초록 ▼

A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and/or malodor properties, hydrate a

A composition providing electrically conductive adhesive hydrogels suitable for use as skin contact adhesives and, particularly, suitable for use as an electrical interface for disposable medical devices. The present hydrogels provide for reduced skin irritation and/or malodor properties, hydrate a subject's skin, readily wet around a subject's skin surface hair, and protect against burning of a subject upon or due to electrical stimulation through the hydrogel. These hydrogels generally include a monomer, a first initiator, a solubilizer, and a cross-linking agent. The present hydrogels also desirably include a buffer system to help prevent discoloration of the hydrogels and/or hydrolysis of the hydrogels as well as to improve shelf-life. Other additives such as conductivity enhancers, pharmaceuticals, humectants, plasticizers, skin health agents, etc. may be added to the present hydrogels either before or after curing.

대표청구항 ▼

We claim: 1. An electrically conductive hydrogel formed from a composition comprising: a monomer; an initiator; a cross-linking agent; and a solubilizer selected from the group consisting of cyclodextrin, cyclodextrin derivatives, and hydrotropes. 2. The electrically conductive hydrogel of claim

We claim: 1. An electrically conductive hydrogel formed from a composition comprising: a monomer; an initiator; a cross-linking agent; and a solubilizer selected from the group consisting of cyclodextrin, cyclodextrin derivatives, and hydrotropes. 2. The electrically conductive hydrogel of claim 1 characterized in that the solubilizer allows for a higher initiator concentration to be solubilized in the composition; and such that the composition has a higher polymerizing potential than a similar composition without the solubilizer. 3. The electrically conductive hydrogel of claim 1 having a lower concentration of residual monomeric compounds present in the hydrogel than that of a similar hydrogel without the solubilizer. 4. The electrically conductive hydrogel of claim 1, wherein the solubilizer is selected from the group consisting of hydroxypropyl beta-cyclodextrin, gamma cyclodextrin, and methacryloyl cyolodextrin. 5. The electrically conductive hydrogel of claim 1, wherein the solubilizer comprises less than about 20% by weight of the composition. 6. The electrically conductive hydrogel of claim 1, wherein the composition further comprises a second initiator. 7. The electrically conductive hydrogel of claim 1, wherein the composistion further comprises a conductivity enhancer. 8. The electrically conductive hydrogel of claim 1, wherein the composition further comprises a buffer. 9. The electrically conductive hydrogel of claim 1, wherein the monomer comprises about 10% to about 80% by weight of the composition. 10. The electrically conductive hydrogel of claim 1, wherein the monomer comprises about 40% to about 75% by weight of the composition. 11. The electrically conductive hydrogel of claim 1, wherein the initiator comprises about 0.01% to about 2% by weight of the composition. 12. The electrically conductive hydrogel of claim 1, wherein the cross-linking agent comprises about 0.01% to about 2% by weight of the composition. 13. The electrically conductive hydrogel of claim 7, wherein the conductivity enhancer comprises less than about 5% by weight of the composition. 14. The electrically conductive hydrogel of claim 1, wherein the monomer is selected from the group consisting of N,N-Dimethylaminoethyl acrylate ammonium DMS, dimethyl amino ethyl methacrylate, acrylamido methyl propane sulfonic acid, and their salts. 15. The electrically conductive hydrogel of claim 1, wherein the initiator is a chemical or photo initiator. 16. The electrically conductive hydrogel of claim 1, wherein the initiator is a thermally activated chemical initiator. 17. The electrically conductive hydrogel of claim 16, wherein the thermally activated chemical initiator is selected from the group consisting of disulfide based, peroxide based, and persulfate based initiators. 18. The electrically conductive hydrogel of claim 16, wherein the thermally activated chemical initiator is sodium metabisulfite. 19. The electrically conductive hydrogel of claim 1, wherein the initiator is a hydrophobic initiator. 20. The electrically conductive hydrogel of claim 1, wherein the composition further comprises a skin health agent. 21. The electrically conductive hydrogel of claim 20, wherein the skin health agent is selected from aloe Vera, vitamin E, vitamin B, provitamin B, vitamin E acetate, and chitosan. 22. An electrically conductive hydrogel formed from a composition comprising: an ionic monomer; a first initiator; a solubilizer; and a cross-linking agent; wherein the solubilizer is selected from the group consisting of cyclodextrin and cyclodextrin derivatives. 23. The electrically conductive hydrogel of claim 22, wherein the composition further comprises a conductivity enhancer. 24. The electrically conductive hydrogel of claim 23, wherein the conductivity enhancer is an electrolyte. 25. The electrically conductive hydrogel of claim 22, wherein the composition further comprises a buffer. 26. The electrically conductive hydrogel of claim 22, wherein the monomer comprises about 10% to about 80% by weight of the composition. 27. The electrically conductive hydrogel of claim 22, wherein the monomer comprises about 40% to about 75% by weight of the composition. 28. The electrically conductive hydrogel of claim 22, wherein the first initiator is a hydrophobic initiator. 29. An electrode comprising an electrically conductive adhesive hydrogel formed from a composition comprising: a monomer; a first initiator; a solubilizer; and a cross-linking agent. 30. The electrode of claim 29 characterized in that the solubilizer allows for a higher initiator concentration to be solubilized in the composition; and such that the composition has a higher polymerizing potential than a similar composition without the solubilizer. 31. The electrode of claim 29 having a lower concentration of residual monomeric compounds present in the hydrogel than that of a similar hydrogel without the solubilizer. 32. The electrode of claim 29, wherein the solubilizer comprises less than about 20% by weight of the composition. 33. The electrode of claim 29, wherein the solubilizer of the composition is selected from the group consisting of cyclodextrin, cyclodextrin derivatives, and hydrotropes. 34. The electrode of claim 29, wherein the solubilizer of the composition is selected from the group consisting of hydroxypropyl beta-cyclodextrin, gamma cyclodextrin, and methacryloyl cyclodextrin. 35. The electrode of claim 29, wherein the monomer comprises about 10% to about 80% by weight of the composition. 36. The electrode of claim 29, wherein the monomer of the composition is selected from the group consisting of N,N-Dimethylaminoethyl acrylate ammonium DMS, dimethyl amino ethyl methacrylate, acrylamido methyl propane sulfonic acid and their salts. 37. The electrode of claim 29, wherein the first initiator is a hydrophobic initiator. 38. The electrode of claim 29, wherein the composition further comprises a second initiator. 39. The electrically conductive hydrogel of claim 22, wherein the composition further comprises a second initiator.