최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0085150 (2002-02-27) |
발명자 / 주소 |
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출원인 / 주소 |
|
인용정보 | 피인용 횟수 : 348 인용 특허 : 40 |
An external mixer assembly is provided which externally mixes and delivers a first and a second component of a biological adhesive to tissues or organs for sealing wounds, stopping bleeding and the like. The first and second components are mixed immediately after exiting from separate outlet ports d
An external mixer assembly is provided which externally mixes and delivers a first and a second component of a biological adhesive to tissues or organs for sealing wounds, stopping bleeding and the like. The first and second components are mixed immediately after exiting from separate outlet ports disposed in fluid communication with component reservoirs. In on embodiment, the external mixer assembly includes a housing having a housing head for enclosing therein a first reservoir containing the first component, and a second reservoir containing the second component. The housing further includes a discharge nozzle defining a longitudinal axis for enclosing therein a conduit assembly having a first and a second conduit in communication with the first and second reservoir, respectively. A deflector assembly is connected to the discharge nozzle. The deflector assembly includes a deflector plate to provide a space for initial mixing of the first and second components. The deflector plate is oriented in generally parallel juxtaposed relation distal to the distal face of the discharge nozzle. The first and second components are preferably fibrinogen and thrombin which intermix to form a fibrin sealant.
What is claimed is: 1. A fluid delivery system for dispensing a multicomponent biological adhesive having at least a first component and a second component, the system comprising: a housing configured to receive a plurality of reservoirs; a discharge nozzle housing a conduit assembly having a plur
What is claimed is: 1. A fluid delivery system for dispensing a multicomponent biological adhesive having at least a first component and a second component, the system comprising: a housing configured to receive a plurality of reservoirs; a discharge nozzle housing a conduit assembly having a plurality of conduits with a proximal end thereof in respective fluid communication with separate of said reservoirs, a distal end of said conduits defining at least two exit openings, wherein each of said plurality of reservoirs includes a sealable opening configured for being penetrated by a proximal end of a respective one of said plurality of conduits; and a deflector assembly provided on said housing, said deflector assembly having a deflector plate substantially parallel with said at least two exit openings, said deflector plate displaced at a distance from a distal-most end of said housing and oriented to deflect said first and second components after exiting from said at least two exit openings. 2. The system of claim 1, wherein said deflector plate is oriented in general parallel relation to a distal face of said discharge nozzle. 3. The system of claim 1, wherein a first of said at least one exit opening and a second of said at least one exit opening are independent, such that said first and second components deflect and intermix external to said discharge nozzle against said deflector plate. 4. The system of claim 1, wherein said first component is a thrombin solution and said second component is a fibrinogen solution, whereby said biological adhesive is a fibrin sealant. 5. The system of claim 1, wherein said biological adhesive comprises a predetermined ratio of said first component to said second component. 6. The system of claim 1, wherein said housing includes a housing head for storing said plurality of reservoirs therein. 7. The system of claim 1, wherein the at least two exit openings are at an angle. 8. A fluid delivery system for dispensing a first and a second component of a biological adhesive, the system comprising: a housing configured to receive a plurality of reservoirs storing the first and second components; a nozzle assembly housed within a housing, said nozzle assembly having at least two dispensing conduits for dispensing the first component and the second component, wherein each of said plurality of reservoirs includes a sealable opening configured for being penetrated by a proximal end of the at least two dispensing conduits; and a deflector assembly connected to the nozzle assembly, said deflector assembly having a deflector plate to deflect said first and second components after being dispensed from a distal exit of a respective dispensing conduit of said at least two dispensing conduits, said deflector plate displaced at a distance from a distal-most end of said housing and being substantially parallel with said distal exits. 9. The system of claim 8, wherein said deflector plate is oriented in general parallel relation to a distal face of said nozzle assembly. 10. The system of claim 8, wherein a first of said at least one dispensing conduit and a second of said at least one dispensing conduit are independent, such that said first and second components deflect and intermix external to said nozzle assembly against said deflector plate. 11. The system of claim 8, wherein said first component is a thrombin solution and said second component is a fibrinogen solution, whereby said biological adhesive is a fibrin sealant. 12. The system of claim 8, wherein said biological adhesive comprises a predetermined ratio of said first component to said second component. 13. The system of claim 8, wherein said housing includes a housing head for storing a plurality of reservoirs therein, each of said plurality of reservoirs storing one of the first and the second components. 14. The system of claim 8, wherein the distal exits are at an angle. 15. A fluid delivery system for dispensing a multicomponent biological adhesive, the system comprising: a conduit assembly housed within a housing, said conduit assembly having two conduits each having an exit opening; a reservoir assembly having a first reservoir containing the first adhesive component and a second reservoir containing the second adhesive component, the first and second reservoirs being in fluid communication with a respective one of the two conduits, wherein the first and second reservoirs each include a sealable opening configured for being penetrated by a proximal end of the two conduits; and a deflector assembly having a deflector plate displaced at a distance from a distal end of said housing for receiving the first and the second adhesive components from the two conduits and deflecting the first and second adhesive components prior to dispensing to an application site, wherein said deflector plate is substantially parallel to each of said exit openings. 16. The system of claim 15, wherein said deflector plate is oriented in general parallel relation to a distal face of said conduit assembly. 17. The system of claim 15, wherein the exit openings are at an angle.
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