초록 ▼

A modular system is described for construction of fluid applicators for open or endoscopic surgery from modular components. Lengths of tubing of various lengths, and devices to be carried by said tubing, are pre-fitted with standard adapters to mate with each other, thereby forming cannula sections

A modular system is described for construction of fluid applicators for open or endoscopic surgery from modular components. Lengths of tubing of various lengths, and devices to be carried by said tubing, are pre-fitted with standard adapters to mate with each other, thereby forming cannula sections and applicator sections. Interconnectors may also be provided, particularly for provision of articulation. The tubing is preferably rigid, but may also be either flexible or permanently bendable. A device can then be constructed by selection of a suitable set of tubing lengths, adapters and applicators. Devices customizable for particular uses can be created with minimal expense. The system is especially suitable for delivery of fluids to tissue in endoscopic or other minimally invasive surgical procedures. Delivery of fluids forming structure at a tissue site, especially as a hydrogel, is a preferred use of the devices.

대표청구항 ▼

What is claimed is: 1. A method of conducting surgery, the method comprising: accessing a treatment site with a first device through a cannula, wherein the first device is a multicomponent device comprising a first unit and a second unit, the first and second units together defining a first articul

What is claimed is: 1. A method of conducting surgery, the method comprising: accessing a treatment site with a first device through a cannula, wherein the first device is a multicomponent device comprising a first unit and a second unit, the first and second units together defining a first articulating joint such that the two units which define the first articulating joint can move in three dimensions relative to each other; delivering a therapeutic agent to the treatment site via the first device; altering the first device to form a second device by replacing the first unit of the first device with a third unit to form the second device, such that the second and third units together define a second articulating joint wherein the two units which define the second articulating joint can move in three dimensions relative to each other; and delivering a therapeutic agent to the treatment site via the second device. 2. A The method of claim 1, wherein the first device comprises two or more modular units, at least one of which is capable of being interchanged during surgery, including at least a cannula section and an applicator section, wherein the first device is capable of being provided in a sterilized condition, and wherein the first device further comprises at least one adaptor section. 3. A method according to claim 1, wherein the first articulating joint is a snap-fit ball and socket joint. 4. A device method according to claim 1, wherein the first articulating joint comprises both a taper fit connection and a snap-fit ball and socket connection. 5. A method according to claim 1, wherein the first device further comprises at least one of a valve and a limiting orifice. 6. A method according to claim 1, in which the therapeutic agent is contained by a fluid which forms at least one structure at the application site. 7. A method according to claim 6, in which said structure includes sealings, adhesives, pavings, coatings, barriers, drug delivery depots, and tissue engineering matrices. 8. A method according to claim 6, in which said fluid forms the structure at the site by at least one of precipitation, coacervation, gelation, spontaneous reaction, or reaction stimulated by application of energy. 9. A method according to claim 1, wherein said first device is assembled from modules wherein at least one module comprises a molded part. 10. A method according to claim 9, wherein the at least one module has the attribute of at least one of radio-opacity; color-coding; controlled flexibility; lack of magnetic responsiveness; intraoperative removability; and passability therethrough of optical fibers or sensors. 11. The method of claim 2, wherein said applicator section is at least one of an open tube; a brush; a roller; a pad; a paddle; a nozzle; a molding member; and an expandable member. 12. A method according to claim 1, wherein the first device is sterilizable by at least one of gamma irradiation, electron-beam irradiation, ethylene oxide sterilization, plasma treatment, and autoclaving. 13. A method according to claim 1, wherein the therapeutic agent is selected for treatment of a predetermined medical condition. 14. The method according to claim 1, wherein at least one of the units comprises a molded part. 15. The method according to claim 1, wherein at least one of the units has the attribute of at least one of radio-opacity; color-coding; controlled flexibility; lack of magnetic responsiveness; intraoperative removability; and passability therethrough of optical fibers or sensors. 16. The method according to claim 2, wherein the applicator section is a brush. 17. The method according to claim 1, wherein at least two or more of the units slidably connect to one another in fluid communication with one another to form the articulated joint. 18. The method according to claim 1, wherein the first articulated joint further comprises a first slidably connectable piece and a second slidably connectable piece. 19. The method according to claim 18, wherein the first slidably connectable piece is affixed to the cannula section and the second slidably connectable piece is affixed to the applicator section. 20. A method as in claim 1, wherein the first articulating joint facilitates at least 90째 rotational movement of the first unit relative to the second unit. 21. A method as in claim 1, wherein the first articulating joint facilitates at least 180째 rotational movement of the first unit relative to the second unit. 22. A method as in claim 1, wherein the first articulating joint facilitates 360째 rotational movement of the first unit relative to the second unit.