|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||514/002; 514/003; 514/021|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 1 인용 특허 : 2|
The present invention proposes formative agent of protein complex, in which a polyphenol is useful component, and the agent is useful as gene complex, cell adhesion inhibitor or immune tolerogen. The polyphenol of forming the agent is selected from catechin group consisting of epigallocatechin-gallate, tannic acids, or proanto-dianisidine, a protein of the protein complex is selected from proteins consisting of animal proteins composed of polypeptide chain of peptide-combined amino acids, vegetative proteins, nucleus proteins, glycogen proteins, lipo-pro...
I claim: 1. Method for forming a protein complex for a sustained release preparation drug, said method comprising treating a protein of said protein complex with a protein complex formative agent comprising a polyphenol, wherein said protein is selected from the group consisting of insulin, interferon α, epithelium cell growth factor (EGF), and allergen protein; and said polyphenol is a pure epigallocatechin gallate. 2. Method according to claim 1, wherein the weight ratio of said protein to said polyphenol is in the range of about 15-1000. 3...