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A method and apparatus for processing an image of a tissue sample microarray include placing a plurality of tissue samples in an array on a microscope slide. The tissue samples are then simultaneously and uniformly treated, as by staining. Images of the tissue making up the microarray are captured a

A method and apparatus for processing an image of a tissue sample microarray include placing a plurality of tissue samples in an array on a microscope slide. The tissue samples are then simultaneously and uniformly treated, as by staining. Images of the tissue making up the microarray are captured and stored together with identifying information related thereto. The images may be displayed from the digital storage medium using a programmed processor which can select various magnifications for display. The images also can be accessed by network and remotely.

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What is claimed is: 1. A method of analyzing dots having cellular material and arranged in a microarray comprising: providing a microscope slide with a microarray of dots thereon arranged in columns and rows; acquiring a low magnification image of the microarray showing the magnified dots and their

What is claimed is: 1. A method of analyzing dots having cellular material and arranged in a microarray comprising: providing a microscope slide with a microarray of dots thereon arranged in columns and rows; acquiring a low magnification image of the microarray showing the magnified dots and their respective positions in the microarray; using low magnification image of the dots and their respective locations to locate the dots within the microarray for analysis; and performing an analysis for a dot image located from the low magnification image. 2. A method in accordance with claim 1 comprising: indexing the low magnification image of the dot and the analysis thereof with a unique identifier associated with the row and column location of the dot within the microarray on the microscope slide. 3. A method of analyzing dots having cellular material and arranged in a microarray comprising: providing a microscope slide with a microarray of dots thereon arranged in columns and rows; acquiring a low magnification image of the microarray showing the magnified dots and their respective positions in the microarray; using low magnification image of the dots and their respective locations to locate the dots within the microarray for analysis; performing an analysis for a dot image located from the low magnification image; and providing a higher magnification image of the located dot and performing an analysis on the high magnification image of the located dot. 4. A method in accordance with claim 3 comprising: performing the analysis by making a quantitative measurement on the located dot. 5. A method in accordance with claim 3 comprising: forming a data structure for a dot comprising data for dot specimen identification, column and row location, and the analysis made for the dot. 6. A method in accordance with claim 3 comprising: forming a data base with data structures having the dot images associated with a unique specimen identifier so that the dot images can be later identified, accessed and displayed. 7. A method in accordance with claim 3 wherein the low magnification image of the dots comprises: acquiring successive, adjacent images of the microarray and assembling them together into a composite image. 8. A method in accordance with claim 7 comprising: tiling of successive and adjacent images of single fields of view to form the composite image. 9. A method of analyzing dots having cellular material and arranged in a microarray comprising: providing a microscope slide with a microarray of dots thereon arranged in columns and rows; acquiring a low magnification image of the microarray showing the magnified dots and their respective positions in the microarray; using low magnification image of the dots and their respective locations to locate the dots within the microarray for analysis; performing an analysis for a dot image located from the low magnification image; and acquiring and tiling adjacent high magnification images of a single field of view for each dot located from the low magnification image of the microarray of dots. 10. A method in accordance with claim 9 comprising: performing a quantitative measurement analysis on the tiled high magnification images; and indexing the high magnification images and the low magnifications with unique identifiers associated with the row and column position of the associated dot on the microscope slide. 11. A method of analyzing dots having cellular material and arranged in a microarray comprising: providing a microscope slide with a microarray of dots thereon arranged in columns and rows; acquiring a low magnification image of the microarray showing the magnified dots and their respective positions in the microarray; using low magnification image of the dots and their respective locations to locate the dots within the microarray for analysis; performing an analysis for a dot image located from the low magnification image; providing several microarrays on the same microscope slide with each of the microarrays having hundreds of dots thereon; forming a database for the images of the dots; and indexing the respective dot images with a unique identifier associated with the location of dots in each of the microarrays on the microscope slide. 12. An apparatus for analyzing specimen dots having cellular material and arranged in a microarray on a microscope slide, the apparatus comprising: a microscope for providing magnified images of the dots from the specimen dots on the microscope slide; an imager for providing signals representative of a magnified image for each of the specimen dots; a display coupled to the imager and operable to display a microarray of magnified dot images in their respective positions within the microarray to assist in locating a specimen dot image for analysis; and a processor connected to the display and operable to index an analysis made from the magnified dot image with the specimen dot in the microarray on the microscope. 13. An apparatus in accordance with claim 12 wherein the imager displays adjacent magnified dot images positioned adjacent one another to form a composite magnified image of the dot images, each in positions associated with the specimen dots in the microarray. 14. An apparatus in accordance with claim 12 wherein: the microscope and imager are operable by the processor to provide a high magnification image of each specimen dot in the microarray. 15. An apparatus in accordance with claim 14 wherein: the processor stores low magnification images and high magnification images and indexes them to their associated specimen dot in the microarray on the microscope slide. 16. A method of capturing images of a microarray of tissue samples on a microscope at low and high magnifications for retrieval and display, the method comprising: acquiring a low magnification image of the microarray showing a grid of tissue samples from the slide; selecting a sub-array of a grid of tissue images displayed at low magnification; acquiring high magnification images of the located tissue samples within the subarray; and associating unique identification information with each of the respective tissue sample images in the microarray so that individual tissue samples in the microarray can be selected and high magnification images thereof be acquired for evaluation. 17. A method in accordance with claim 16 wherein the associating of unique identification information with each tissue sample comprises: associating a row and column index for the tissue sample images with row and column positions of the tissue samples in the microarray. 18. A method in accordance with claim 16 comprising: performing a quantitative analysis from the tissue sample images. 19. A method in accordance with claim 18 wherein the quantitative analysis comprises: making an evaluation of cellular structure and tissue architecture. 20. A method in accordance with claim 18 wherein the quantitative analysis comprises: discovery of genes and targeting genetic probes for attachment to particular tissue regions and molecules. 21. A method in accordance with claim 18 wherein the quantitative analysis comprises: using antibody-based probes. 22. A method in accordance with claim 16 wherein the low magnification image of the microarray comprises: tiling of adjacent field of view images acquired at low magnification to be used to provide a composite low magnification image of the micro-array. 23. A method in accordance with claim 16 comprising: displaying a grid scanning pattern related to image tiling at high magnification for each of the respective tissue samples. 24. A method in accordance with claim 16 comprising: providing high magnification images of the tissue specimen and performing assays thereon. 25. An apparatus for capturing images of a microarray of tissue samples on a microscope slide at low and high magnifications for retrieval and display, the apparatus comprising: a microscope for providing low and high magnification views from tissue samples on the microscope slide; an imager for acquiring images of the tissue samples; a display for displaying acquired images from the imager; a processor coupled to the imager; the processor being operable for selecting and displaying a sub-array of a grid of tissue images at low magnification; the processor being operable with imager and display for acquiring high magnification images of tissue samples in the microarray; and the processor operable for associating index information with the low magnification images so that individual tissue samples in the microarray can be accessed for evaluation. 26. An apparatus in accordance with claim 25 comprising: the processor being operable for storing the position of each of the tissue sample in the array in both X and Y coordinates and in row and column locations. 27. An apparatus in accordance with claim 25 comprising: the processor being operable for tiling of adjacent fields of view images of a sample into a composite, high magnification view of a tissue sample. 28. An apparatus in accordance with claim 25 comprising: the processor being operable for tiling adjacent fields of view images acquired at low magnification into a composite, low magnification view of the microarray. 29. An apparatus in accordance with claim 25 comprising: the display displaying simultaneously to a viewer a low magnification image of the microarray and a high magnification image of at least a portion of one of the tissue samples. 30. An apparatus in accordance with claim 25 comprising: a moveable marker displayed to the user and movable by the user to a center location on a circular tissue sample to locate the center of a circular tissue sample. 31. An apparatus in accordance with claim 25 comprising: the processor operating the display to display center markers at uniformly spaced positions on which the microarray samples should be centered if properly positioned at uniform locations in the grid. 32. An apparatus in accordance with claim 25 comprising: the processor operating to the display for displaying a grid over each of the tissue samples in the sub-array. 33. An apparatus in accordance with claim 25 comprising: the display being operable for simultaneously displaying both high and low magnification images. 34. A data structure for a microarray of tissue samples on a microscope slide comprising: low magnification image data being embodied in a computer-readable storage medium for providing an image at low magnification of the microarray of tissue samples on a microscope slide; high magnification image data being embodied in a computer-readable storage medium for providing an image at high magnification of a tissue sample for evaluation; data being embodied in a computer-readable storage medium for connecting the high magnification data for a tissue sample image with the low magnification image of the same tissue sample in the microarray; and index identification data being embodied in a computer-readable storage medium for each of the tissue sample images in the microarray to identify the tissue sample image with the tissue sample in the microarray. 35. A data structure in accordance with claim 34 comprising: data being embodied in a computer-readable storage medium from a quantitative analysis of the tissue sample image within the microarray. 36. A data structure in accordance with claim 34 wherein the low magnification image data comprises: image tile data being embodied in a computer-readable storage medium acquired for adjacent fields of view from the microscope usable to form a low magnification composite image of the microarray. 37. A data structure in accordance with claim 34 wherein the high magnification image comprises: image tile data being embodied in a computer-readable storage medium for adjacent portions of a tissue sample for being stitched together to form a composite high magnification image for each tissue sample. 38. A data structure in accordance with claim 34 wherein the index identification data comprises: row and column data being embodied in a computer-readable storage medium for each image to associate the image with a tissue sample in the microarray. 39. A data structure in accordance with claim 34 comprising: stored data information for use in remote manipulating into view of both the low magnification image of the microarray and a high magnification image from at least a portion of the tissue sample selected for viewing. 40. A data structure in accordance with claim 34 comprising: data stored in a computer-readable storage medium to locate each of several microarrays on a microscope slide and to locate within each microarray image the low magnification tissue images at the same precise positions in the grid as occurs in each microarrays on the microscope slide. 41. A data structure in accordance with claim 40 wherein the data stored for the low magnification image of a tissue sample dot in a grid of data on the microarray accurately positions an irregularly spaced tissue sample dot relative to uniform grid spacing where the non-uniform spacing occurs for the tissue dot on the slide. 42. A data structure for a microarray of tissue sample images and identification information for each of the tissue samples in the microarray comprising: low magnification, image data being embodied in a computer-readable storage medium for adjacent tiles of sub-arrays of tissue samples; information data being embodied in a computer-readable storage medium to align adjacent image tiles into a composite image of the microarray of samples; quantitative analysis data being embodied in a computer-readable storage medium for the tissue samples of the microarray; and identification data being embodied in a computer-readable storage medium for each of the tissue samples in the microarray to allow retrieval of the quantitative analysis data and retrieval of a specifically identified tissue sample image for display. 43. A data structure for a microarray of tissue sample images and identification information for each of the tissue samples in the microarray comprising: low magnification, image data being embodied in a computer-readable storage medium for adjacent tiles of sub-arrays of tissue samples; information data being embodied in a computer-readable storage medium to align adjacent image tiles into a composite image of the microarray of samples; quantitative analysis data being embodied in a computer-readable storage medium for the tissue samples of the microarray; identification data for each of the tissue samples in the microarray to allow retrieval of the quantitative analysis data being embodied in a computer-readable storage medium and retrieval of a specifically identified tissue sample image for display; and high magnification image data being embodied in a computer-readable storage medium and comprising image tile data for adjacent fields of view images for each tissue sample. 44. A data structure in accordance with claim 43 comprising: information data being embodied in a computer-readable storage medium stored to align adjacent high magnification, image tiles for a tissue sample to allow scrolling of adjacent high magnification images into view. 45. A data structure for a microarray of tissue sample images and identification information for each of the tissue samples in the microarray comprising: low magnification, image data being embodied in a computer-readable storage medium for adjacent tiles of sub-arrays of tissue samples; information data being embodied in a computer-readable storage medium to align adjacent image tiles into a composite image of the microarray of samples; quantitative analysis data being embodied in a computer-readable storage medium for the tissue samples of the microarray; identification data being embodied in a computer-readable storage medium for each of the tissue samples in the microarray to allow retrieval of the quantitative analysis data and retrieval of a specifically identified tissue sample image for display; high magnification image data being embodied in a computer-readable storage medium for displaying high magnification from the tissue samples; and data being embodied in a computer-readable storage medium associating the low magnification image data of a tissue sample with the high magnification image data for displaying a high magnification view from a portion of a tissue sample being displayed at low magnification. 46. A data structure for a microarray of tissue sample images and identification information for each of the tissue samples in the microarray comprising: low magnification, image data being embodied in a computer-readable storage medium for adjacent tiles of sub-arrays of tissue samples; information data being embodied in a computer-readable storage medium to align adjacent image tiles into a composite image of the microarray of samples; quantitative analysis data being embodied in a computer-readable storage medium for the tissue samples of the microarray; identification data being embodied in a computer-readable storage medium for each of the tissue samples in the microarray to allow retrieval of the quantitative analysis data and retrieval of a specifically identified tissue sample image for display; high magnification image data being embodied in a computer-readable storage medium for displaying high magnification from the tissue samples; and stored data information being embodied in a computer-readable storage medium for use in remote manipulation into view of both the high magnification and low magnification images for a tissue sample selected. 47. An apparatus for producing a low magnification image of a microarray of tissue samples and high magnification images of adjacent portions within each tissue sample, comprising: a microscope for carrying a microscope slide having a microarray of tissue samples; an imager connected to the microscope to acquire magnified images of the microarray and of the tissue samples; a display connected to the imager for displaying tissue sample images; a processor coupled to the imager and operable in a first mode to acquire a low magnification image of the microarray; the processor being operable in a second mode to cooperate with the imager to acquire high magnification images of tissue samples displayed at low magnification; and the processor being operable in a third mode for indexing a tissue sample image with a tissue sample in the microarray. 48. An apparatus in accordance with claim 47 comprising: a remote display device to receive over a common communication channel the aforesaid data to display thereon a composite image of the microarray and a composite image of several fields of view of tissue sample at high magnification. 49. An apparatus in accordance with claim 47 wherein: the processor is operable in a fourth mode to provide a scanning pattern to locate tissue samples irregularly spaced in grid of the microarray. 50. An apparatus in accordance with claim 49 comprising: a marker positionable with respect to the irregularly spaced tissue dot to cause the imager to acquire high magnification images as determined by the marker's position. 51. A method of analyzing tissue dots arranged in columns and rows in a microarray on a microscope slide, the method comprising: scanning the microarray of tissue dots and providing magnified images of the microarray with the tissue dots in their respective columns and rows within the microarray; identifying each of the tissue dot images with respect to its row and column position of the tissue dot within the microarray; performing an analysis of a respective magnified image of a tissue dot; associate each analysis with each identified tissue dot to allow a later review of a tissue dot image and its analysis from the microarray. 52. A method in accordance with claim 51 comprising: performing a quantitative analysis on the tissue dot. 53. A method in accordance with claim 51 comprising: providing a composite magnified image of the tissue dots; and using the composite magnified image to locate tissue dots for analysis at higher magnification.