최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
---|---|
국제특허분류(IPC7판) |
|
출원번호 | US-0127395 (2002-04-19) |
발명자 / 주소 |
|
출원인 / 주소 |
|
인용정보 | 피인용 횟수 : 221 인용 특허 : 632 |
A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoids may drive the lancet using elect
A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoids may drive the lancet using electromagnetic force. Advancement and retraction of a lancet may be controlled by a feedback loop monitoring the position and velocity of the lancet embodiments of the lancet driver can be configured to follow a predetermined tissue lancing profile. Embodiments of the invention include a lancet and method for using a lancet to maintain the patency of the wound tract once the lancet has cut into the skin.
What is claimed is: 1. A method of lancing the skin of a patient to bring a blood sample to a tissue surface, the method comprising: (a) providing a tissue penetration element having a tip configured to penetrate tissue; (b) disposing the tissue penetration element in proximity to the tissue of th
What is claimed is: 1. A method of lancing the skin of a patient to bring a blood sample to a tissue surface, the method comprising: (a) providing a tissue penetration element having a tip configured to penetrate tissue; (b) disposing the tissue penetration element in proximity to the tissue of the patient; (c) driving the tissue penetration element distally towards the tissue of the patient; (d) making contact between the tip and the tissue of the patient; (e) advancing the tip into the tissue during a penetration stroke to a position of maximum inward displacement; (f) displacing the tissue penetration element proximally over a withdrawal stroke at an average velocity that is substantially lower than an average velocity of the tissue penetration element during the penetration stroke, wherein the average velocity of the tissue penetration element during the penetration stroke is about 100 to about 1000 times greater than the average velocity of the tissue penetration member during the withdrawal stroke; and (g) withdrawing the tissue penetration element during a withdrawal stroke at a maximum velocity of up to about 0.02 meters per second. 2. The method of claim 1 further comprising allowing the tissue penetration element to settle upon reaching the point of maximum inward penetration for about 1 to about 2000 milliseconds, wherein no driving force is imposed on the tissue penetration element while settling. 3. The method of claim 1 further comprising allowing the tissue penetration element to settle upon reaching the point of maximum inward penetration for about 8 to about 200 milliseconds, wherein no driving force is imposed on the tissue penetration element while settling. 4. The method of claim 1 further comprising allowing the tissue penetration element to settle upon reaching the point of maximum inward penetration for about 50 to about 2000 milliseconds, wherein no driving force is imposed on the tissue penetration element while settling. 5. The method of claim 1 further comprising allowing the tissue penetration element to settle upon reaching the point of maximum inward penetration for about 50 to about 200 milliseconds, wherein no driving force is imposed on the tissue penetration element while settling. 6. The method of claim 1 wherein the average velocity of the tissue penetration element during the withdrawal stroke during which the tissue penetration element is moving proximally relative to tissue in contact with the tissue penetration element is about 0.001 to about 0.01 meters per second. 7. The method of claim 1 wherein the average velocity of the tissue penetration element during the penetration stroke from the point of contact with the tissue until the position of maximum inward displacement is about 2 to about 4 meters per second and wherein the average velocity of the tissue penetration element during the withdrawal stroke during which the tissue penetration element is moving proximally relative to tissue in contact with the tissue penetration element is about 0.001 to about 0.01 meters per second. 8. The method of claim 1 wherein the tissue comprises the skin of a human patient and the tip penetrates the skin to at the position of maximum inward displacement to a depth of about 0.5 to about 3.0 mm from an outer surface of the skin. 9. The method of claim 1 further comprising selecting a desired lancing velocity profile from a set of alternative lancing velocity profiles having characteristic phases for tissue penetration element advancement and retraction. 10. The method of claim 1 further comprising providing a lancing device having a position feedback loop far monitoring longitudinal displacement of said tissue penetration element and for modulating a controllable driver to provide a predetermined tissue lancing profile having characteristic phases for tissue penetration element advancement and retraction. 11. The method of claim 1 further comprising acquiring tissue data based on an interaction between the tissue penetration element and the tissue during at least a portion of the lancing cycle. 12. The method of claim 1 further comprising withdrawing the tissue penetration element from the skin of the patient at a velocity sufficiently slow to allow blood flowing from severed blood vessels to flow into a channel in the patient tissue created by the tip of the penetration member to follow the tip out of the wound channel and flow to a surface of the tissue. 13. The method of claim 1 wherein an electromagnetic force generating member is used to drive the tissue penetration member. 14. The method of claim 13 further comprising using a permanent magnet disposed at a proximal end of a magnetically active region of the electromagnetic force generating member for zeroing the position of a magnetic member disposed at least partially in the magnetically active region while the tissue penetration device is inactive. 15. The method of claim 13 further comprising using a position sensor disposed adjacent a driver coil pack in the force generating member, said position sensor comprising an optical reader and an optical flag secured to a proximal section of a coupler shaft of the force generating member, with the optical flag configured to slide axially adjacent the optical reader and to measure the position of the coupler shaft relative to the position sensor and driver coil pack. 16. The method of claim 1 further comprising using a feedback loop position sensor configured to measure the position and control the velocity of the tissue penetration element. 17. The method of claim 1 further comprising using a feedback loop that includes a light detecting sensor and a light emitter for monitoring the relative position of the tissue penetration element comprising a reflective surface on a proximal end such that the light emitter emits light that is reflected from the reflective surface to the sensor. 18. The method of claim 1 further comprising: measuring a velocity of a moving tissue penetration element at a known position; comparing the measured velocity of the tissue penetration element with an appropriate velocity for the tissue penetration element at the known position; and applying a force to the tissue penetration element to adjust the velocity of the tissue penetration element. 19. The method of claim 1 further comprising: monitoring position and speed of the tissue penetration element as the tissue penetration element moves in a first direction; adjusting the application of force to the tissue penetration element as the tissue penetration element moves in the first direction to achieve a desired speed of the tissue penetration element; adjusting the application of force to the tissue penetration element when the tissue penetration element contacts the tissue so that the tissue penetration element penetrates the tissue within a desired range of speed. 20. The method of claim 1 further comprising: applying a braking force to the tissue penetration element to decelerate the tissue penetration element as the tissue penetration element moves in the first direction toward the tissue such that the tip of the tissue penetration element penetrates the tissue to a desired depth. 21. A method of lancing the skin of a patient to bring a blood sample to a tissue surface, the method comprising: (a) providing a tissue penetration element having a tip configured to penetrate tissue; (b) disposing the tissue penetration element in proximity to the tissue of the patient; (c) driving the tissue penetration element distally towards the tissue of the patient; (d) making contact between the tip and the tissue of the patient; (e) advancing the tip into the tissue during a penetration stroke to a position of maximum inward displacement; (f) displacing the tissue penetration element proximally over a withdrawal stroke at an average velocity that is substantially lower than an average velocity of the tissue penetration element during the penetration stroke; (g) withdrawing the tissue penetration element during a withdrawal stroke at a maximum velocity of up to about 0.02 meters per second; and using a position sensor disposed adjacent a driver coil pack in the force generating member, said position sensor comprising an optical reader and an optical flag secured to a proximal section of a coupler shaft of the force generating member, with the optical flag configured to slide axially adjacent the optical reader and to measure the position of the coupler shaft relative to the position sensor and driver coil pack. 22. A method of lancing the skin of a patient to bring a blood sample to a tissue surface, the method comprising: (a) providing a tissue penetration element having a tip configured to penetrate tissue; (b) disposing the tissue penetration element in proximity to the tissue of the patient; (c) driving the tissue penetration element distally towards the tissue of the patient; (d) making contact between the tip and the tissue of the patient; (e) advancing the tip into the tissue during a penetration stroke to a position of maximum inward displacement; (f) displacing the tissue penetration element proximally over a withdrawal stroke at an average velocity that is substantially lower than an average velocity of the tissue penetration element during the penetration stroke; (g) withdrawing the tissue penetration element during a withdrawal stroke at a maximum velocity of up to about 0.02 meters per second; and using a feedback loop that includes a light detecting sensor and a light emitter for monitoring the relative position of the tissue penetration element comprising a reflective surface on a proximal end such that the light emitter emits light that is reflected from the reflective surface to the sensor.
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.