhesive activation composition intermediate so as to form a substantially solid adhesive composition having increased adhesiveness to teeth when moistened with saliva or water, and that is substantially dry and sufficiently solid so as to be adapted for handling and application to a patient's teeth either with or independent of the moisture-resistant barrier layer, said tooth adhesion agent at least partially contributing to increased adhesiveness to teeth; and placing a substantially viscous and tacky dental bleaching gel adjacent to the adhesive layer for application to the patient's teeth when the adhesion agent is placed on and worn on the teeth under a moisture-resistant barrier layer. 50. A method as defined in claim 49, further comprising placing or forming a barrier layer adjacent to said adhesive activation composition. 51. A method of manufacturing an article for use in bleaching teeth, comprising; mixing together a tooth adhesion agent, a solvent, and a bleaching agent activator to form an adhesive activation composition intermediate; placing the adhesive activation composition intermediate adjacent to a barrier layer; removing at least a portion of said solvent from said adhesive activation composition intermediate so as to form a substantially solid adhesive composition having increased adhesiveness to teeth when moistened with saliva or water, and that is substantially dry and sufficiently solid so that it will essentially maintain either a strip-like or a tray-like configuration, said tooth adhesion agent at least partially contributing to increased adhesiveness to teeth; and placing a substantially viscous and tacky dental bleaching gel adjacent to the adhesive layer for application to the patient's teeth when the adhesion agent is placed on and worn on the teeth under the moisture-resistant barrier layer.
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