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특허 상세정보

Pharmaceutical compositions and methods for managing skin conditions

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-033/40    A61K-031/35    A61K-031/495   
미국특허분류(USC) 424/616; 514/248; 514/739; 514/460
출원번호 US-0093443 (2002-03-11)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Kenyon &
인용정보 피인용 횟수 : 32  인용 특허 : 25
초록

This application relates to a stable pharmaceutical composition and methods for the cleansing of skin to facilitate the prevention, treatment, and management of skin conditions, such as seborrheic dermatitis, psoriasis, folliculitis, rosacea, perioral dermatitis, acne, impetigo and other inflammatory skin conditions, and the like, including a sufficient amount of an acidic component of a hydroxyacid or tannic acid, or a pharmaceutically acceptable salt thereof, to exfoliate a portion of the skin, a sufficient amount of stabilized hydrogen peroxide to fac...

대표
청구항

What is claimed is: 1. A skin cleansing pharmaceutical composition comprising: an acidic component comprising a hydroxy acid or tannic acid, or a pharmaceutically acceptable salt thereof, present in an amount greater than about 4 weight percent sufficient to exfoliate at least a portion of the skin; hydrogen peroxide in an amount sufficient to cleanse the skin without substantial irritation thereof; and metronidazole. 2. The pharmaceutical composition of claim 1, wherein the composition further comprises a pharmaceutically acceptable carrier or excip...

이 특허에 인용된 특허 (25)

  1. Cook William J. (New York NY) Wisniewski Karen L. (Bound Brook NJ) Dixit Nagaraj S. (Plainsboro NJ) Rao Nandakumar S. (Hockessin DE). Acidic disinfectant all-purpose liquid cleaning composition. USP1991045008030.
  2. Jarrett Michael (Houston TX). Amphoteric acetates and glycinates as shale stabilizing surfactants for aqueous well fluids. USP1997015593952.
  3. Sawaya Assad S. (9 Lyn La. Baiting Hollow NY 11933). Antifungal formulation. USP1996055519059.
  4. Yu Ruey J. (Ambler PA) Van Scott Eugene J. (Abington PA). Antiodor, antimicrobial and preservative compositions and methods of using same. USP1997065641475.
  5. Rovati Romeo A. (Barcelona ESX) Mestres Ricardo C. (Barcelona ESX). Dichloro-substituted imidazole derivatives as antifungal agents. USP1993015177099.
  6. Hall Larry (Nazareth PA) Chiang Michael Y. (Flemington NJ) Meyer Judith M. (Somerville NJ). Disinfectants and sanitizers with reduced eye irritation potential. USP1996085547990.
  7. Bansemir Klaus (Langenfeld DEX) Disch Karlheinz (Haan DEX) Hachmann Klaus (Hilden DEX) Lehmann Rudolf (Leichlingen DEX) Biermann Manfred (Muelheim DEX) Schnegelberger Harald (Leichlingen DEX). Disinfectants and their use for disinfecting the skin and mucous membrane. USP1990024900721.
  8. Claeys DaniA. (Mortsel BEX) Reyniers Albert A. (Kontich BEX) Janssens Wilhelmus (Aarschot BEX). Etch bleaching liquid with iron(III)ions. USP1980054203765.
  9. Dresdner ; Jr. Karl P. (235 W. 48th St. ; Apt. #18N New York City NY 10036) Dangman Kenneth H. (400 Riverside Dr. ; Apt. #1A New York City NY 10032) Jazlowiecki Edward A. (15 Sachems Trail West Simsb. Flexible protective medical gloves and methods for their use. USP1994105357636.
  10. af Ekenstam, Bo T.; Glantz, Per-Olof; Larsson, Kare. Germicidal composition. USP1985124557935.
  11. Sklar Jerald L.. Glycolic acid and tretinoin formulation for the treatment of acne. USP1999015861432.
  12. Burke Michael R. (Somerset NJ) Prencipe Michael (East Windsor NJ) Buchanan James M. (Mercerville NJ). High foaming rheologically stable non-irritating oral composition. USP1994035296215.
  13. Devillez Richard L.. Method and composition for skin treatment. USP1999095958984.
  14. Ganci Salvatore (New York NY). Method of promoting tissue growth. USP1984034438102.
  15. Schmidt William (Woodbury MN). Noncontaminating antimicrobial composition. USP1992085139788.
  16. Barton Stephen Peter (Nottingham GB2) Galley Edward (Nottingham GB2). Oral hygiene composition. USP1997125695745.
  17. Bowing Walter Grosse (Dusseldorf DT) Mrozek Hinrich (Dusseldorf DT) Schlussler Hans-Joachim (Haan DT) Tinnefeld Bernd (Velbert DT) Vogele Peter (Sindelfingen DT). Peroxy-containing microbicides stable in storage. USP1977094051059.
  18. Howard Murad. Pharmaceutical compositions and methods for managing skin conditions. USP2002056383523.
  19. Murad Howard. Pharmaceutical compositions and methods for managing skin conditions. USP2000066071541.
  20. Murad Howard. Pharmaceutical compositions and methods for managing skin conditions. USP2001106296880.
  21. Oliver Benjamin. Skin treatment composition. USP1999025869062.
  22. Hopkins Quentin G. (Charleston WV) Browning Jhonce N. (Charleston WV). Stabilization of high purity hydrogen peroxide. USP1985084534945.
  23. Scholz Matthew T. ; Asmus Robert A. ; Charpentier Jill R.. Stable hydroalcoholic compositions. USP1999095951993.
  24. Bowing Walter Grosse (Dusseldorf DT) Mrozek Hinrich (Dusseldorf DT) Schlussler Hans-Joachim (Haan DT) Tinnefeld Bernd (Velbert DT) Vogele Peter (Sindelfingen DT). Stable peroxy-containing microbicides. USP1977094051058.
  25. Burke John Jerome (Sparta NJ) Gorczyca Joanne Paula (Livonia MI). Stable salicylic acid and peroxide containing skin and hair cleanser composition. USP1997125693318.

이 특허를 인용한 특허 피인용횟수: 32

  1. Huang, Alexander L.; Wu, Gin. Antibacterial having an extract of pomegranate combined with hydrogen peroxide. USP2014058734867.
  2. Choi, Jennifer Hagyoung Kang; Yang, Chunlin; Sun, Ying; Fang, Carrie H.; Hauschild, James E.; Creasey, Abla A.. Medical devices with galvanic particulates. USP2015069044397.
  3. Huang, Alexander L; Wu, Gin. Method of killing a bacteria with a plant-based biocidal solution. USP2017059636361.
  4. Huang, Alexander L.; Wu, Gin. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide. USP2015119192635.
  5. Huang, Alexander L; Wu, Gin. Methods of inhibiting a bacterial virulence in a subject. USP2017039603883.
  6. Huang, Alexander L; Wu, Gin. Methods of treating a gastrointestinal spasm associated with chemotherapy or radiation therapy. USP2016089408869.
  7. Huang, Alexander L; Wu, Gin. Methods of treating a treatment-resistant gastrointestinal spasm. USP2018039907818.
  8. Huang, Alexander L; Wu, Gin. Methods of treating a treatment-resistant gastrointestinal spasm with an oxidized tannin. USP20180810039784.
  9. Huang, Alexander L; Wu, Gin. Methods of treating drug side-effects that include a gastrointestinal spasm. USP2015079089596.
  10. Huang, Alexander L; Wu, Gin. Methods of treating gastroesophageal reflux disease. USP2017039603871.
  11. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms. USP2014058716351.
  12. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having Crohn's Disease or ulcerative colitis. USP2014058716353.
  13. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having colorectal cancer. USP2014078772352.
  14. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms in a subject having diverticulitis. USP2014078772350.
  15. Huang, Alexander L; Wu, Gin. Methods of treating gastrointestinal spasms triggered by stress. USP2014088809399.
  16. Huang, Alexander L; Wu, Gin. Methods of treating malnutrition. USP2015028946304.
  17. Huang, Alexander L; Wu, Gin. Methods of treating necrotic enteritis. USP2015059023895.
  18. Sun, Ying; Wu, Jeffrey; Liu, Jue-Chen; Phipps, Joseph B.. Methods of treating pores on the skin with electricity. USP2014058734421.
  19. Chen, Xin; Hermsmeier, Maiko C.; Lac, Diana; Thomas, Douglas W.; Yam, Noymi; Yamamoto, Akira. Pharmaceutical tetracycline composition for dermatological use. USP2018039918998.
  20. Huang, Alexander L.; Wu, Gin. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites. USP2014058722040.
  21. Hunt, Jr., Clinton; Man, Victor Fuk-Pong; Lentsch, Steven Eugene; Tan, Lylien; Killeen, Yvonne Marie; Everson, Terrence P.. Stable liquid manual dishwashing compositions containing enzymes. USP2017089745543.
  22. Huang, Alexander L; Wu, Gin. Tannin formulation for treating GI spasms. USP2014058716352.
  23. Huang, Alexander L; Wu, Gin. Tannin formulation for treating GI spasms in a subject having Crohn's disease or ulcerative colitis. USP2014078765818.
  24. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms in a subject having colorectal cancer. USP2014098822544.
  25. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms in a subject having diverticulitis. USP2014078772351.
  26. Huang, Alexander L; Wu, Gin. Tannin formulation for treating gastrointestinal spasms triggered by stress. USP2014098822545.
  27. Huang, Alexander L; Wu, Gin. Tannin formulation for treating malnutrition. USP2015028952072.
  28. Huang, Alexander L; Wu, Gin. Therapeutic composition produced using Camellia sinensis leaves and hydrogen peroxide. USP2013118586110.
  29. Huang, Alexander L.; Wu, Gin. Therapeutic composition produced using punica granatum and hydrogen peroxide. USP2013018343552.
  30. Sun, Ying; Liu, Jue-Chen; Wu, Jeffrey M.; Hauschild, James E.. Topical composition containing galvanic particulates. USP2013078475689.
  31. Huang, Alexander L.; Wu, Gin. Treating a bacteria-induced gastric disorder with a mixture having pomegranate and hydrogen peroxide. USP2014058722116.
  32. Huang, Alexander L; Wu, Gin. Treating inflammation with a binding system. USP2014078790640.